5ar

* Steroid 5a-reductases (5aRs) catalyze the irreversible, NADPH-dependent reduction of A*-3-ketosteroids. This process regulates major steroid signaling pathways, including neurosteroid biosynthesis, androgen activation, and glucocorticoid metabolism. By governing these processes, 5aRs influence...

5:25-6:43 (5α-Reductase, scar tissue/venous leak) *dihydrotestosterone is extremely important for the health of the smooth muscle cell of the penis , like really important Here is a nightmare condition in young men: erectile dysfunction due to venous leakage. While it is a neglected...

Purpose Androgenetic alopecia (AGA) is the most common type of hair loss in humans, affecting self-esteem and emotional well-being. This study aimed to assess the safety and efficacy of VISPOTM, a standardized saw palmetto oil (2–3% β-sitosterol), in subjects with mild-to-moderate AGA...

I started a previous thread to unravel the mystery of why hCG improves libido in some men, which generated some good discussion but didn't reach any firm conclusions: https://www.excelmale.com/forum/threads/libido-hcg-vs-higher-t-e2.25785/ Now comes a youtube video from Cortex Labs that claims...

I have access to a cream that is applied to the scrotum daily, which works really well, verified by testing. But I'm interested in more natural things, anything that might promote the 5AR conversion to DHT. I've investigated Sorghum and I do use Creatine but I don't think that those have had a...