androgen receptor

  1. madman

    Pathophysiology of Androgenetic Alopecia and Implications for Treatment

    Key points here! * Genetic variants, including polymorphisms in the androgen receptor (AR) gene, influence individual susceptibility and therapeutic response. Highlights * Androgenetic alopecia (AGA) is the most common form of hair loss, affecting both men and women through a progressive...
  2. madman

    Treatment of androgenetic alopecia / male and female pattern hair loss - new developments and recommendations

    Six patients with hair loss
  3. madman

    Management of androgenic alopecia:

    ABSTRACT We aimed to determine the efficacy of the various available oral, topical, and procedural treatment options for hair loss in individuals with androgenic alopecia. Using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, a systematic review of the...
  4. T

    Understanding free androgen Index

    Does anyone understand the implications of having a very high level of androgens despite being on a moderate dose of TRT. I’ve struggled for years to get “dialled” in. Mostly libido / ED I’m not one for chasing numbers per say but given all the variables, getting things into range is at least...
  5. madman

    Components of Cytoskeleton Strengthen Effect of Sex Hormones

    https://kommunikation.uni-freiburg.de/pm-en/press-releases-2023/components-of-cytoskeleton-strengthen-effect-of-sex-hormones#:~:text=Nadine%20Hornig%20is%20a%20research,the%20development%20of%20androgen%20resistance. Researchers from Freiburg and Kiel discover that actin acts in the cell...
  6. T

    Great articles and discussion on terminology ("anabolic steroids" don't really exist)

    https://forums.t-nation.com/t/what-is-trt-and-what-is-not-trt/269828/807 https://forums.t-nation.com/t/what-is-trt-and-what-is-not-trt/269828/811 https://forums.t-nation.com/t/what-is-trt-and-what-is-not-trt/269828/777 No such thing as anabolic steroids or AAS. Technically correct term is...
  7. madman

    Testosterone and the Androgen Receptor

    Testosterone and the Androgen Receptor (2023) Thomas Gerald, MD, Ganesh Raj, MD, PhD INTRODUCTION The steroid hormone testosterone is among the most widely studied in the endocrine system. Testosterone is the major sex hormone in men and critically influences male development and...
  8. madman

    Androgen synthesis and action

    Basics of androgen synthesis and action (2022) Rawda Naamneh Elzenaty, MSc, PhD Candidate Therina du Toit, PhD, Postdoc Christa E. Flück, PhD, MD, Professor Androgens are essential sex steroid hormones for both sexes. Testosterone (T) is the predominant androgen in males, while in adult...
  9. madman

    Variations in CAG Repeats of Men’s Androgen Receptor Gene

    As the mediator of androgen actions, the androgen receptor (AR) plays a central role in establishing both physical and behavioral sex differences. The AR gene contains a CAG repeat polymorphism that is related to the strength of androgen actions on target tissues and that is correlated with...
  10. B

    Can TRT reduce sensitivity of androgen receptors?

    Is this possible or does this happen? Naturally the body frequently fluctuates hormone levels, and in TRT we have a constant steady supply and also a lot of us are a slight bit higher than we would be naturally. I was wondering if anyone with some knowledge on androgen receptor sensitivity and...
  11. 3

    Androgen Receptor Health Assessment

    Is it possible to test/assess the health of one's androgen receptors? I am just curious if there are tests that will predict the efficacy of TRT and/or determine the timeline of expected benefits. I would imagine Thyroid (TSH, T3, T4) is obvious. What else can be tested to determine AR health?
  12. M

    Possible Role of Androgen Receptor in Various Cancers (not just prostate)

    Have you seen this study Androgen receptors beyond prostate cancer: an old marker as a new target Javier Munoz, Jennifer J. Wheler, and Razelle Kurzrock Abstract Androgen receptors (ARs) play a critical role in the development of prostate cancer. Targeting ARs results in important salutary...

androgen receptor

androgen receptor

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