Bat

* Currently, no clear guidelines exist, leaving clinicians to rely on incomplete but available clinical evidence. Although TST may be necessary in cases, such as successful PCa treatment or active surveillance for low-risk disease, extreme caution is advised for patients with moderate- or...

* This approach involves administering high doses of testosterone, which has shown significant improvement in 30% of patients, enhancing strength, energy, and sexual function * their research uses blood-based DNA markers to predict which patients will respond best, aiming to personalize...

https://ascopost.com/videos/2024-asco-annual-meeting/alicia-morgans-and-samuel-denmeade-on-prostate-cancer-results-from-the-transformer-trial/

The video presented a treatment called Bipolar Androgen Therapy (BAT) for prostate cancer, in which patients are given high doses of testosterone to resensitize the cancer to hormone therapy. Dr. Sam Denme discussed the concept, results from trials, and future research, highlighting the...

Loved this one! True Warrior! “If we continue to do the same things, we will get the same results.” “If BAT can be used to sensitive Xtandi/darolutamide ad infinitum, prostate cancer becomes a treatable condition like diabetes.” – Russ Hollyer Meeting Summary Advanced prostate...

https://www.urotoday.com/video-lectures/pcf-2022/video/2959-bipolar-androgen-therapy-in-the-management-of-prostate-cancer-samuel-denmeade.html Samuel Denmeade, Co-Director of the Johns Hopkins Prostate Cancer Program joins Alicia Morgans in a discussion on Bipolar Androgen Therapy (BAT) for...

Transdermal square-wave testosterone therapy: A pilot trial in metastatic castration-resistant prostate cancer (2023) Nellowe Candelario, Andrew Nicklawsky, Laura Graham, Elaine T. Lam, Eryn Callihan, Michael Wacker, Thomas W. Flaig, Elizabeth R Kessler; the University of Colorado Cancer Center...

Bipolar Androgen Therapy Followed by Androgen Receptor Inhibition as Sequential Therapy for Prostate Cancer (2023) Samuel R. Denmeade*,Laura A. Sena, Hao Wang, Emmanuel S. Antonarakis, Mark C. Markowski Abstract Inhibition of androgen receptor (AR) signaling has been the mainstay of treatment...

The testosterone paradox of advanced prostate cancer: mechanistic insights and clinical implications (2022) Rajendra Kumar, Laura A. Sena, Samuel R. Denmeade & Sushant Kachhap Abstract The discovery of the benefits of castration for prostate cancer treatment in 1941 led to androgen...