gnrh

I have read in this and other forums that taking clomid, gonadorelin, or kisspeptin while on TRT is a waste - that those things are used more for PCT, to regain testicular function. But why is it wasteful, or even contraindicated, to use those medications while on TRT? How does one harm the...

https://academic.oup.com/endo/article-abstract/165/2/bqad194/7505543?redirectedFrom=fulltext&login=false Abstract There is considerable evidence that synchronized activity within a reciprocally connected population of cells in the arcuate nucleus (ARC) coexpressing kisspeptin, neurokinin B...

Gonadotropin-Releasing Hormone (GnRH) is a peptide controlling reproductive functions. It binds to GNRHR receptors and has diverse effects. GnRH plays a role in infertility, reproductive disorders, assisted reproduction technology, endometrium, ovary, prostate physiology, tumor transformation...

https://www.sciencedirect.com/book/9780128216767/human-gonadotropins#book-description Function of gonadotropin releasing hormone and inhibin (2022) Marja Brolinson, Ariel Dunn, Joshua Morris, and Micah Hill Gonadotropin-releasing hormone Neuroanatomy The hypothalamus is located at the...

I am getting off testosterone after two years (if you want back story, you can read my previous posts, and I'm unable to perform any conventional PCT as I cannot tolerate SERMs. I have, however, been entertaining the idea of using GnRH or hCG as a way to "prime" the body before coming off TRT...

TL;DR: Over a period of seven weeks, treatment with GnRH and enclomiphene raised LH and FSH from around 0.1 mIU/mL to about 1.0 mIU/mL, even though TRT and hCG dosing were continued. Subjective results have been encouraging. I had written previously on the subject of GnRH suppression on TRT...

Admittedly the last thing we need is some other nebulous danger to worry about that may not even exist. Read on at your peril. TL;DR: Testosterone replacement therapy suppresses the production of GnRH. Receptors for GnRH are found in places besides the pituitary. One animal model suggests GnRH...

Factors affecting spermatogenesis upon gonadotropin-replacement therapy: a meta-analytic study. Rastrelli G, Corona G, Mannucci E, Maggi M. Andrology. 1 OCT 2014 A meta-analysis was performed to systematically analyse the results of gonadotropin and GnRH therapy in inducing spermatogenesis...