mitochondria

* Currier explains MitoPure’s mechanism—stimulating mitophagy to recycle dysfunctional mitochondria—and reviews evidence from multiple clinical trials. He reveals a Sports Medicine study in elite male distance runners showing reduced creatine kinase and lower perceived exertion, suggesting...

* In this episode, the conversation begins with Urolithin A and Mitopure, exploring what it is, what it does in the body, and why it has become an area of interest for mitochondrial health and muscle function. Brad explains the proposed mechanisms, the current human evidence, and what outcomes...

Dr. Mark Tarnopolsky's VO2 max was once 87.6 ml/kg/min — an elite-level mark few humans have reached. He's competed at three world championships in three different sports. He's also had three cardiac ablation surgeries, bled from his bowels after races, and watched his vision tunnel to a speck...

From my neck of the woods. Dr. Mark Tarnopolsky is a world-renowned expert in mitochondrial health, muscle function, and ageing science. As a clinician-scientist at McMaster University, he has dedicated his career to understanding how we can optimise our mitochondria - the tiny...

Prof. Stuart Phillips, Ph.D. (McMaster University) ‘Mitochondrial Health: A key to Aging & Recovering Well' presentation at the American College of Sports Medicine (ACSM) annual meeting 2022. 2:40 - Sarcopenia: the age-related decline in muscle mass, strength, and function 4:41 - Declines in...

The doses used were high to common standards: 100mg/kg Glycine per day 100mg/kg NAC per day a 70kg (154lb) human would have to take 7g Glycine and 7g NAC per day GlyNAC (Glycine and N-Acetylcysteine) Supplementation Improves Impaired Mitochondrial Fuel Oxidation and Lowers Insulin Resistance...

The doses were a bit high: 1.33 mmol/kg/d of glycine = 100mg/kg per day 0.81 mmol/kg/d of cysteine (as N-acetylcysteine) = 100mg/kg per day a 70kg person (154lb) would have to take 7g Glycine and 7g NAC per day. Effect of Increasing Glutathione With Cysteine and Glycine Supplementation on...

GlyNAC (Glycine and N-Acetylcysteine) Supplementation in Mice Increases Length of Life by Correcting Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Abnormalities in Mitophagy and Nutrient Sensing, and Genomic Damage Supplementing Glycine and N-Acetylcysteine (GlyNAC) in...