sarcopenia

  1. madman

    Enhancing Muscle Quality: A Deep Dive into Mitochondrial Science, Part 1/2

    * Currier explains MitoPure’s mechanism—stimulating mitophagy to recycle dysfunctional mitochondria—and reviews evidence from multiple clinical trials. He reveals a Sports Medicine study in elite male distance runners showing reduced creatine kinase and lower perceived exertion, suggesting...
  2. madman

    Brad Currier discusses Urolithin A and Resistance Training Guidelines

    * In this episode, the conversation begins with Urolithin A and Mitopure, exploring what it is, what it does in the body, and why it has become an area of interest for mitochondrial health and muscle function. Brad explains the proposed mechanisms, the current human evidence, and what outcomes...
  3. madman

    Protein after 40: what does the science actually say about muscle health and aging?

    ABOUT PROFESSOR LUC VAN LOON: Professor Luc van Loon is Professor of Physiology of Exercise at Maastricht University in the Netherlands. He is one of the world's leading researchers on muscle protein metabolism, with particular expertise in how nutrition and exercise affect muscle health across...
  4. madman

    Building Muscle Masterclass: Protein and Lifting with Dr. Stu Phillips

    In this Building Muscle Masterclass, I sit down with Dr. Stu Phillips — the world’s most cited researcher in exercise science and protein metabolism. If you care about building muscle, eating enough protein, lifting smarter, or cutting through the noise in the fitness world, this is a...
  5. madman

    Experts Settle the PROTEIN Debate

    Bringing together two of the top minds, with differing (though less so now than ever before) perspectives on protein as it relates to health from multiple different angles, watching their circles of agreement overlapping more and more in real time, is amazing. But we push the envelope, ask the...
  6. madman

    Beyond Blood Sugar: GLP-1 Receptor Agonists as a Multifaceted Therapy for Testosterone, Erectile Function, and Metabolic Outcomes in Men with Obesity

    * Given emerging data on sarcopenia and GLP-1 RAs, future studies should investigate the potential role of combined GLP-1 and testosterone therapies to optimize outcomes in body composition, metabolic control, and sexual health. Table 1. Impact of GLP-1 Receptor Agonist Therapy on...
  7. madman

    Mitochondrial Mastery: Supplements, Exercise & Longevity Insights

    From my neck of the woods. Dr. Mark Tarnopolsky is a world-renowned expert in mitochondrial health, muscle function, and ageing science. As a clinician-scientist at McMaster University, he has dedicated his career to understanding how we can optimise our mitochondria - the tiny...
  8. madman

    LPCN 1148 ( oral T dodecanoate) as a treatment for sarcopenia in patients with decompensated cirrhosis

    * LPCN 1148 comprises testosterone dodecanoate, a unique androgen receptor agonist https://www.lipocine.com/news-article/fda-grants-fast-track-designation-to-lipocine-for-lpcn-1148-as-a-treatment-for-sarcopenia-in-patients-with-decompensated-cirrhosis/ SALT LAKE CITY, Dec. 17, 2024...
  9. madman

    Creatine Supplementation + Resistance Training To Treat Sarcopenia

    Don't miss out this talk on "Creatine (+RT) and Sarcopenia" by Prof. Scott Forbes, PhD from Brandon University, Canada. This presentation was part of the 1st Chilean Symposium "Creatine for Health," led by DBSS in Santiago de Chile. The symposium took place during the 1st SOCHIKIMET Conference...
  10. madman

    Muscles in Menopause

    Move Daily Talks: Muscles in Menopause with Stuart Phillips Ph.D. | EPS. 3 Stuart Phillips Ph.D. discusses the challenges and strategies for building lean muscle during menopause, emphasizing the importance of resistance training, adequate protein intake, and consistent exercise habits, while...
  11. madman

    Enobosarm and GLP-1 receptor agonist Combination to Treat Muscle Loss Associated with Weight Loss Drugs

    Sign in for free to view! https://ir.verupharma.com/news-events/ir-calendar/detail/20240214-oppenheimer-34th-annual-healthcare-life-sciences-conference https://wsw.com/webcast/oppenheimer33/register.aspx?conf=oppenheimer33&page=veru&url=https://wsw.com/webcast/oppenheimer33/veru/2819844
  12. madman

    Clinical Trial with Enobosarm to Treat Muscle Loss Associated with Weight Loss Drugs

    https://ir.verupharma.com/news-events/press-releases/detail/196/veru-announces-fda-clearance-of-ind-application-to-initiate Veru Announces FDA Clearance of IND Application to Initiate Phase 2b Clinical Trial with Enobosarm to Treat Muscle Loss Associated with Weight Loss Drugs FDA IND...
  13. madman

    Optimizing Protein Intake for Muscle Growth

    13:04-20:35 *The primary driver of accumulating new muscle is definitely the weightlifting lets be clear on that and the protein is the icing on the cake! Pay close attention (16:30-17:32, 41:50-43:23) How much protein can your body actually use in one sitting? Is there an upper limit...
  14. madman

    Building and maintaining muscle for longevity

    Steeltown! Stuart Phillips, PhD, is a professor of kinesiology at McMaster University in Hamilton, Ontario, Canada, where he also serves as the director of the Physical Activity Centre of Excellence. His research centers on the roles exercise and nutrition play in influencing human...
  15. madman

    Novel dietary strategies to manage sarcopenia

    Purpose of review Sarcopenia is a wasting disease, mostly age-related in which muscle strength and mass decline, such as physical performance. With aging, both lower dietary protein intake and anabolic resistance lead to sarcopenia. Moreover, aging and sarcopenia display low-grade inflammation...
  16. madman

    Current Landscape of Pharmacotherapies for Sarcopenia

    Getting deep here, enjoyed this one! Abstract Sarcopenia is a skeletal muscle disorder characterized by a progressive and generalized decline in muscle mass and function. Although it is mostly known as an age-related disorder, it can also occur secondary to systemic diseases such as...
  17. madman

    The role of dietary protein in muscle, health, and disease

    In this episode of STEM Talk, Dr. Donald Layman discusses the importance of dietary protein in muscle development, health, and disease. He shares his research on protein synthesis, metabolic regulation, and the impact of diet and exercise on adult health problems such as obesity, diabetes, and...
  18. madman

    Novel Approach for the Management of Liver Cirrhosis

    https://ir.lipocine.com/events?item=45
  19. madman

    Mitochondrial Health: A key to Aging & Recovering Well- Urolithin A Supplement

    Prof. Stuart Phillips, Ph.D. (McMaster University) ‘Mitochondrial Health: A key to Aging & Recovering Well' presentation at the American College of Sports Medicine (ACSM) annual meeting 2022. 2:40 - Sarcopenia: the age-related decline in muscle mass, strength, and function 4:41 - Declines in...
  20. madman

    The anabolic applications of androgens in older adults with functional limitations

    The anabolic applications of androgens in older adults with functional limitations (2022) Arijeet K. Gattu · Anna L. Goldman · Ezgi Caliskan Guzelce · Francesca Galbiati · Shalender Bhasin Abstract Aging is associated with a progressive decrease in skeletal muscle mass, strength, and power...
  21. madman

    Effects of creatine supplementation on sarcopenia, osteoporosis, frailty, and Cachexia?

    Creatine supplementation for older adults: Focus on sarcopenia, osteoporosis, frailty, and Cachexia (2022) Darren G. Candow, Philip D. Chilibeck, Scott C. Forbes, Ciaran M. Fairman, Bruno Gualano, Hamilton Roschel ABSTRACT Sarcopenia refers to the age-related reduction in strength, muscle...
  22. madman

    Three Questions with Sarcopenia

    Three Questions with Sarcopenia 2 Principal Investigators Dr. Shalender Bhasin and Dr. Peggy Cawthon https://fnih.org/news/announcements/three-questions-with-sarcopenia2-principal-investigators September 21, 2020 — The FNIH Biomarkers Consortium Sarcopenia 2 project, Sarcopenia as a Valid...
  23. J

    Testosterone and Exercise for Non-hypogonadal Older Men

    Putting non-hypogonadal men on testosterone in order to reverse muscle wasting. The article says: Eighteen non‐hypogonadal healthy older men, 65–75 years, were assigned in a random double‐blinded fashion to receive, biweekly, either placebo (P, saline, n = 9) or T (Sustanon 250 mg, n = 9)...
  24. J

    Dysregulated Hormonal Pathways in Sarcopenia

    Analysis of hormone levels in older men in Sigapore suffering from sarcopenia showed that both dysregulated insulin/ghrelin and testosterone are responsible for muscle wasting. The full text of the article is online. "Insulin signaling and energy metabolism (ISEM: denoted by insulin, C‐peptide...
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