acne

* Androgens contribute to acne through increased sebum production, abnormal desquamation/comedone formation, and inflammation. https://www.hmpgloballearningnetwork.com/site/thederm/videos/hormonal-therapy-acne-dht-spironolactone-and-clascoterone Dr Lawrence Green discusses how androgens...

I'm John Barbieri, MD, a board-certified dermatologist and acne expert at the Brigham and Women’s Hospital and Harvard Medical School. In this video we provide a comprehensive overview of how to treat acne in 2026. We will review skincare, over-the-counter products, prescription medications...

* Importantly, she cautions that normal serum androgen levels do not rule out hormonally driven acne, as androgen activity within the skin is not directly reflected by circulating levels...

I am not on TRT or any hormones. However, over the last few months for some reason I’ve been having breakouts on my chest and to some degree my back. But mainly, I have these tiny white bumps all over my chest and back. If anyone knows what this is and has any idea what I can do to get rid of...

* Trifarotene not only treats acne but also improves scarring and pigmentation. * Clinical trials show significant efficacy in both facial and truncal acne. In this episode of the Science of Skin podcast, Dr. Ted Lain and Dr. Andrew Alexis discuss trifarotene Cream, a novel...

Neil Skolnik, MD, discusses the latest evidence-based guidelines from the Primary Care Dermatology Society regarding the treatment of acne. The video outlines a streamlined clinical pathway, beginning with topical retinoids and fixed-dose combination therapies for mild-to-moderate cases, and...

I’ve had acne on my back, face, and chest for 6 years or so now and it’s gotten really bad. I’ve tried a ton stuff of course but I think that what I need is a really severe full body detox. I don’t really know how to do that and I did one short protocol that I got prescribed and as well as some...

* Kristina Derrick, MD, ScM—named Rookie of the Year at the 2026 Masters of Pediatric Dermatology (MOPD) meeting—brings a dual-disciplinary perspective that reframes acne not simply as a cutaneous disorder, but as a reflection of pubertal physiology, metabolic health, and androgen signaling...

I started sermorelin a month ago. After a couple of weeks, I started noticing my acne getting really bad. Has anyone else experienced this? I contacted my provider and he said I should talk to a dermatologist. He was unhelpful. I’m not going to keep using it if it gives not acne. I stopped...

Very thorough worthy of a sticky! Really enjoyed this one!

* Acne and other cutaneous reactions vary by delivery method and patient susceptibility, emphasizing the need for clinician awareness, patient counseling, and better adverse event reporting. https://academic.oup.com/jsm/article/22/Supplement_4/qdaf320.197/8375218 Testosterone Replacement...

Amanda Nelson, PhD, Associate Professor of Dermatology, Department of Dermatology, Penn State College of Medicine names a potential new therapeutic for severe acne and describes how her lab identified the candidate. Presentation from the 12th AARS Annual Scientific Symposium at SID, 2025...

This ones going out to all those bros stinkin' up those so called HRT/men's health forums! Stop f**king blaming high estradiol! Critical points here! * The four established pillars of acne pathogenesis are sebum production, follicular hyperkeratinization, Cutibacterium acne (C. acnes)...

Dr. Lawrence J Green from Skinalliance LDB discusses if androgen hormones cause hair loss and acne. Learn more about the effects of testosterone and creatine on your skin health. In this informative video, Dr. Lawrence J. Green delves into the relationship between androgen hormones and common...

Could mTOR inhibitors offer a new treatment option for acne vulgaris? Mackenzie Sennett, BS, of Penn State College of Medicine in Hershey, PA, talks about the rationale for his team's research and the implications of their findings. Mr. Sennett presented research at the AARS Annual Scientific...

With a recent publication assessing the frequency of lab monitoring for patients with acne being treated with isotretinoin, AARS President Elect Jonathan Weiss, MD, FAAD, weighs in on the latest expert thinking. He also compares the current publication to the Guidelines of Care for Acne from the...

Hey everyone, I have been on 100mg of Testosterone Cypionate & 750 iu hCG for 8 weeks. My subcutaneous injection schedule is as follows: 20mg Test C - Monday, Wednesday, Friday, Saturday & Sunday 250 iu hCG - Tuesday, Thursday and Sunday I have never had acne this bad before. My back and...

* Four main interrelated pathogenic factors, that act synergistically in a complex manner are involved in the development of acne lesions: 1. Increased sebum production due to androgen-driven sebaceous gland hyperplasia; 2. Hyperkeratinization of the follicular epithelium due to abnormal...

Hey guys, I’ve been on 100mg of Testosterone Cypionate weekly, broken up into 5 subcutaneous injections in the stomach/love handle area. It has been 4.5 weeks since I started. I am also taking 750ius of HCG. I have begun getting small pimples on my arms and shoulders. I’ve never had body...

Androgens are a key factor in acne pathogenesis. Lawrence Green, MD, FAAD discusses how hormones help drive the skin disease. How DHT and Androgens Drive Acne Formation Androgens are integrally associated with acne development. Acne originates in the sebaceous gland, which is under androgen...

Abstract Acne scarring is a frequent complication of acne. Scars negatively impact psychosocial and physical well‐being. Optimal treatments significantly improve the appearance, quality of life, and self-esteem of people with scarring. A wide range of interventions have been proposed for acne...

Background Acne vulgaris commonly affects adults, adolescents, and preadolescents aged 9 years or older. Objective The objective of this study was to provide evidence-based recommendations for themanagement of acne. Methods A working group conducted a systematic review and applied the...

ABSTRACT Background Sebum physiology and its contributions to acne vulgaris (AV) pathophysiology have been long debated. Within the pilosebaceous unit, androgens drive sebocyte production of sebum, comprising mono-, di-, and triglycerides (the latter converted to fatty acids); squalene...

Deca Base Trial Hello. I am 35 been on TRT for 5 years and for the most it’s all been positive. I recently switched over to Defy and mentioned the sides I have been having and learned to live with as they aren’t detrimental but annoying. The sides are oily face, acne, slight loss of penile...

https://www.bmj.com/content/383/bmj.p2545 Elisabeth Mahase Two prescribers, including a dermatology specialist, must now sign off new prescriptions of the acne medicine isotretinoin (brand names include Roaccutane and Reticutan) for patients aged under 18,1 after concerns were raised over...

Finasteride and dutasteride, known as 5-alpha reductase inhibitors (5ARIs), are used to treat benign prostatic hyperplasia and androgenetic alopecia. These drugs block the conversion of testosterone to dihydrotestosterone, which affects the neuroendocrine system. They have potential applications...

So after about 6 years on TRT (Im 47), Im thinking about coming off. I'm someone who was never crazy low in the first place, I just wanted to see if I would get a bit of a boost. The only boost I've seen is in muscle mass. When I weight the pros and cons, I'm thinking it might be time to come...

So after about 6 years on TRT (Im 47), Im thinking about coming off. I'm someone who was never crazy low in the first place, I just wanted to see if I would get a bit of a boost. The only boost I've seen is in muscle mass. When I weight the pros and cons, I'm thinking it might be time to come...

Hello, I am 35 175lbs 5’11 and have been on TRT for 2 years. I have been trying to find my sweet spot and get dialed in the majority of the 2 years. I work out 6 days a week and eat very healthy etc…My current issues are: Back acne Oily face Low libido Testes and penis always feel cold and have...