anxiety

Curated By Nelson Vergel | ExcelMale.com | Updated June 2026 If you've been on TRT for a while and still deal with flat libido or low motivation - even with testosterone in a solid range - there may be more happening than your T levels alone can explain. One underappreciated piece of that...

Discover how a single high dose of psychedelic medicine impacts the neurological framework of individuals without pre-existing clinical conditions. This video breaks down a recent clinical trial evaluating psilocybin effects on healthy adults to understand its acute and long-term impact on the...

Started TRT at 34 with total testosterone of 13.6 nmol/L and free testosterone of 0.25, symptomatic with low mood, overthinking, fatigue and poor motivation/work/gym performance. Currently on 30mg twice weekly (60mg total) which I know is a low dose, but even at this level I'm experiencing...

Mental and sexual health are deeply connected, but how much do those connections affect sexual function and performance? Sexual medicine and mental health expert Dr. Christian J. Nelson joins us to explore the relationship between psychological well-being and sexual health, and how these factors...

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Sorry for the long trainwreck of a post but I have never been so scared in my life as I’ve been the last 2mos. Before that I’d say I barely ever had anxiety at all, about anything. I’m usually the one who likes taking risks and is always level-headed and calm/confident. I think I’ve been messing...

The psychedelic drug development landscape has reached an inflection point in early 2026, with Compass Pathways achieving the first positive Phase 3 psilocybin trial results in June 2025, while Lykos Therapeutics' MDMA rejection has reshaped industry expectations for regulatory rigor. Six...

Is your performance anxiety causing erectile dysfunction? In this video, Sexologist and Urology Nurse Practitioner Melissa Hadley Barrett from Restorative Health Clinic explains how performance anxiety can affect erections, and how fast-acting options like Spontan nasal spray may help some men...

Ibogaine is rapidly garnering attention as a potentially revolutionary treatment for addiction and related mental health disorders—a beacon of hope in landscapes often characterized by despair and systemic inadequacy. In a recent Fluence webinar, leading experts Dr. Bruno Rasmussen (Brazilian...

Hi guys. You are probably sick of me by now but here it goes. So im 3 weeks into my new dose of 94mg a week split into every 3.5 days. Yesterday after my injection all day my anxiety ramped up and felt so off. No energy, felt off balance at times, and just wanted to rest. I take insulin...

* Psychedelics are not panaceas, but they offer mechanisms of action distinct from conventional treatments. Substances such as MDMA, psilocybin, ibogaine, ketamine, and 5-MeO-DMT are demonstrating the capacity to disrupt entrenched neurobiological patterns associated with trauma, addiction, and...

I have been on transscrotal testosterone crème for about a month now. All of a sudden my anxiety is as bad as it has ever been. I am not blaming the testosterone, but is it a possibility? If so do all methods of testosterone cause possible anxiety?

Good morning everyone, I am reaching out for some help after a year and a half period on TRT. I was on TRT initially with TRT nation but didn't feel that they were worth the money so I went on getting T through underground sources for the rest of the time. I ran various doses and experimented...

I know this has been discussed on the forum, but I wanted to relate to how much TRT has improved my anxiety for those who search and ask about this issue. For most of my life, I have had GAD (Generalized Anxiety Disorder). I take an anti-anxiety medication called Clonazepam and have been doing...

https://www.endocrine-abstracts.org/ea/0109/ea0109oc3.6 Background The most well-described pathway for kisspeptin’s activation of the reproductive axis relies on activation of kisspeptin receptors on GnRH-neurons in the hypothalamus. However, recent evidence has identified an...

Its been nearly a week since I got the okay from my provider to double my Kyzatrex dose from 200mg twice a day to 400mg twice a day. Ever since, I've noticed anxiety creeping in, usually in the evenings. I take my second dose at around 2pm. Has anyone else experienced this when changing...

Hello everyone, Desperate for some help. I’m 23 years old. I’ve been bodybuilding for 8 years, and started competing at 21. I was prepping to compete at nationals this summer before everything went wrong. I was on a test only cycle around June and started to get some gyno symptoms. All I...

Hello everyone, I hope everyone is doing well and is excited for the holidays coming up. After years of experimenting, pain, insomnia and more I believe I have finally found a protocol that works for me! Solvent free propionate 12mg before bed with 5mg topical dhea in the morning Funkodyssey...

Hi all - just signed up today and happy to be here. I’m 46 years old, in decent physical shape but for over 8 months had the classic low T symptoms (lethargy, anxiety, brain fog, poor sleep, low libido, poor workout recovery). An initial blood test confirmed this, so having signed up with Leger...

This might seem stupid, but here me out…. Long story short: I have treatment/lifestyle/therapy resistant depression, mental fatigue, anxiety. You name it, I’ve tried it. Believe me. Both medical and underground. Doctors are at a loss. But one day I decided to try testosterone and….. bam. Total...

https://www.endocrine-abstracts.org/ea/0099/ea0099oc9.4 Background The neuropeptide kisspeptin is a key endogenous activator of the reproductive system. Due to its crucial role in modulating reproductive and behavioural processes, there has been accelerating interest in targeting...

Hey guys, Been on TRT for nearly 8 years now thru a local clinic, at a dose of .4ml cypionate 1x weekly, never really any issues minus the first couple weeks. Which I understand spitting doses provides a more stable level. Recently I switched from a local clinic to trtnation so I could...

Psychedelics have helped me and many others that I know through real dark times of addiction and depression. My own breakthrough with psychedelics provided the breaking down of my belief systems and reawakened an overwhelmingly empowering sense of my own ability to change. I’m super excited...

Hi Everyone: Hoping for some feedback here. I am on 150mg per week of testosterone cypionate, broken up into 2x per week injections. Has anyone has an issue with feeling like shit, with anxiety and just a general 'off' feeling, for 24 hours or so after each injection? I can't put my finger on...

Hi guys the Mrs and I are wanting to start a family but it's a problem my side last seman analysis was azoospermia I take hcg 2000iu x3 a week and menopor 225iu x2 a week I'm worried about my recent blood tests my androgen level is 20.6!

Hi all! It’s refreshing to find a place to talk about these things with guys who have been there or are there currently. To start off I have average T and nothing really to complain about. However I have felt that I could use a boost if some kind. I have had intermittent bouts with ED and lack...

Hello crew. Anyone of you guys had this experience? I've been on TRT 100mg/week of Testosterone Enanthate for around 10 months without any problems and was feeling great. Just now remembered that I've changed to Sustanon250 recently and in some time I started getting all these issues...

Looking for some advice on switching to Cream or to Enanthate? Been on HRT with Defy for about 8-9 years now. I just can't beat the anxiety that I get after my injection. It's not from the fear of the injection itself, it's the 12-24 hours after the injection. I get major anxiety and panic...

So my doc has me on 60mg test cyp M W F and 0.125g anastrozol M-F with nothing at all on weekends. It's been this way for a number of months and things are generally good. Labs show good T levels and "acceptable" e2. Strength, recovery, and libido are great, but mood is not consistently good. I...

Hello Everyone - 39 year old male, 220lbs 12% bodyfat looking to regain his health. Ive been sick for a long time. Here is my story. I was a competitive bodybuilder and did 5 regional shows and 5 national shows from 2009-2016...but during that time I knew things weren't right. I have a...

Hey All. I have been experiencing palpitations and frequent anxiety for the last few weeks. Sometimes its debilitating. It causes insomnia. Sometimes thoughts of something life threatening happening in my sleep. I am 33 yr old. Workout 6 days a week vigorously. Eat a good diet. I'm 5' 10" and...