free testosterone

Only at Excel, are we gonna take you deep! Clinical Utility and Analytical Aspects of Direct Measurements of Free Hormones Using Mass Spectrometry-Based Methods (2022) Mark M. Kushnir, Heather A. Nelson, and Kelly Doyle Background The free hormone (FH) hypothesis states that hormone...

This is a bit wordy but I want to share what is working for me take get estrogen under control. I've been on TRT for over 6 years and estrogen has been my challenge. If you have battled this issue while on TRT, maybe this will work for you. And maybe I'm a slow learner and most of solving the...

Just got my labs back, and I'm surprised. I was expecting my numbers to be off. I have been feeling just off, not seeing any progress in my body, and I lift 3–5 times a week. Struggling with weight loss, and I inject only once a week because injecting more than once has always made me fatigue...

Estradiol: 64.2. (since this result, I started taking arimidex .5 mg (1/2. tablet) twice per week Testosterone total: 1,190 Testosterone free: 25.6 What is the best range for best results? I know the estrogen was too high...

Do you inject less than 50 mg of T per week? If so, how do you feel? What were/is your lab results before/after you started TRT? I am on 60 mg with high FT, T and E2. I am considering 50 mg, or even less. I'm on Enathate.

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Measurement and reporting of clinical testosterone diagnostics: a European survey (2023) *Three fractions circulate in plasma: the unbound (free) fraction, the fraction bound to specific binding proteins, such as sex hormone-binding globulin (SHBG) and vitamin D binding protein (DBP); and the...

Newly Observed Interference of Oral Biotin with the Free Testosterone Assay? In a Woman with Postmenopausal Virilization (2022) Rafael Caputi, MD and Alejandro Ayala, MD Introduction Approximately 15-20% of US adults take supraphysiologic doses of biotin-containing supplements for common hair...

Do you know the difference between free and total testosterone? Most people don't, but it's an important distinction. Watch this video to learn more about these two measures of testosterone and what they mean.

Reproductive Endocrinology ODP419 Measurement of Free Testosterone in Serum using Equilibrium Dialysis Coupled with ID-UHPLC-MS/ MS: in Comparison to Calculated FT Hui Zhou, Ph.D., Ashley Ribera, BS, Uliana Danilenko, Ph.D., Otoe Sugahara, BS, and Hubert Vesper, PhD Assessment of free...

Again you heard it here first only at Nelson's ExcelMale! @Nelson Vergel Was going to drop this bomb a few days ago but you let down the curtains early LOL! https://onlinelibrary.wiley.com/doi/abs/10.1111/andr.13310 Reference Intervals for Free Testosterone in Adult Men Measured Using a...

Hello, I have been on TRT for 9 years, I have done it all once weekly, twice weekly , EOD , and daily injections. Im currently been settled in on the dose of 14MG Daily of Test E. No other meds involved in terms of TRT. My recent labs from Quest Total T 881ng/dl LCMS Free T 249.9pg/ml...

Role of sex hormone‑binding globulin in the free hormone hypothesis and the relevance of free testosterone in androgen physiology (2022) N. Narinx · K. David1, · J. Walravens · P. Vermeersch · F. Claessens · T. Fiers · B. Lapauw · L. Antonio, · D. Vanderschueren Keep in mind this is...

Gentlemen, My free T (details below) is in the middle of normal range per Quest. But, I feel really sluggish and I am working on figuring out (a) why? and, (b) how to treat it? I am trying to get a sense of where most guys feel "optimal" relative to their free T. I know there are a myriad of...

Accurate measurement of total and free testosterone levels for the diagnosis of androgen disorders (7/2022) Ezgi Caliskan Guzelce, MD, Clinical/ Research Fellow, Francesca Galbiati, MD, Fellow, Anna L. Goldman, MD, Assistant Professor of Medicine, Arijeet K. Gattu, MD, Fellow, Shehzad Basaria...

I am hoping someone can shed some light on my current situation: 40 year old male, 5'10, 180 lbs Symptoms: Low energy, zero libido, poor recovery from exercise, fatigue Lifestyle: Don't drink, don't smoke, eat 40% carbs, 30% fat and 30% protein and 3000-4000 calories a day depending on energy...

What to Measure: Testosterone or Free Testosterone? (2021) Christina Wang and Ronald Swerdloff 1.1 Why Serum Testosterone Is Necessary for the Diagnosis of Testosterone Deficiency? Low serum testosterone (T) levels in adult men can lead to significant clinical symptoms and signs of...

Like the title says. I know this is kind of a person specific and subjective question: For a sense of wellbeing, does Total Testosterone need to be high alongside a high Free T? Or would a normal Total T and high Free T yield similar results? Basically, I'm wondering if Total testosterone...

SHBG (sex hormone binding globulin) controls how much testosterone is biologically active. What it is, why it matters, and how to raise or lower it naturally. My question might be a basic one, but what is the purpose of Sex Hormone Binding Globulin (SHBG)? In general terms I appreciate that...

The US generally use nanograms/decilitre and picograms/millilitre, other countries, including New Zealand, use nanomoles/litre and picomoles/litre for their Free Testosterone results. I set out to find the conversion values. I found two useful links that can with some thought provide the...

I was using an online calculator to see what my free T is from Quest to Labcorp, where on quest my free T is top of range in pg/mL, and Labcorp was ng/dL (I think?). Anyway, converting my top of range free T to Labcorp free T in their Unit resulted in having a free T in the middle of Labcorp's...

Hi guys . My mate is on 50mg gel a day. After about three months he is experiencing really bad headaches . I said 50mg is alot a day ... . I'm thinking his free t may be too high. I also got bad headaches when my free t was high .. I've told him to get bloods done but apart from dropping the gel...

Abstract In humans, testosterone (T), dihydrotestosterone (DHT), estradiol (E2), estrone (E1) and cortisol (C) bind to the serum proteins sex hormone-binding globulin (SHBG), albumin (Alb) and corticosteroid-binding globulin (CBG). Equilibrium dialysis is considered to be the "gold standard" for...

Hey Guys, I received two different sets of free testosterone labs and am trying to make sense of them. The first was LabCorp's Equilibrium FT test and the second was their Direct FT test. What is the difference and which labs would be more accurate in this case? For reference my SHBG is 20 and...

From an article on the study: Risk was estimated using multivariable-adjusted Cox regression in 199,698 male UK Biobank participants. 2-sample Mendelian randomization (MR) analysis of IGF-I and risk used genetic instruments identified from UK Biobank men and genetic outcome data from the...

Hello everyone, I was wondering if I could get some feedback on my thyroid, bun(1st time my bun has been this high, it usually sits at 21), ast, and alt results. Feel free to ask about any other doubts you may have. A quick summary of what I have been doing. I did a 26 week cut and I know when...

Has anyone tried, or can advise on AI monotherapy. My test levels are good but my free test is low, SHBG and est are high (bloods below). I was prescribed 125mg enanthate weekly and HCG 500iu 3 times a week yesterday, however I am extremely concerned about fertility and have decided to think...

Like for example your bloodwork always comes back as around 20% above mid range Total T , but 20% below mid range Free T ?? anything you can do , or just genetics ?

Why does a low Free T % cause symptoms? I calculate 2 profiles. A guy with 600 total T and shbg at 30, and a guy with 800 total T with shbg at 50. Using an online free T calculator, guy 1 has a 2.30% free T and guy 2 has a 1.75%. Both will have similar direct free T numbers of 14 ng/dl. But...

Hi everyone, I'm 32 years old and have secondary hypogonadism (was diagnosed at 25 years old). I've been on clomid for around 7 years now that was prescribed by my urologist. My main question is whether testosterone injections are more effective than clomid for secondary sexual characteristics...