growth hormone

  1. M

    Experience on MK677 and other GH peptides

    Curious on your experience with MK677. Im 27 years old currently taking enclomiphen which has lowered my IGF-1 no suprise there. I am possibly looking into tesamorelin or semorelin but tempted to try MK677 first before going all in on peptide injections. Below are most recent labs taken. My gym...
  2. madman

    Phase 3 pivotal trial design of daily oral LUM-201’s efficacy and safety in treatment-naïve children with GHD in RCT

    * By stimulating endogenous GH release via the GH-releasing hormone pathway and reducing somatostatin activity, LUM-201 preserves the physiological feedback loop, distinguishing it from exogenous GH injections. https://www.endocrine-abstracts.org/ea/0110/ea0110p648 Objectives The...
  3. madman

    Evaluation of the PK, PD, and safety of the new capsule formulation of LUM-201, an oral GH secretagogue

    * The new LUM-201 capsule formulation filled with mini-tablets produces similar PK and PD results compared with the current tablet formulation and offers children & their caretakers a more flexible and user-friendly oral capsule formulation...
  4. Type_IIx

    Should you use T4/T3 with GH? New Article, "GH, Thyroid, and Bodybuilding" by Type-IIx

    GH & THYROID TRUTH BOMBS New Article by @Type_IIx https://ampouletude.com/article/Thyroid-Growth-Hormone-GH-Bodybuilding • T3/T4 preferentially BREAK DOWN muscle • No need for extra thyroid shit • T3 = Muscle killer (WTF?) Learn why thyroid hormones are NOT your friend in...
  5. madman

    Significance of Measuring IGF-1 in Growth Hormone Disorders

    Insulin-like growth factor-1 (IGF-1) plays an important role in the growth and development of the body. Measuring IGF-1 levels assists in growth hormone disorder diagnosis, provides information about growth hormone secretion, and allows for monitoring treatment response. Hear from Dr. Martin...
  6. Nelson Vergel

    Compounded Hormone Products for Men: A Review by Shaun Noorian

    In this conversation, Nelson Vergel and Shaun Noorian discuss the various options available for men's hormonal treatments, focusing on hormone replacement therapy, the role of compounding pharmacies, and the importance of personalized medicine. They explore specific medications such as DHEA...
  7. madman

    Oral Treatment for Rare Disease PGHD

    Rick Hawkins, CEO and Chairman of Lumos Pharma, is developing an oral compound to treat idiopathic pediatric growth hormone deficiency. Currently, the only treatment for this condition is an injection of recombinant growth hormone. The small molecule drug LUM-201 increases the amplitude of the...
  8. madman

    Phase 2 Trial Evaluating LUM-201 for Treatment of Growth Hormone Deficiency

    Pisit “Duke” Pitukcheewanont, MD, Chief Medical Officer for Lumos Pharma, discusses a phase 2 trial evaluating LUM-201 (ibutamoren) for treatment of growth hormone deficiency. Pediatric growth hormone deficiency (PGHD) is a rare condition characterized by insufficient amounts of growth hormone...
  9. madman

    LUM-201’s unique ability to augment the natural pulsatile secretion of GH

    https://investors.lumos-pharma.com/news-releases/news-release-details/lumos-pharma-announces-new-analyses-phase-2-oragrowth212-trial “The new analyses of data from our OraGrowtH212 Trial further characterized LUM-201’s unique ability to augment the natural pulsatile secretion of growth...
  10. madman

    Human Growth Hormone (HGH)

    The ALL ME Podcast is working hard to provide you with information from the World’s leading experts when it comes to all things Appearance and Performance Enhancing Substance related. Throughout the year we ask our listeners to send us topics they’d like to learn more about. Recently we’ve...
  11. madman

    The data and potential of LUM-201 (ibutamoren)

    Andrew Dauber, M.D., Chief of Endocrinology, Children's National Medical Center, Washington, D.C. discusses the data and potential of LUM-201 for children living with moderate pediatric growth hormone deficiency
  12. madman

    Phase 2 OraGrowtH Trials and New Analyses of Oral LUM-201 for PGHD

    https://lifescievents.com/event/lumos-2/
  13. madman

    Revolutionizing Pediatric Growth Hormone Deficiency Treatment

    Rick Hawkins, CEO and chairman of Lumos Pharma, discusses the company’s late-stage development of a small molecule for the treatment of pediatric growth hormone deficiency (PGHD). This innovative oral mini tablet aims to revolutionize the current standard of care, which involves daily injections...
  14. madman

    PGHD and How It Is Managed

    The video discusses pediatric growth hormone deficiency (PGHD) and its management, particularly through daily or weekly growth hormone injections. It explains the diagnosis process, the two categories of patients (moderate and severe), and the different treatment options available, including a...
  15. madman

    LUM-201 (ibutamoren) - The OraGrowtH212 trial

    The OraGrowtH212 trial is a global study involving 80 patients in four arms, testing three different doses of a new drug compared to the standard dose of growth hormone. The study aims to measure catchup growth over an extended period, with promising interim results indicating comparable growth...
  16. madman

    Lumos Pharma Pediatric Endocrinology KOL Panel

    https://lifescievents.com/event/lumos/
  17. madman

    Lumos Hopes Its Oral Alternative to HGH Will Fuel Its Growth

    https://www.iheart.com/podcast/256-rarecast-31040095/episode/lumos-hopes-its-oral-alternative-to-112339601/ Growth hormone deficiency is a rare condition that is the result of inadequate secretion of growth hormone from the pituitary gland. Though recombinant human growth hormone has long been...
  18. madman

    Diagnosing Growth Hormone Defficiency: caveats, & cut-offs

    Growth hormone deficiency (GHD) diagnosis in children and adults is complex due to varying clinical markers and challenges in testing accuracy. GH replacement therapy is crucial for affected patients. Testing requires a thorough medical history, physical examination, and targeted biochemical...
  19. madman

    Revolutionizing Growth Hormone Deficiency Treatment

    LUM 201 (ibutamoren) is a focus of recent research for treating idiopathic pediatric growth hormone deficiency. This rare endocrine disorder, characterized by insufficient growth hormone secretion from the anterior pituitary gland, can manifest at birth, as a result of a medical condition or...
  20. G

    TRT labs

    Just got my labs back, and I'm surprised. I was expecting my numbers to be off. I have been feeling just off, not seeing any progress in my body, and I lift 3–5 times a week. Struggling with weight loss, and I inject only once a week because injecting more than once has always made me fatigue...
  21. T

    Exogenous growth hormone and IGF-1

    Do any of you know.. if one takes exogenous GH, how soon IGF-1 levels drop to baseline after stopping? @Cataceous
  22. T

    IGF-1 and Growth hormone

    Has any one of you guys been on growth hormone and know your pre- and post IGF-1 labs? What source did you go through and did you notice a difference? I found out my IGF-1 is well on the lower end, consistently. But not enough for treatment. @Nelson Vergel @Cataceous
  23. R

    TRT with insomnia

    I have been on TRT for two years now. !00mg/week. Low SHBG 18-22. I am on low dose of Anastrozole .25mg/week say day I take Test cypionate. But I suffer from insomnia, never measured my growth hormone other than IGF-1 which was in normal range. I am not diabetic. I have great energy but I get...
  24. Hormetheus

    I replace all my hormones. Here is what I learned.

    I am new to this group. Thanks for having me. I want to share my journey with hormone replacement because I believe it might be useful to others. My story: I am a medical student in my last year. I replace all of my hormones. In early twenties my life was starting to go down the gutter. My...
  25. M

    Growth hormone affecting sleep apnea and heart rhythm?

    Has anyone else experienced premature ventricular contractions (PVCs) or other ectopic beats once GH is commenced? I've been prone to PVCs over the last couple years in varying frequencies. I take more than enough magnesium as a mainstay and many other supps to support cardio health. I am also...
  26. D

    Hypopituitarism and muscle gains

    Hello everyone, I am a 32 year-old man. I have suffered from hypopituitarism since birth. At the age of 5 I started taking GH and Hydrocortisone. The pediatrician monitored my bone development until I was 17 years old, when she decided that I should stop the GH replacement therapy and start...
  27. C

    Any reason to use hgh as a under 30

    Hello Is there any reason to use growth hormone as under 30 years old? I would like to see what effect it have on my skin , sleep and wellness. Mainly my skin. I ve used pramipexole in a past for high prolactin and thats is known to increase hgh levels temporaly, i got awesome skin results from...
  28. madman

    OFF-LABEL USE AND MISUSE OF T, GH, THYROID HORMONE, AND ADRENAL SUPPLEMENTS

    OFF-LABEL USE AND MISUSE OF TESTOSTERONE, GROWTH HORMONE, THYROID HORMONE, AND ADRENAL SUPPLEMENTS: RISKS AND COSTS OF A GROWING PROBLEM ABSTRACT Over the past few decades, there has been an unprecedented rise in off-label use and misuse of testosterone, growth hormone, thyroid hormone...
  29. G

    How Much Are You Paying for MK-677 - Ibutamoren?

    Anyone using MK-677? If so, how much is it costing you, and what’s your experience with it? Thanks.
  30. G

    Anyone use peptides?

    Interested in Tesamoreli and Ipamorelin. Does anyone use either of those? If so, how much is it costing you? Thanks.
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