Libido

Low libido is one of the most common reasons men turn to TRT, and also one of the most common complaints among men already on TRT who feel physically better but sexually flat. Discussions in this tag explore the multiple drivers: estradiol too high or too low, suppressed DHT, elevated prolactin, HPA-axis effects from long-term suppression, DHEA depletion, and protocol design choices like injection frequency. Members share what worked for them, including HCG addition, scrotal cream or DHT gel trials, PT-141, Cialis daily, and targeted E2 management.
  1. N

    Fsh and libido

    Hi all. My doc says fsh plays a major role in libido. Now I'm in trt and as we know the fsh drops to very low figures. Can having low fsh effect some guys on trt to have no libido like me. I've tried everything and u mean everything over the last few years and since starting trt my libido has...
  2. madman

    One partner wants sex, the other doesn’t

    This ISSM Webinar is on One partner wants sex, the other doesn't: how to handle sexual discordances in otherwise happy relationships. “I want to have sex, but my partner doesn’t, is that normal?” This question and the underlying interpersonal discordance which it illustrates are not only...
  3. J

    Reducing Testosterone Dosage

    I was on 70mg of Testosterone Cypionate twice weekly + 750IU of hCG twice weekly. I was getting a lot of hair shedding and acne. I tried finasteride and got pretty bad ED that persisted after I stopped. I eventually recovered mostly but never fully. I don't need Viagra or anything but never...
  4. O

    How can I drop TT and DHT by a lot and E2 by a little?

    Hey guys, I got some alarming labs back a few weeks ago and am trying to make the right adjustments to my dosing protocol. This is a long post, so I hope it doesn't get ignored. I would really appreciate some help and I'm trying to give you any info that you might need without forcing you to...
  5. madman

    Does Bremelanotide or PT-141 actually Work to Increase Sexual Desire?!

    Have you heard of Bremelanotide or PT-141? Does it work for premenopausal women only? Or is this amazing new drug a new option for erectile dysfunction and low libido for men? Watch the video till the end and let me know your thoughts in the comments. Thanks for watching!! ▶️Chapters...
  6. madman

    Treatments for Low Sexual Desire in Women & Men

    https://www.issm.info/meetings/issm-podcasts/issm-podcast-episode-4 In this episode 4, urologist and Editor-in-Chief of Sexual Medicine Reviews Irwin Goldstein talks about Treatments for Low Sexual Desire in Women & Men hosted by Shelly Varod (Israel), a certified sex therapist with the support...
  7. madman

    Struggling with Low Libido? Little Pink Pill AKA Female Viagra

    Have you heard of the 'Little Pink Pill' also known as the 'Female Viagra'? Did you know that 40% of women experience low libido but only 10% are concerned by it and they are the ones who need this medication called Flibanserin? Watch till the end to know more about its side effects. Let me...
  8. madman

    Evaluation of bremelanotide injection for the treatment of HSDD

    An evaluation of bremelanotide injection for the treatment of hypoactive sexual desire disorder (2022) Sarah Cipriani, Chiara Alfaroli, Elisa Maseroli & Linda Vignozzi ABSTRACT Introduction: Female sexual response implies a deep intertwining between psychosocial and neurobiological...
  9. A

    New here: erections and libido lagging, high BP and lipids

    Hi- Just wanted to thank everyone who shares information here, it's been great to learn, and I thought I would share my story in case it's helpful to anyone. I'm 43 and married. We have a great sex life even with a young child, having sex about twice a week. Together for 12 years, all is good...
  10. T

    Need libido/dysautonomia help please read entirely!

    Was on trt and a super low dose of proviron 12.5 mg a day sometimes 2 x a day. About 120mg test. Felt great for 5 years. Then all of a sudden I got heart racing headaches ect. Symptoms of autonomic dysfunction. So they tried taking me off the test but the lowest I can get to is 20mg a week in a...
  11. madman

    T and Male Sexual Function

    Testosterone and Male Sexual Function (2023) Logan B. Galansky, MD, Jason A. Levy, DO, MS, Arthur L. Burnett, MD, MBA INTRODUCTION Male sexual function involves a complex interplay between hormonal, anatomic, and neuropsychologic functions and mediators. At the basis of any discussion...
  12. G

    Low libido and weak erections - protocol change?

    Hi all, I've been on trt for about 4 years, currently under Dr Saya's care. My libido recently went down dramatically and my erections, which have not been consistently great in years, have gotten much worse recently. They start OK, but 2 minutes later starts getting softer and softer. I'm 34...
  13. C

    High SHBG - any way to lower?

    I recently was able to view lab results from 2018 to present day. Every time I have had lab work done (hormone panel) my SHBG is always higher than it should be. The higher than normal value presented even before I tried self prescribed TRT. 2018 (prior to testosterone) - Testosterone 26.9...
  14. madman

    Questions on Sexual Health - Libido, Arousal, Orgasm & ED

    Dr. Rachel Rubin is a board-certified urologist and sexual medicine specialist. She is an assistant clinical professor of Urology at Georgetown University and owns her private practice in the Washington DC region. She is one of only a handful of physicians fellowship trained in male and female...
  15. Drug350

    6 weeks on TRT - Is there a Honeymoon Phase or Too high a Dose Perhaps ???

    I don't want to make this post too long, so I'll condense as much as possible. 54 yrs old, been feeling shitty for several years. My testosterone came back as follow: Testosterone = 169 NGDL Free Testosterone = 3.1 NGDL Bioavailable Testosterone = 72.6 NGDL SHBG = 34 nmol/L TSH = 2.64 uiU/ml...
  16. R

    TRT Since 2013 - Feeling Worse Than Ever

    Hey guys, I'll be brief, just looking for some feedback. Been on TRT since 2013 due to a testicular injury suffered in the gym. T never recovered past 300 total after surgery, so here I am. First doc was the urologist, 200mg IM every 2 weeks. Felt amazing for like 3 months and then the...
  17. Z

    Feel worse with higher test levels

    I’m seeing a lot more post with people who have test levels above 1000 who feel crappy. Even with everything else in range e2, DHT, prolactin etc. I’ve also have seen post of people almost using microdose amounts and feeling way better. My question is, is this the new thing? Because my doctor...
  18. G

    Libido Lost

    A little background info. I have a pituitary tumor, diagnosed in 2018. Been on TRT since 2019. On thyroid meds, and cortisol is ok. I've been taking HGH .4 once a day for 2 months roughly. Its killing my libido, and I dont understand why. I took HGH a year ago, and the same thing happen, and I...
  19. T

    Low libido - subclinical hypothyroidism? Iodine deficiency?

    Hello, is it possible have low libido and poor erection due to low iodine? And I also have symptoms as hypothyroidism (hair loss, dry skin, cold intolerance, poor memory and concentration)? My blood results: TSH varies from 3.7 to 1.98 (0.350 - 4.94) Ant TG: <15 (0 - 115) FT4: 12.45 (9.01 -...
  20. C

    Just started trans-scrotal cream 3 days ago. How long does it take to notice a difference.

    Hello all, I started on 75mg a day a couple days ago after my labs showed test in the gutter. I know that it takes about 3 weeks to see the first changes from injections but can’t find anything about the cream. I thought this was due to levels having to stabilize as it is an ester, however the...
  21. S

    Pygeum - can it lower libido?

    Is Pygeum worth experimenting with? Libido is already an issue for me and I've been trying to improve it for ages. Since Pygeum decreases DHT I'm guessing it can have harmful effects on my libido. I did notice great effects from an alpha blocker - Doxazosin. Thoughts on adding Pygeum to the...
  22. N

    Semax for libido

    I have recently been watching vigorous Steve talk about semax and how good it was for his libido .. has anyone used this and had libdio enhancing effects?
  23. C

    Libido Supplements

    I have posted on this board in the past regarding TRT and libido. I had briefly dabbled with self prescribed TRT a few years back. It was initially amazing (honeymoon) with regards to energy and libido but that quickly paled in the face of the negative sides I experienced. I ultimately stopped...
  24. madman

    Hormone facts that will explode your brain

    Dr. Ashley Winter, Chief Medical Officer of Odela discusses important facts about hormone levels, and what you can do to treat deficiencies in estrogen levels.
  25. madman

    Testosterone and Sexual Desire

    Testosterone and Sexual Desire: A Review of the Evidence (2022) Vi Nguyen, MD,* Austin Leonard, BA, and Tung-Chin Hsieh, MD Abstract Sexual desire is driven by complex interactions between various biopsychosocial factors including neuroendocrine regulation, mental state, and cultural values...
  26. madman

    Women's Sexual Health, Men's ED, and More

    I recently had the pleasure of interviewing urologist and sexual health expert, Dr. Rachel Rubin. Hear Dr. Rubin break down too often ignored subjects like women's painful sex, and men's erectile dysfunction.
  27. madman

    Sexual Health with Dr. Rachel Rubin

    Today we have a special guest with us! Listen in as host, Dr. Carolyn Moyers is joined by Dr. Rachel Rubin, a board-certified urologist, and sexual medicine specialist. She is one of only a handful of physicians with fellowship training in sexual medicine for all genders! Dr. Rubin is...
  28. M

    Stopped HCG, better libido and daily morning wood.

    As all of you I am still looking for the best protocol. I consistently noticed everytime instop HCG I see increase in libido. Currently I went off hcg and it’s been one and half month almost two month. Consistent morning wood and increased libido.finishing the job not easy yet all other...
  29. T

    Proviron vs DHT gel?

    Hi, Firstly to introduce myself I’m 34 years old and have been on TRT now for 1 year at a dosage of 100mg Test E twice weekly. Feeling overall good during this time however my libido and erectile function could be better. Recent bloodwork shows my DHT levels to be slightly below midrange even...
  30. B

    Iron on TRT? - No libido

    26m who has struggled on TRT for a long time. In summer 2021 was prescribed test cypionate which immediately causes complete loss of libido, which only returned about 6 weeks after cessation of treatment. Testosterone did not naturally recover (although libido did), and resumed treatment this...
  31. L

    Symptoms of Low T Except Libido and Erections Still Good

    Hello All, About 6 months ago I started weight training with body trainer. He said I was one of his hardest working clients but noticed I was not making muscle. He said it would be a good idea to get T tested. I read up more on low T issues and sure enough I have some symptoms: Insomnia...

Libido

Libido Low libido is one of the most common reasons men turn to TRT, and also one of the most common complaints among men already on TRT who feel physically better but sexually flat. Discussions in this tag explore the multiple drivers: estradiol too high or too low, suppressed DHT, elevated prolactin, HPA-axis effects from long-term suppression, DHEA depletion, and protocol design choices like injection frequency. Members share what worked for them, including HCG addition, scrotal cream or DHT gel trials, PT-141, Cialis daily, and targeted E2 management.

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