weight loss

Semaglutide, sold as Ozempic and Wegovy, and tirzepatide, sold as Zepbound and Mounjaro, are new therapies for weight loss that actually work, helping millions around the world to feel better. But some people are fearful of side effects, such as loss of muscle mass. Are their fears warranted...

Truly impressive! * the really exciting data of SYNCHRONIZE-1 was not the weight loss it was actually the metabolic health gains so we see that there was an improvement in glycemia and blood pressure but there was a. 63% REDUCTION IN FAT IN THE LIVER so imagine you had 16% weight loss but 25%...

Hey everyone, glad to be here. I’ve been deep-diving into peptides lately and honestly became a little obsessed with learning about them lol. Started out just reading about recovery and performance compounds like BPC-157 and TB-500, then somehow ended up spending hours going through discussions...

Been on it for 15 weeks. Lost 15LBS so far. Wanted to try trizep but $$$$$$$ :( Insurance mail order covered the Liraglutide. I seem to hit some plateaus for a week or so then weight starts back down again. Then plateau then down slowly. From looking around this section my weight loos seems to...

In this episode of Science Quickly, Scientific American’s associate health editor Lauren Young joins host Kendra Pierre-Louis to talk about how the story of GLP‑1 drugs such as Ozempic, Wegovy and Mounjaro is evolving. We trace GLP-1s’ origins as type 2 diabetes treatments, their rise as...

Are GLP-1 agonists like Ozempic and Mounjaro the future of healthcare or a risk to your health? We break down the latest data on weight loss medication efficacy, common side effects, and the truth about muscle mass loss (sarcopenia). In This Episode: Dr. Jordan Feigenbaum and Dr. Austin...

What actually makes a GLP-1 pill work in the real world—and why does taking it come with such specific rules? And if these meds improve health beyond weight, why does the conversation still get stuck on the scale?Dr. Emily Cooper, Mark Wright, and Andrea Taylor sit down with Novo Nordisk’s Dr...

Bariatric Surgery Males Bariatric surgery significantly influenced sex hormone levels in males. Estradiol (E2: Hedges’ g = − 0.90, 95% CI [− 1.30, − 0.50], P < .001), dehydroepiandrosterone (DHEA: Hedges’ g = − 0.50, [− 0.85, − 0.15], P = .005), and prolactin (PRL: Hedges’ g = − 0.30, [− 0.60...

* we discuss what a recently rolled-out GLP-1 pill, the first of its kind approved for obesity, could mean for the future of weight loss. Drugs known as glucagon-like peptide-1 receptor agonists, colloquially called GLP-1 medications, have gone from relatively obscure diabetes...

Had my physical last week. My PCP loved my labs and vitals but said I'm fat. She acknowledged my hard earned muscle but feels I should drop some fat (5'11" and 227 pounds). I told her at my age (60) it's been a struggle. I used to be able to drop weight easily. I'm not blaming my age, I'm...

In this episode, Dr. Spencer Nadolsky discusses the transformative role of GLP-1 medications in obesity treatment. He explains the mechanism of GLP-1, its rise in popularity, associated risks, and the importance of personalized medicine. The conversation also touches on the significance of...

* The anticipated lower cash price – reported at approximately $149 – could substantially improve access, particularly compared with injectable GLP-1–based weight loss therapies. The hosts discuss patient preferences, noting that an oral option may appeal to individuals hesitant about injections...

I have not had very good experiences with GLP-1 drugs. The appetite suppression was nice, but the gastrointestinal side effects were a deal breaker. Semaglutide and Tirzepatide both shut down my digestive system. My wife has been on Retatrutide for a few months with very good results. I need to...

Takeaway Messages

56M and am struggling with low Testosterone (Total) 195.00 ng/dL, low free T (Free Testosterone (Direct MS Assay) 24.50 pg/mL (poor cut off is 3.7)), depressed Estradiol (from 2021 – but no recent score) and moderately high SHBG (SHBG 52.00 nmol/L). FSH and LH are normal. My lipids (Total...

In this episode of You Are Not Broken, Dr. Kelly Casperson sits down with endocrinologist and obesity medicine expert Dr. Rocio Salas-Whalen for a deep dive into GLP-1 medications (like Ozempic, Wegovy, and Mounjaro). They cover everything you should be asking but probably haven’t heard...

This is all new to me , what could you stack with TRT to help with weight loss and muscle gain ? I have high BP and high cholesterol and I wanna get off that stuff!

I was diagnosed with Fatty Liver back in 2017, however my testosterone was dropping alongside of it ! I spoke to my pcp about the issues I was seeing and having and asked if I could be placed on TRT. His short but quick answer was absolutely not! He gave me multiple reasons with many other...

* Erectile Dysfunction = ENDOTHELIAL DYSFUNCTION Wearable Penile Devices: Past, Present, and Future - John P. Mulhall, MD, MSc, FECSM, FACS, FRCSI Take Home Messages

In todays Wall Street Journal an interesting read about weight loss drugs and sports performance.............. https://www.wsj.com/health/wellness/ozempic-amateur-athletes-3fc9e0bf?st=jgBnBU&reflink=article_email_share

https://www.urologytimes.com/view/pearls-perspectives-urology-role-in-glp-1-ra-treatments-with-hossein-sadeghi-nejad-md-and-nathalie-eid-ba In this 2-part episode of Pearls and Perspectives from the American Urological Association's (AUA) 2025 Annual Meeting in Las Vegas, NV, host Amy Pearlman...

https://www.cnbc.com/2025/04/25/novo-nordisk-legal-win-bars-many-compounded-wegovy-ozempic-drugs.html Key Points Novo Nordisk scored a huge legal victory that largely restricts compounding pharmacies from marketing or selling cheaper, unapproved versions of the drugmaker’s blockbuster weight...

The guest speakers says it all LOL! The Obesity Society (TOS) convened a panel of leading experts in obesity medicine, pharmacy, and regulatory law on March 19, 2025, to discuss the growing concerns surrounding the use of compounded GLP-1s for weight management and diabetes treatment. The...

I just found out about the whole ban on compounded tirzepatide (I been living under a rock apparently). My provider presents these options to me now: Empower Pharmacy (Tirzepatide/Niacinamide) Strive (Tirzepatide/Glycine/B12) Southend Pharmacy (Tirzepatide/B6) Red Rock (Tirzepatide/Glycine) I...

Ross Arena, PhD, Professor and Head of the Department of Physical Therapy, College of Applied Health Sciences, at the University of Illinois at Chicago, reviews his article appearing in the December 2024 issue of Mayo Clinic Proceedings, where he finds promise in the newly emerging medical...

Chapters: 0:00—Introduction to GLP-1 Drugs 08:48—Obesity as a Major Health Concern 11:52—Diabetes: The Original Indication for GLP-1 15:26—Cardiovascular Implications of GLP-1 20:16—Kidney Health and GLP-1 Mechanisms 24:02—Exploring GLP-1 Effects on Mental Health 29:27—Challenges and Side...

Weight Loss Could Be Key to Male Infertility: What the Research Says There's some exciting news for men struggling with infertility and obesity—losing weight could make a big difference. For the first time, research shows that shedding extra pounds not only improves general health but can also...

Tirzepatide and semaglutide are both injectable medications used for weight loss and type 2 diabetes management, but they differ in their mechanisms of action and effectiveness. Here's a comparison of the two drugs: Mechanism of Action Tirzepatide: Dual glucose-dependent insulinotropic...

https://www.vumedi.com/video/aua-2024-insights-glp-1-receptor-agonists-and-mens-health/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011940/?fbclid=IwAR2tVliRNZld3ui2Kp70UeUrWFWsRaG5vphx8EF13fdB4aUn-vBc0v1aEKY_aem_AbqXSwyVpOvYCcYGlesCJW4UniV_Gzu02SPO3aX-qfs_8EF0ogIva-jCpe-_fAOuAmA#:~:text=In%20conclusion%2C%2024%2Dweek%20treatment,induced%20improvement%20of%20glycemic%20control

Dr. Carolyn T. Bramante, MD, MPH presented a grand round on Anti-Obesity Pharmacotherapy for Long-Term Obesity Management. She discussed the complexity of obesity as a disease, the physiological and genetic factors affecting it, the importance of individualizing treatment, and the effectiveness...