Started now i want to quit

Markspark

New Member
Hi I’m Mark 56 years of age and appreciate bring able to discuss my situation with you experienced people
I started going through divorce in January, 2025 I’m at the end of 2025. I started getting very stressed over it all and was thinking maybe my testosterone levels were low, I have had a super healthy diet for over 20 years now no alcohol no smoking a steak every day eggs every day row Keffer raw milk and so on just to give you a picture of myself and I am low body fat, so I went to a local clinic in the UK to get tested and this was the result picture attached
The clinic I’m using suggested I start TRT and I know I should’ve done more research but it’s too late for that now so I started eight weeks ago on 125 mg weekly of sustanon and I know it’s early days but I’m not feeling it and I wanna stop now before I do my natural testosterone production any more damage but I am in a dilemma. I am going on holiday in four weeks with my daughter and grandchildren, if I stop this TRT now which as I said I have had eight weeks so far eight injections of 125 mg a week. How hard when it hit me if I go cold Turkey or what do you advise? Help much appreciated
 

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I would just stop. Your natural production will likely begin to return within 4 to 6 weeks. Because 8 weeks is a relatively short duration.
 
Hi I’m Mark 56 years of age and appreciate bring able to discuss my situation with you experienced people
I started going through divorce in January, 2025 I’m at the end of 2025. I started getting very stressed over it all and was thinking maybe my testosterone levels were low, I have had a super healthy diet for over 20 years now no alcohol no smoking a steak every day eggs every day row Keffer raw milk and so on just to give you a picture of myself and I am low body fat, so I went to a local clinic in the UK to get tested and this was the result picture attached
The clinic I’m using suggested I start TRT and I know I should’ve done more research but it’s too late for that now so I started eight weeks ago on 125 mg weekly of sustanon and I know it’s early days but I’m not feeling it and I wanna stop now before I do my natural testosterone production any more damage but I am in a dilemma. I am going on holiday in four weeks with my daughter and grandchildren, if I stop this TRT now which as I said I have had eight weeks so far eight injections of 125 mg a week. How hard when it hit me if I go cold Turkey or what do you advise? Help much appreciated

Addressing your suspicion of low-T was a smart move as your TT 265 ng/dL is at the bottom end and far from healthy.

Even then although TT is important to know FT is what truly matters here as it is the active unbound fraction of T responsible for the positive effects.

The only way to know where your FT truly sits would be testing it using the most accurate assay the gold standard Equilibrium Dialysis especially in cases of altered SHBG.

If you do not have access to such which would be more common if you live outside of the US then you would. need to use/rely on the next best testing method the go to calculated linear law-of-mass action Vermeulen (cFTV).

Seeing as you are living in the UK your FT was most likely tested using the calculated method and as you can see it is sitting on the bottom end of the reference range.

You can easily calculate your FT using the cFTV online as it is available for free to the general public.

Just need to plug in your TT, SHBG and Albumin.

If we take your bottom end TT 265 ng/dL, normal SHBG 30.7 nmol/L and Albumin 4.3 g/dL (default) as you never had it tested then your cFTV 5.39 ng/dL it sitting right at the bottom end.


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Even then keep in mind that cFTV tends to overestimate slightly so if you had it tested using the gold standard ED assay it would most likely be lower as in <5 ng/dL.

Regardless your FT is dismal and far from what would be considered healthy.

Most healthy young natty males would be hitting a cFTV 13-15 ng/dL or a FT 12 ng/dL tested using the gold standard ED assay.

Just to put this in perspective!

FT <5 ng/dL would be considerd low.

FT 5-9 ng/dL would be considered the grey zone where some men may experience symptoms of low-T.

FT 10-15 ng/dL would be healthy.

FT 20-25 ng/dL would be high-end/high!

The majority of men will do well with a trough FT 15-25 ng/dL depending on the injection frequency.

Again your FT is low and seeing as you are 56 and are still in descent shape, eat healthy and avoid some of those bad habits your FT is not going to get any better.

Lack of quality sleep, exercise, excess stress (physical/mental) and excess body fat can easily hammer down your natty T but even then you have addressed some of the things which can have a negative impact.

Getting quality sleep and minimizing excess stress (mental/physical) is critical here.

Seeing as you have been injecting 125 mg T (mixed ester) for 8 weeks your HPG-axis is already suppressed as your LH/FSH will be next to nil.

Not sure why you want to stop therapy as you will just go back to baseline once the exogenous T is out of your system and you will end up struggling with low-T symptoms which is a shitty situation to deal with and more importantly you are at a huge disadvantage here when it comes to your overall health (mental/physical) especially cardiovascular and bone health.

More importantly, its metabolites estradiol and DHT are needed in healthy amounts to experience the full spectrum of testosterone-beneficial effects on (cardiovascular health, brain health, libido, erectile function, bone health, tendon health, immune system, lipids, and body composition).

*Natural testosterone is viewed as the best androgen for substitution in hypogonadal men. The reason behind the selection is that testosterone can be converted to DHT and E2, thus developing the full spectrum of testosterone activities in long-term substitution

You quality of life is what matters here and addressing your low-T would improve your overall health especially long-term.

If anything I would wait until after your vacation to stop otherwise you are going to experience a crash if you stop now once the exogenous T is out of your system.

This can be a very bumpy ride for some when stopping cold turkey and chances are you will struggle mentally and physically (energy, mood, libido, erectile function).

Yes some men will just bite the bullet and deal with it whereas others would implement a light PCT using a SERM (clomid/emclomiphene) and hCG.

Even though you have only been injecting 125 mg T (mixed ester) for 8 weeks the T will still be in your system for a few weeks due to the PK.

Once your T levels get closer to bottoming out you will start to feel the negative effects.

The last thing you want to do here is run into low-T when you are planning on a vacation with your daughter and grandchildren.

You deserve to enjoy this precious time with them.

What issues are you experiencing that makes you want to throw in the towel 8 weeks in?
 
Thankyou so much madman for that detailed reply and clearly reading my post fully, there are a few things really, I’m not sleeping any better since starting the treatment 8 weeks ago, i am getting like 3 hours decent ish sleep and 3 hours half decent sleep on my best nights, my libido is probably worse than before i started, i don’t feel as healthy as i did before i started, im hungry all the time, i look more tired than i did before i started, im just not feeling great, when i had my bloods done at the clinic i was chronically stressed from over thinking my divorce and having to sell the marital home etc, so i guess my t would have been low due to that and when i had my bloods done at the doctors last year my serum testosterone was 14.6 nmol see pics, it won’t let me post a pic because i can’t post links so i will try on a separate post
 
My bloods were done at 6 weeks i have been messaging the guy for 2 days to send them over to me, i was thinking maybe i should be on cypionate of enanthate instead of sustanon and maybe injecting twice a week, but i feel so shit i thought it might be easier just to stop
 
My bloods were done at 6 weeks i have been messaging the guy for 2 days to send them over to me, i was thinking maybe i should be on cypionate of enanthate instead of sustanon and maybe injecting twice a week, but i feel so shit i thought it might be easier just to stop

6 weeks in is too early as you have not even achieved steady-state due to the PK.

Keep in mind due to the longest acting ester (decanoate) in the Sustanon formulation it will take longer to reach steady-state vs the medium acting esterified TE or TC.

Most commonly used esters especially in Canada/US are TE or TC and steady-state is achieved 4-6 weeks due to the PKs.

When are you due for blood work?

Most likely 3 months in.

We would need to see where your trough (lowest point) before your next injection has your TT and more importantly FT, estradiol, SHBG and critical blood markers RBCs, hemoglobin and hematocrit.

Seeing as you re injecting once weekly your true trough would be 7 days post-injection.

Keep in mind when first starting TTh or tweaking a protocol the weeks leading up until blood levels have stabilized mean nothing when looking at the bigger picture here as your hormones will be in flux during the weeks leading up until steady-state is achieved and it is common for one to experience ups/downs along the way as the body is trying to adjust to the increase in T and its metabolites (estradiol/DHT).

Many tend to experience what is called the honeymoon period where one feels euphoric, increased libido and erections and overall well-being due to increased dopamine, rising T and lighting up of the ARs (androgen receptors).

Unfortunately this is short-lived and temporary as the body will eventually adapt and things tend to wane back in the norm as in healthy.

Even then once steady-state is achieved it will still take the body time as in a few more months to adapt to its new set-point and this is the critical time period where one needs to gauge how they truly feel overall regarding relief/improvement of low-T symptoms and overall well-being.

When using TE or TC it will take 4-6 weeks to reach steady-state so the first 4-6 weeks means nothing when looking at the bigger picture here as the body is trying to ADJUST to the rising T.

Once steady-state is achieved it will take a few more months for the body to ADAPT to its new set-point.

Every protocol needs to be given a fighting chance at least 12 weeks before claiming whether it was a success or failure.

Even then keep in mind the ADJUSTMENT phase when using Sustanon will take longer due to the PK as one of the esters (decanoate) used in the formulation is longer acting than TE/TC.

Remember you are only 8 weeks in!
 
6 weeks in is too early as you have not even achieved steady-state due to the PK.

Keep in mind due to the longest acting ester (decanoate) in the Sustanon formulation it will take longer to reach steady-state vs the medium acting esterified TE or TC.

Most commonly used esters especially in Canada/US are TE or TC and steady-state is achieved 4-6 weeks due to the PKs.

When are you due for blood work?

Most likely 3 months in.

We would need to see where your trough (lowest point) before your next injection has your TT and more importantly FT, estradiol, SHBG and critical blood markers RBCs, hemoglobin and hematocrit.

Seeing as you re injecting once weekly your true trough would be 7 days post-injection.

Keep in mind when first starting TTh or tweaking a protocol the weeks leading up until blood levels have stabilized mean nothing when looking at the bigger picture here as your hormones will be in flux during the weeks leading up until steady-state is achieved and it is common for one to experience ups/downs along the way as the body is trying to adjust to the increase in T and its metabolites (estradiol/DHT).

Many tend to experience what is called the honeymoon period where one feels euphoric, increased libido and erections and overall well-being due to increased dopamine, rising T and lighting up of the ARs (androgen receptors).

Unfortunately this is short-lived and temporary as the body will eventually adapt and things tend to wane back in the norm as in healthy.

Even then once steady-state is achieved it will still take the body time as in a few more months to adapt to its new set-point and this is the critical time period where one needs to gauge how they truly feel overall regarding relief/improvement of low-T symptoms and overall well-being.

When using TE or TC it will take 4-6 weeks to reach steady-state so the first 4-6 weeks means nothing when looking at the bigger picture here as the body is trying to ADJUST to the rising T.

Once steady-state is achieved it will take a few more months for the body to ADAPT to its new set-point.

Every protocol needs to be given a fighting chance at least 12 weeks before claiming whether it was a success or failure.

Even then keep in mind the ADJUSTMENT phase when using Sustanon will take longer due to the PK as one of the esters (decanoate) used in the formulation is longer acting than TE/TC.

Remember you are only 8 weeks in!
I don’t mind sticking to the trt but i don’t want to feel worse, should i ask him to put me on cypionate once a week starting next week or stick with the sustanon
 
Thankyou so much madman for that detailed reply and clearly reading my post fully, there are a few things really, I’m not sleeping any better since starting the treatment 8 weeks ago, i am getting like 3 hours decent ish sleep and 3 hours half decent sleep on my best nights, my libido is probably worse than before i started, i don’t feel as healthy as i did before i started, im hungry all the time, i look more tired than i did before i started, im just not feeling great, when i had my bloods done at the clinic i was chronically stressed from over thinking my divorce and having to sell the marital home etc, so i guess my t would have been low due to that and when i had my bloods done at the doctors last year my serum testosterone was 14.6 nmol see pics, it won’t let me post a pic because i can’t post links so i will try on a separate post

Yes this is a shitty situation especially when it comes to getting quality sleep as lack of sleep let alone chronic stress (physically/mentally) will drain you of energy, have a negative impact on your mood and overall health especially cardiovascular and hammer down your libido/destroy erections.

When it comes to testing TT/FT/BAT hope you understand that you need to test at the peak in the early am in a fasted state otherwise your results would be skewed.

Did you test at peak (early am) in a fasted state?

I see your labs results from post #8 which still had you hitting a shitty natty TT 10.3 nmol/L or 297 ng/dL which means your cFTV 6.1 ng/dL would have still been dismal and your TT 14.6 nmol/L or 421.1 ng/dL is much better but your cFTV 9.0 would still fall in what would be called the grey zone 5-9 ng/dL where some men may experience symptoms of low-T.

Even then your FT would still be sitting well under where a healthy young natty males cFTV 13-15 ng/dL sits.

If you felt better overall with a FT that falls in the grey zone before you jumped on T then do what you feel is best for you.

Without lab work tested at steady-state on the Sustanon protocol 125 mg T/week we are shooting in the dark here as we have no idea where your trough TT and more importantly FT, estradiol and SHBG sits.

You would have most likely fared much better using esterified TE or TC.

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I don’t mind sticking to the trt but i don’t want to feel worse, should i ask him to put me on cypionate once a week starting next week or stick with the sustanon

If you decide to stick with it which is most likely the most sensible move as your natty T and more importantly FT is far from healthy then I would switch over to TE if you can get it otherwise go with TC.

Start on 100 mg TE/TC split twice-weekly (50 mg T).

Blood work will be done 6 weeks in once you have achieved steady-state.
 
Thankyou Do you think i will feel bad in 4 weeks for my holiday
You may feel bad. Normally, at least the people I know that stopped TRT. They recover pretty quickly, I would continue having sex and continue exercising even if it's just walking. A close friend of my stop after many years of TRT. He recovered quickly and never had any issues. I was really surprised.
 
I don’t mind sticking to the trt but i don’t want to feel worse, should i ask him to put me on cypionate once a week starting next week or stick with the sustanon

Your reply from earlier this morning is not showing up!

Did you end up deleting it?


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If you decide to stick with it which is most likely the most sensible move as your natty T and more importantly FT is far from healthy then I would switch over to TE if you can get it otherwise go with TC.

Start on 100 mg TE/TC split twice-weekly (50 mg T).

Blood work will be done 6 weeks in once you have achieved steady-state.
Ok i started on 75mg cyp twice a week had my first shot today, let’s see how we go hopefully onwards and upwards, im not interested in building muscle i just want to sleep good, feel good and have healthy labido
 
I have another question does TRT help you sleep better?

Some of the symptoms of low-T such as fatigue, anxiety/nervousness, low mood/mild depression/anhedonia and in some cases when levels become extremely low night sweats can all have a negative impact on sleep quality.

Having healthy hormones is critical especially when it comes to mental well-being.

Every symptom can be improved when your hormones are healthy but keep in mind there is a catch 22 here as too high a FT can cause issues for some as testosterone has a tonic effect on the CNS which can make on feel amped up or in some cases irritable/agitated which can have a negative impact on sleep quality.

Also keep in mind some men that have risk factors ca be more prone to developing obstructive sleep apnea which will wreak havoc on sleep quality and stress your cardiovascular system.

High-dose testosterone can exacerbate or cause new obstructive sleep apnea (OSA) and this is a bad mix when it comes to elevated hematocrit.

Most sensible move here when it comes to therapy is starting low and going slow as we want to see how your body reacts to testosterone and where said protocol (dose of T/injection frequency) has your trough TT and more importantly FT, estradiol, SHBG and critical blood markers RBCs, hemoglobin and hematocrit.

There will always be time to increase the dose if need be.

Jumping in head first is the last thing you would want to do here.

Trust me when I tell you going up is much easier than having to come down and this can easily be avoided by starting low and going slow eventually titrating if need be until you find that groove.
 
Ok i started on 75mg cyp twice a week had my first shot today, let’s see how we go hopefully onwards and upwards, im not interested in building muscle i just want to sleep good, feel good and have healthy labido

Hope you mean 75 mg T split twice-weekly which would be a sensible starting dose.

Personally I would have went with 100 mg T split (50 mg every 3.5 days) as this is the most common starting dose by those in the know.

Yes there is nothing wrong with starting on <100 mg T/week especially when split into more frequent injections if you feel more comfortable taking that route!




 
I was on TRT the first time for 8 years, came off and my natural production came back quickly and I’m in my 50s. Being on TRT rarely permanently damages your natural testosterone production. If it were to happen, it was likely already headed in that direction anyways.
 
Moved this thread over here!


 

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