The Missing Piece in Erectile Dysfunction: The Fibroblast as an Emerging Therapeutic Target

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The Missing Piece in Erectile Dysfunction: The Fibroblast as an Emerging Therapeutic Target by Dr. Eduardo Guimaraes, Research Specialist, Karolinska Institutet, Stockholm

 

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The corpora cavernosa and its different cell types

The penis contains a LARGE POPULATION of CORPORA CAVERNOSA FIBROBLASTS

 

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The human corpora cavernosa presents a DIVERSE FIBROBLAST POPULATION

Erectile dysfunction CC presents a UNIQUE DISEASE-ASSOCIATED FIBROBLAST

What makes a DISEASE-ASSOCIATED FIBROBLAST UNIQUE?

 

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ED corpora cavernosa DOMAIN DYSREGULATION

ED corpora cavernosa INCREASE FIBROBLAST TO MACROPHAGE SIGNALING

 

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Potential as THERAPEUTIC TARGET DISCOVERY