what should i take to have long term cognitive benefits and have overall stronger baseline?

iwantbetter · Sep 6, 2026

I have pretty severe adhd and unfortunately medication doesn’t work particularly well for me. I am also in a demanding job and want to maximise my performance. what options do I have?

I have also looked into things like NSI-189 and ACD 856 but these seem to involve cycling and it is not something I want to have to take forever just to function. I am more interested in finding something that could provide longer term cognitive benefits after taking it for a period of time ideally, rather than something I would need to rely on indefinitely

now, does it exist? I understand the limitless pill is a myth but i just want a good performance in my workplace and not worry about losing income.

Guided_by_Voices · Sep 6, 2026

iwantbetter said:
I have pretty severe adhd and unfortunately medication doesn’t work particularly well for me. I am also in a demanding job and want to maximise my performance. what options do I have?

I have also looked into things like NSI-189 and ACD 856 but these seem to involve cycling and it is not something I want to have to take forever just to function. I am more interested in finding something that could provide longer term cognitive benefits after taking it for a period of time ideally, rather than something I would need to rely on indefinitely

now, does it exist? I understand the limitless pill is a myth but i just want a good performance in my workplace and not worry about losing income.

Lithium and Saffron are two things you could consider. Modafanil is something I am less familiar with but it might help as well and I think there is a recent podcast by Dave Asprey solely devoted to it. Mod.com is a possible source but I've never used it.

iwantbetter · Sep 7, 2026

Guided_by_Voices said:
Lithium and Saffron are two things you could consider. Modafanil is something I am less familiar with but it might help as well and I think there is a recent podcast by Dave Asprey solely devoted to it. Mod.com is a possible source but I've never used it.

I have tried modafanil in various dosages but i find it makes me really jittery and anxious, i am looking for something stronger than standard supplements and experimental

Nelson Vergel · Sep 7, 2026

You may want to download the PDF in the first post of this 2-page thread:

Thread 'List of Nootropics: Brain supplements and medications to increase focus and mood.'

May 23, 2015

Nootropic is a term for a supplement that is ingested primarily for its effects on the brain. Many supplements that are touted to increase cognition, focus, alertness, or well being are grouped under this vague blanket statement.

Here is a spreadsheet on each one (attached PDF)