aging

Starting around age 30, we all begin to lose muscle mass and strength. For some, this progresses into sarcopenia, a condition that can reduce independence, increase disability, and heighten risks of falls, hospitalizations, and other health complications. Joining us to discuss how to prevent...

In this interview renowned exercise physiologist and gerontology expert Dr. Stuart Phillips from McMaster University shares cutting-edge insights into optimizing exercise and nutrition for healthy aging. Dr. Phillips, who has spent decades researching muscle physiology and aging, breaks down the...

From my neck of the woods. Dr. Mark Tarnopolsky is a world-renowned expert in mitochondrial health, muscle function, and ageing science. As a clinician-scientist at McMaster University, he has dedicated his career to understanding how we can optimise our mitochondria - the tiny...

ABSTRACT Creatine monohydrate supplementation (CrM) is a safe and effective intervention for improving certain aspects of sport, exercise performance, and health across the lifespan. Despite its evidence-based pedigree, several questions and misconceptions about CrM remain. To initially address...

Couplepause and Doublepause: Innovative Therapeutic Approaches Couplepause refers to a diagnostic and therapeutic approach that considers the sexual health needs of both partners in an aging couple, rather than focusing on individuals separately. It aims to address shared sexual health issues...

Organic male hypogonadism due to irreversible hypothalamic–pituitary–testicular (HPT) pathology is easily diagnosed and treated with testosterone-replacement therapy. However, controversy surrounds the global practice of prescribing testosterone to symptomatic men with low testosterone and...

What do all women AND men need to know about sex after 50? A huge topic that is seldom discussed by anyone - sex and vaginal health! Dr. James Simon, board-certified ob/gyn and internationally acclaimed Women’s Sexual Health Expert, candidly addresses the questions so many are hesitant to ask...

Many people in the anti-aging world have heard of the experiments done by the team of Mike and Irina Conboy which involved putting the blood from young mice into old mice and vice versa. In summary it showed that the old mice showed signs of getting younger and the young mice showed signs of...

https://podcasts.apple.com/gb/podcast/muscle-protein-and-aging-with-dr-stuart-phillips/id509969439?i=1000645319227 Professor Phillips is a Tier 1 Canada Research Chair in Skeletal Muscle Health in Aging. He is a Professor in Kinesiology, and Graduate Faculty in the School of Medicine at...

Nutrients . 2024 Feb 9;16(4):496. doi: 10.3390/nu16040496. Magnesium and the Hallmarks of Aging Ligia J Dominguez 1 2, Nicola Veronese 2, Mario Barbagallo 2 PMID: 38398820 DOI: 10.3390/nu16040496 Abstract Magnesium is an essential ion in the human body that regulates numerous physiological...

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Hi, new guy here. After years of trying to combat declining T with diet, fat loss, weightlifting, etc. I finally decided to give TrT a try. At 73 years of age my T had been slowly declining to where I recently got the following report: T=328, SHBG=54.7, Free T = 4.63, Albumin 4.4. In...

I wake up with an erection at 3am every morning, rock hard.. Usually have to masturbate to get some sleep.. Would i be better off training at this testosterone peak at 3am or battling to get back to sleep and ignore it and continue to train around mid morning or evenings... 49 year old male on...

Creatine supplementation shows potential benefits for brain health and function, particularly in aging adults and during metabolic stress. It improves cognition, memory, and health outcomes associated with conditions like muscular dystrophy, traumatic brain injury, depression, and anxiety...

Testosterone, other androgens, and selective androgen receptor modulators (SARMs) are being developed to treat age-related functional limitations and chronic diseases. Testosterone treatment increases lean body mass, muscle strength, power, aerobic capacity, and mobility in various populations...

Growth Hormone and Aging (2023) Camille Hage, MD, MPH, Roberto Salvatori, MD BACKGROUND The number of people aged 60 and older outnumbers children younger than 5 years.’ For the first time in history, life expectancy exceeds 60 years worldwide.' The United Nations General Assembly has...

Male Reproduction and Aging (2023) Maria Gabriela Figueiredo, MD, Thiago Gagliano-Jucá, MD, PhD, Shehzad Basaria, MD INTRODUCTION Aging of humans is associated with functional alterations at all levels of the reproductive axis and affects both steroidogenic and spermatogenic compartments...

Osteoporosis Review of Etiology, Mechanisms, and Approach to Management in the Aging Population (2023) Sonali Khandelwal, MD,Nancy E. Lane, MD Osteoporosis, the most common metabolic bone disease, is characterized by low bone mineral density (BMD) and reduced bone strength, and this results...

Supplementing with creatine is very popular amongst athletes and exercising individuals for improving muscle mass, performance, and recovery. In this great talk, Prof. Jose Antonio, Ph.D. (Nova Southeastern University, USA), Prof. Scott Forbes, Ph.D. (Brandon University, Canada), and Prof...

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Prof. Stuart Phillips, Ph.D. (McMaster University) ‘Mitochondrial Health: A key to Aging & Recovering Well' presentation at the American College of Sports Medicine (ACSM) annual meeting 2022. 2:40 - Sarcopenia: the age-related decline in muscle mass, strength, and function 4:41 - Declines in...

Imagine a pill that reduced the risk and improved prognosis for all known chronic diseases; it would work regardless of current risk, race, gender, or age. We don't need to test this pill as a large body of data shows its effectiveness. Other beneficial side effects of this pill include reduced...

Beyond Erectile Dysfunction: cGMP-Specific Phosphodiesterase 5 Inhibitors for Other Clinical Disorders (2022) Arun Samidurai, Lei Xi, Anindita Das, and Rakesh C. Kukreja Abstract Cyclic guanosine monophosphate (cGMP), an important intracellular second messenger, mediates cellular functional...

Male sex hormones, aging, and inflammation (2023) Justin M. Ketchem · Elizabeth J. Bowman · Carlos M. Isales Abstract Adequate levels of androgens (eugonadism), and specifically testosterone, are vital compounds for male quality of life, longevity, and positive health outcomes. Testosterone...

Aging and androgens: Physiology and clinical implications (2022) Bradley D. Anawalt · Alvin M. Matsumoto Abstract In men> ~35 years, aging is associated with perturbations in the hypothalamus-pituitary–testicular axis and declining serum testosterone concentrations. The major changes are...

"Age-related" testosterone deficiency, or age-related hypogonadism, is the term given when the underlying cause of testosterone deficiency is unknown. There is a debate about whether or not "age-related" testosterone deficiency should be treated. There is no evidence, however, that...

Dr. Abe Morgentaler has been working in his field for some 40 years now. In this video, he talks about what he's learned during the decades he has spent studying testosterone and how mainstream medicine has been slow to understand the importance of testosterone deficiency and the benefits of...

Testosterone recovery therapy targeting dysfunctional Leydig cells(2022) Samuel Garza and Vassilios Papadopoulos Abstract Reduced serum testosterone affects millions of men across the world and has been linked to several comorbidities, metabolic dysfunctions, and quality of life changes. The...

The medicalization of testosterone: reinventing the elixir of life (2022) Thiago Gagliano‑Jucá · Mauricio Alvarez · Shehzad Basaria Abstract The pursuit of longevity, which during the Renaissance era was limited to longing for miraculous ways of rejuvenation, such as bathing in the fountain...

Bone health in aging men (2022) Karel David · Nick Narinx · Leen Antonio · Pieter Evenepoel · Frank Claessens · Brigitte Decallonne · Dirk Vanderschueren Abstract Osteoporosis does not only affect postmenopausal women but also aging men. The burden of disease is projected to increase with...