aging

  1. madman

    Targeting the Skeletal Muscle to Improve the Health and Wellbeing of Older Adults

    Shalender Bhasin, MB, BS https://www.utmb.edu/scoa/pepper-center/news/2026/06/08/utmb-pepper-center-lecture-highlights-advances-in-targeting-skeletal-muscle-for-healthy-aging UTMB Pepper Center Lecture Highlights Advances in Targeting Skeletal Muscle for Healthy Aging Jun 8, 2026, 09:11 AM...
  2. madman

    Advancing Muscle Health Research: Dr. Stuart Phillips on Nutrition, Aging, and Exercise

  3. madman

    Predicting Circulating Testosterone Concentrations in Individual Men

    * We devised a formula to calculate predicted total testosterone concentrations, based on meta-analyses of individual participant data from 21,074 men, aged 17-99 years, from nine cohort studies in Australia, Europe and North America of community-dwelling men with testosterone measured using...
  4. madman

    Enhancing Muscle Quality: A Deep Dive into Mitochondrial Science, Part 1/2

    * Currier explains MitoPure’s mechanism—stimulating mitophagy to recycle dysfunctional mitochondria—and reviews evidence from multiple clinical trials. He reveals a Sports Medicine study in elite male distance runners showing reduced creatine kinase and lower perceived exertion, suggesting...
  5. madman

    Brad Currier discusses Urolithin A and Resistance Training Guidelines

    * In this episode, the conversation begins with Urolithin A and Mitopure, exploring what it is, what it does in the body, and why it has become an area of interest for mitochondrial health and muscle function. Brad explains the proposed mechanisms, the current human evidence, and what outcomes...
  6. madman

    NAD⁺ Boosters – New Insights into Their Differential Modes of Action in Humans

    Stefan Christen, Metabolomics Researcher at Nestlé Research in Lausanne, Switzerland, presents " NAD⁺ Boosters – New Insights into Their Differential Modes of Action in Humans" at Longevity World Forum 2026. Conclusion & Take-home message
  7. madman

    Creatine for Muscle, Bone, Brain & Longevity (Plus Caffeine, Dosing, and Safety)

    07:17 Top Supplements Today 08:23 NAD Hype vs Evidence In this episode of the Flex Diet Podcast, I sit down with creatine researcher Dr. Darren Candow from the University of Regina to break down what the research actually says about creatine for muscle, performance, and body...
  8. madman

    Should Men on TRT Get a Coronary Artery Calcium (CAC) Score?

    Curated By Nelson Vergel | ExcelMale.com | Updated May 2026 If you're on testosterone replacement therapy (TRT), you're likely paying close attention to your labs - testosterone levels, estradiol, hematocrit, and lipids. But one critical cardiovascular test remains underutilized by most men on...
  9. madman

    Mitochondria, Muscle, & Aging: What Longevity Drugs Miss

    Dr. Mark Tarnopolsky's VO2 max was once 87.6 ml/kg/min — an elite-level mark few humans have reached. He's competed at three world championships in three different sports. He's also had three cardiac ablation surgeries, bled from his bowels after races, and watched his vision tunnel to a speck...
  10. madman

    Normal Testosterone Isn’t Enough: How SHBG Hides Low Free T in Older Men

    Abstract INTRODUCTION AND OBJECTIVES: Total testosterone (TT) measurement is widely used to diagnose male hypogonadism (MH). However, TT may be normal despite androgen deficiency when sex hormone-binding globulin (SHBG) is elevated, a condition often associated with ageing and chronic...
  11. madman

    Untangle the hidden links between chronic inflammation, aging, HIV, and comorbidities

  12. madman

    Why Do We Age? Dr Bradley Elliott on Biomarkers, Muscle, and What Longevity Science Still Doesn’t Know

    Dr Bradley Elliott — physiologist, university lecturer, and a trustee and Communications Lead at the British Society for Research on Ageing — joins host Daphna for a refreshingly honest conversation about what longevity science actually knows and what we still cannot explain. This episode cuts...
  13. madman

    Creatine for Women's Health

  14. madman

    Why Protein Advice Is Wrong

    What if the official protein advice you’ve been following is made for you to survive and not to thrive? Skeletal muscle metabolism expert Prof. Stuart Phillips explains why protein intake guidelines are failing you. Stuart Phillips is a professor of Kinesiology at McMaster University and one of...
  15. madman

    Functional Hypogonadism Uncovered: The Truth About Modern Testosterone Therapy and Men’s Health

    * Male hypogonadism is etiologically heterogeneous, broadly classified as: primary (hypergonadotropic) hypogonadism due to testes failure (e.g. from genetic conditions, trauma or gonadotoxic insults); secondary (hypogonadotropic) hypogonadism due to hypothalamic-pituitary disorders (e.g. tumors...
  16. madman

    The Molecule Behind Energy, Recovery, and Aging (And How to Protect It)

    01:30:55 Is NR worth supplementing for healthy individuals? Many symptoms attributed to aging are also consistent with chronic inflammatory stress and impaired NAD metabolism. Dr. Charles Brenner explains the mechanisms, the human data, and what interventions actually move the needle. He...
  17. madman

    Protein after 40: what does the science actually say about muscle health and aging?

    ABOUT PROFESSOR LUC VAN LOON: Professor Luc van Loon is Professor of Physiology of Exercise at Maastricht University in the Netherlands. He is one of the world's leading researchers on muscle protein metabolism, with particular expertise in how nutrition and exercise affect muscle health across...
  18. madman

    Vaginal Rejuvenation: Myths, Realities, & Medical Insights

    Vaginal rejuvenation is often misunderstood, misrepresented, and overdue for honest conversations in medicine. In this crossover episode between BackTable Urology and BackTable OBGYN, Dr. Nirit Rosenblum, a urology and OBGYN professor at NYU Langone Medical Center, is joined by Dr. Karyn Eilber...
  19. madman

    How Much Protein Per Meal Actually Builds Muscle?

    In this episode of The Proof, I’m joined by Dr Luc van Loon, one of the world’s leading researchers in protein metabolism, muscle physiology, and ageing. We explore what actually happens to protein once you eat it, how muscle adapts to training and inactivity, and why so much of the public...
  20. madman

    Exercise & nutritional interventions Healthspan & Lifespan

    Exercise & Nutritional Interventions: The Only Proven Strategies to Extend Human Healthspan | Dr. Mark Tarnopolsky | BlueOakNx Symposium Dr. Mark Tarnopolsky delivers a clinically-grounded presentation drawing from 35 years treating mitochondrial disease patients, revealing critical insights...
  21. madman

    Vascular aging-driven erectile dysfunction

    Key point being stressed here! * Age-related ED is a manifestation of systemic vascular pathology * Key contributors to age-related ED include reduced nitric oxide (NO) bioavailability due to endothelial oxidative stress and inflammation, diminished cavernosal smooth muscle content leading...
  22. madman

    Creatine for Health and Performance

    Summary
  23. madman

    Muscle Health, Protein, and Longevity

    How much protein do we really need? And is resistance training more important than we thought? In this episode of The Ty Beal Show, Stuart Phillips, PhD, renowned expert in muscle health and aging at McMaster University, breaks down the science of muscle preservation across the lifespan. Stuart...
  24. madman

    A Day in the Life of a 102-Year-Old French Yogi

    For decades, Charlotte Chopin has been teaching yoga in Léré, a village in France. At 102 years old, she maintains a simple approach to aging well.
  25. madman

    Honoring Discovery and Dedication: Legends 2025 Celebrates Innovation at The Lundquist Institute

    https://lundquist.org/legends/ LEGENDS Each year, The Lundquist Institute honors outstanding researchers for their groundbreaking discoveries and commitment to finding solutions to the world’s most urgent medical problems. The Legends celebration event is a very special evening of renewing...
  26. madman

    Rewriting Aging: Dr. Mark Tarnopolsky on Mitochondria, Muscle & Longevity

    In this episode of The DNA of Things, Dr. Jeremy Koenig sits down with legendary physician-scientist Dr. Mark Tarnopolsky to explore how exercise, nutrition, and genetics intersect to reshape the aging process. With over 500 peer-reviewed publications and decades of research in neurometabolic...
  27. madman

    The New Standard in NAD-Boosting

    NAD-Boosting
  28. madman

    Strength Training & Protein After 50: How to Preserve Muscle, Boost Mobility, and Age Strong

    In this upcoming one-hour webinar with Dr. Stuart Phillips, Professor of Kinesiology and a leading researcher in the field, he will share how strength training and protein intake can help older adults maintain muscle, improve mobility, and support overall well-being. This session will offer...
  29. madman

    Muscle Aging is Not Inevitable: Professor Scott Trappe on Viral MRI Images, Fast-Twitch Fibres, and Staying Strong for Life

    Eye opener for many! Fast-twitch muscle fiber load/rep range training myth! 49:34-53:15 Guest Bio: Professor Scott Trappe is a renowned exercise physiologist at Ball State University's Human Performance Laboratory. His groundbreaking research on lifelong athletes, muscle fibre...
  30. D

    Impact of TRT and Supraphysiological Testosterone Doses on Biological Aging

    I've seen that some people measure their rate of aging using tools like genetic or epigenetic clocks (e.g., DNA methylation age). I'm wondering how different testosterone dosages, from standard TRT levels up to supraphysiological doses, might affect the speed of aging as measured by these...
  31. Fernando Almaguer

    Factors Involved in Immune Resilience and Longevity

    This guys channel is fascinating. N of 1 type experimentation with diet to see how blood markers correlate with increase or decrease of certain foods. He has great guests as well. This lecture explores immune resilience, a crucial factor for health and longevity that counteracts...
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