hypogonadism

  1. madman

    SUB-Q VS INTRAMUSCULAR TESTOSTERONE IN MALE HRT: PHARMACOKINETICS, SAFETY, TOLERABILITY, AND CLINICAL IMPLICATIONS

    * Esterification of testosterone increases its lipophilicity and enables its incorporation into oil-based vehicles to form a depot after injection. The duration of exposure depends not exclusively on the systemic half-life of free testosterone but also on release of the ester from the depot, its...
  2. C

    Functional hypogonadism after severe crisis, 17 kg weight loss & sleep issues – Reversible or permanent? (Looking for experiences)

    Hi everyone, Posting here to get some insights from others who might have been through a similar physiological crash. Context & Background: Demographics: 49-year-old male from Norway (where regulations for TRT/hormone replacement are extremely strict). I have done strength training my...
  3. madman

    Is Venous Thromboembolism a Real Risk in TRT?

    8th Annual Meeting of the Androgen Society 2026 presentations from the top experts in the field! Wayne JG Hellstrom * Definite need for large, long term, multicenter, prospective RCT in the general hypogonadal population to determine the true risks of increased Hct as a side effect of TRT...
  4. madman

    Dr. Morgentaler - Hematocrit and Testosterone

    00:00-9:35 https://www.excelmale.com/threads/understanding-testosterone-and-myth-busting-with-dr-abraham-morgentaler.34957/#post-315464 * While the precise mechanism underlying secondary polycythemia in the setting of TTh is still debated, it is likely that a longer duration of...
  5. madman

    T-Maxing, Low T, and the Truth: What Testosterone Really Does (and Doesn't Do)

    High hopes crushed LOL! That more T is better myth that needs to be put to rest! Those truly in the know would tell you that the majority of symptoms will be improved once you achieve a healthy FT which for most would be aiming for a healthy/high-end trough FT as in the upper 1/3rd! Listen...
  6. madman

    Hims Expands Testosterone Care with Injectable and Oral TRT, Its Largest Men’s Health Launch to Date

    https://investors.hims.com/news/news-details/2026/Hims-Expands-Testosterone-Care-with-Injectable-and-Oral-TRT-Its-Largest-Mens-Health-Launch-to-Date/default.aspx Starting today, Hims is closing that gap, providing eligible customers access to three new treatment options, including: Two...
  7. madman

    Testosterone and Calcified Plaque Volume

    8th Annual Meeting of the Androgen Society 2026 presentations from the top experts in the field! Matthew Budoff Manopause?! https://www.excelmale.com/threads/testosterone-and-cardiovascular-risk-the-traverse-trial-and-results-from-the-new-fda-label-change.32221/...
  8. madman

    The Role of Dihydrotestosterone (DHT) in Andrology

    8th Annual Meeting of the Androgen Society 2026 presentations from the top experts in the field! Dr. Michael Zitzmann Target organs of testosterone and its metabolites The Bifurcation of Testosterone: Amplification vs Aromatization The 5a-Reductase Distribution Map...
  9. madman

    Testosterone Deficiency: Androgen Society Consensus Guidance for Primary Care Management (2026)

    General Practitioner Consensus Update Why a GP Consensus Project? Goal Participants/authors The Process 2-Day Consensus Meeting
  10. madman

    Testosterone and Male Fertility - Part 1: Understanding the Risks

    In this episode, Dr. Tanginika Cuascud speaks with Dr. Thomas Masterson, urologist and male reproductive health specialist, about the factors influencing male fertility and the often-overlooked impact of testosterone treatment on sperm production. They discuss fertility trends, lifestyle...
  11. madman

    Testosterone Undecanoate Significantly Reduces LDL Cholesterol and Triglycerides in Men With Adult-Onset Testosterone Deficiency

    https://onlinelibrary.wiley.com/doi/10.1111/andr.70393 Table 1. Serum TT and lipids at baseline and final assessment in the total cohort stratified by TU and statin treatment. Table. 2 Lipid values at baseline and follow-up (24. 48, 72 and 96 months) in men with a follow-up duration...
  12. madman

    SWIMCLUB - Male Fertility + Performance Supplement

    https://swimclub.co/pages/about-us
  13. madman

    How Testosterone Changes Your Metabolism

    Testosterone influences far more than just libido and muscle growth: In this episode, Dr. Jonathan Apasu speaks with Prof. Farid Saad about the crucial role of testosterone in metabolism, insulin resistance, prediabetes, diabetes, and obesity. Together, they explain why testosterone deficiency...
  14. madman

    Can long-term testosterone therapy in men with class III obesity be an alternative to metabolic surgery?

    * Dr Saad says: “Long-term testosterone therapy in hypogonadal men resulted in profound and sustained in weight loss which may have contributed to reductions in mortality and cardiovascular events. Untreated men with hypogonadism gained weight.” * Dr Saad says: “Long-term testosterone therapy...
  15. madman

    How to Optimize Your Hormones: Testosterone, Sex Drive, & Aging

    Dr. Eisenberg is a board certified urologist and Professor of Urology at Stanford University. He also leads Stanford's Male Reproductive Medicine and Surgery Program. He specializes in men’s health, testosterone, fertility, and sexual dysfunction.He will also explain why reproductive health is...
  16. madman

    Lipocine Announces Health Canada Approval of TLANDO® for Testosterone Replacement Therapy

    Great new for Canadian as there will be 3 options now (Jatenzo, Kyzatrex and Tlando) for men interested in using the newer oral TU formulations! https://ir.lipocine.com/2026-10-07-Lipocine-Announces-Health-Canada-Approval-of-TLANDO-R-for-Testosterone-Replacement-Therapy SALT LAKE CITY, Oct...
  17. madman

    Experts review evidence on testosterone and prostate cancer

    https://www.urologytimes.com/view/experts-review-evidence-on-testosterone-and-prostate-cancer Abraham Morgentaler, MD, reviews evidence showing no association between testosterone therapy and prostate cancer risk and explains the saturation model of androgen action.
  18. madman

    Hegseth's Testosterone Plan: A Doctor Who Treats Veterans Responds

    19:43 What an 'optimal' testosterone level really is Dr. Mark Gordon * Optimal health is between the 50th and 75th percentile of the range The average man today is walking around with meaningfully less testosterone than his grandfather had at the same age — and the fix the military is...
  19. madman

    The Use of Human Chorionic Gonadotropin and Testosterone in Adolescents with Constitutional Delay of Growth and Puberty and Hypogonadism

    * This review integrates evidence across diagnostic, therapeutic, and psychosocial domains to clarify what is well supported, what remains provisional, and where the principal contradictions in the literature lie, and it proposes methodologically robust priorities for future research, including...
  20. madman

    The Sex Factor: How Sexual Health Fuels Longevity, Energy, and Well-Being

    https://www.penguinrandomhouse.com/books/804404/the-sex-factor-by-mohit-khera-md/ A leading sexual health physician introduces the groundbreaking concept that your sexual wellness may be the single most overlooked predictor of how well—and fully—you live, with a science-backed plan to maintain...
  21. madman

    Male Fertility: Evaluation and Optimization

    * Dr. Brannigan will explore what every man should know about fertility, including when to seek an evaluation, the role of semen analysis, hormonal testing, genetic factors, and common medical conditions that can impact sperm production and reproductive potential. Dr. Brannigan also discusses...
  22. madman

    Hypogonadism - Myths and Realities

    Learning Objectives HPG Axis Physiology Key TTh Takeaways https://www.adventhealth.com/institutes/research/team/john-tillet-md-1939
  23. madman

    ED Predicts Heart Attacks Better Than Chest Pain: The 2 Tests to Ask For

    Dr. Tobias Kohler * There T level at that point when they are healthy is a very important number. Most of the time it is going to be 500 or so, right? There are some published T levels per decade of life and it does go down. It's pretty rare to get above 1000 naturally considering that as a...
  24. madman

    Clinical Practice Guideline: Testosterone Deficiency in the Male Service Member

    https://www.dha.mil/HHPO The Department remains focused on building and maintaining a ready, lethal fighting force prepared to dominate the battlefield and achieve peace through strength. In his July 15, 2026, memorandum, "Health and Human Performance Optimization to Enhance Military...
  25. madman

    Weight loss and Testosterone Deficiency: T Therapy + GLP-1

    32:00-44:15 Case: 54-Year-Old Man with Vaculogenic ED Case Study: Body Composition Transformation THE EFFECTS OF COMBINED THERAPY ON HORMONAL AND METABOLIC PERFORMANCE DATA-DRIVEN INSIGHTS: QUANTITATIVE BIOMARKER CHANGES...
  26. madman

    Testosterone treatment for men who want to preserve fertility

    In this episode, Dr. Brandon & Dr. Morgentaler talk about testosterone treatment for men who want to preserve fertility, including Clomid, hCG, and enclomiphene. They also take a closer look at whether exercise actually increases testosterone, what the research shows about short-term changes...
  27. madman

    Getting to the Heart of Prostate Cancer: Identifying and Managing CV Risk in Patients Receiving ADT

    Educational Objectives In this activity, experts in prostate cancer discuss cardiovascular risk in patients receiving androgen-deprivation therapy (ADT). Upon completion of this activity, participants should be better able to: Evaluate the impacts of prostate cancer and ADT on...
  28. madman

    Erectile Dysfunction Myth Busting

    There’s a lot of misinformation online about erectile dysfunction, from miracle supplements to misconceptions about sexual performance and size. With so much conflicting information available, it can be difficult to know what’s true and what’s not. In this webinar, urologist and sexual health...
  29. madman

    Testosterone replacement therapy in Prostate cancer (Part 2)

    Dr. Samantha Strumeier * There's absolutely no evidence that testosterone replacement therapy causes prostate cancer, there's a lack of long-term data but I think you know we have a lot more data keeps coming out over the years and we should really hone in on that...
  30. madman

    In the Clinic - Managing Low Testosterone in Cancer (Part 1)

    Dr. Strumeier spent most of her career at MSK under the legendary Dr. Mulhall! https://simplyoncology.buzzsprout.com/2342317/episodes/19577727-episode-113-in-the-clinic-managing-low-testosterone-in-cancer-with-dr-samantha-strumeier Join us as we cover the effect of cancer and its treatment...
  31. madman

    Talking Sexual Health – Part 1: Creating Safe Spaces

    In this podcast episode, host Tanginika Cuascud speaks with urologist and sexual health specialist Amy Pearlman about creating more open and supportive conversations around sexual health. Amy shares her journey into urology and sexual medicine and discusses the importance of creating a safe...

hypogonadism

hypogonadism

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