hypogonadism

Curated By Nelson Vergel | ExcelMale.com | Updated May 2026 Most men assume their penis will stay exactly as they remember it from their 20s. Then, somewhere in their 40s or 50s, things start to feel different. The erections are not quite as firm, morning wood has become less reliable, and a...

Justin Dubin, M.D. Urologist Director of Men’s Sexual Health Baptist Health Miami Cancer Institute

15:01 - Diagnosis, Assessment and Evaluation Male factor infertility accounts for nearly half of all infertility cases, yet male evaluation is often delayed or overlooked. In this episode of BackTable Urology, Dr. Robert Brannigan joins guest host Dr. Catherine Nam to unpack the 2024...

https://www.urologytimes.com/view/fda-grants-clearance-to-total-testosterone-assay The FDA has granted clearance to Revvity’s automated chemiluminescence immunoassay (ChLIA) for total testosterone measurement.1 The assay is designed to support diagnostic testing for androgen-related disorders...

Listen closely Dr/ Khera hitting the nail on the head here! T is a threshold hormone! Set-points ya dig! 31:15- 35:34 * The risks of chasing supraphysiological levels Most people don’t take their health seriously until something goes wrong. In this conversation with Dr Mohit Khera, we...

Another one under the belt for Dr. Bhasin! https://edhub.ama-assn.org/jn-learning/audio-player/19061825 Interview with Shalender Bhasin, MBBS, author of Testosterone Treatment in Prostate Cancer Survivors With Hypogonadism: A Randomized Clinical Trial, and Peter C. Albertsen, MD, author...

https://jamanetwork.com/journals/jamainternalmedicine/article-abstract/2848537#google_vignette

No one should be using/elying on the known to be inaccurate direct immunoassay! Speakers: Jessica Colon-Franco, Ph.D., Cleveland Clinic; Leslie Farris, Ph.D., Cleveland Clinic Accurate assessment of free testosterone (FT) is essential in evaluating androgen...

https://mariuspharma.com/news/marius-pharmaceuticals-announces-key-leadership-expansion-and-launch-of-marius-ai-positioning-the-company-as-the-first-ai-native-pharmaceutical-company/ Raleigh, N.C., (May 7th, 2026) – Marius Pharmaceuticals, Inc., the makers of KYZATREX® (testosterone...

Shalin Shah explains how testosterone serves as a key biomarker for overall health and outlines common symptoms that indicate testing is needed: including fatigue, muscle loss, and decreased libido. He emphasizes that while lifestyle factors like diet, sleep, and exercise are foundational...

* The CDC’s Clinical Hormone Standardization Programs standardize the total testosterone assay so that results are accurate, comparable, and clinically meaningful wherever they are performed * By calibrating assays to a common reference method and enforcing stringent performance criteria, CDC...

Was bound to happen sooner or later! There was still some limited back stock floating around. I am sitting on numerous vials and have some Delatestryl left to boot. All we have know are slim pickings the two generics Hikma TE and Taro TC. Even then everyone is going to be stuck with the Taro...

Nothing ground breaking here as the majority of men will stick with the go to medium acting esterified TC/TE! Flexible dosing and easily titrated are key here let alone weekly injections whether once weekly or more frequently take the cake when it comes to taking advantage of the anabolic...

48-Position Custom Deep Well Plate For In Vitro Equilibrium Dialysis at a 1:1 Sample to Buffer Volume Ratio * CDC scientists have developed a new design for a multi-well dialysis microplate for equilibrium dialysis. The unique design accommodates a 1:1 buffer to sample ratio and provides...

Abstract INTRODUCTION AND OBJECTIVES: Clomiphene citrate has been used off-label to treat male hypogonadism by stimulating endogenous gonadotropin secretion. Enclomiphene, the trans-isomer of clomiphene, is increasingly prescribed, but comparative data remain limited. We aimed to assess whether...

Abstract INTRODUCTION AND OBJECTIVES: The relationship between testosterone replacement therapy (TRT) and obstructive sleep apnea (OSA) is an emerging field of interest. TRT is typically contraindicated in patients with severe uncontrolled OSA, but our previous research has shown OSA risk...

Abstract INTRODUCTION AND OBJECTIVES: Human chorionic gonadotropin (HCG) is commonly added to testosterone therapy (TTh) to preserve testicular function. In clinical experience, many men with testosterone deficiency express a preference for adjunctive HCG with TTh. We performed a...

Abstract INTRODUCTION AND OBJECTIVES: Clomiphene citrate (CC) is increasingly used off-label to treat male hypogonadism while preserving gonadal function. CC has been associated with dyslipidemia in women treated for ovulatory dysfunction, and preliminary data from our institution previously...

Abstract INTRODUCTION AND OBJECTIVES: Total testosterone (TT) measurement is widely used to diagnose male hypogonadism (MH). However, TT may be normal despite androgen deficiency when sex hormone-binding globulin (SHBG) is elevated, a condition often associated with ageing and chronic...

Abstract INTRODUCTION AND OBJECTIVES: To evaluate FSH recovery rates and sperm production in men with testosterone therapy (TTh)-induced azoospermia treated with hCG alone versus hCG combined with clomiphene citrate, focusing on men with severely suppressed baseline FSH. METHODS...

Abstract INTRODUCTION AND OBJECTIVES: The preferred treatment for hypogonadism, testosterone replacement therapy (TRT), has a varying efficacy that is currently not understood. This observation may be explained by polymorphism of the androgen receptor (AR), a ligand-binding transcription factor...

Abstract INTRODUCTION AND OBJECTIVES: Testosterone therapy (TTh) is known to suppress spermatogenesis, but combination TTh with human chorionic gonadotropin (hCG) has been shown to maintain spermatogenesis in a small 26-patient case series. That study did not account for prior fertility (or...

https://www.joinvoy.com/experts/dr-jeff-foster https://www.h3health.co.uk/ https://www.joinvoy.com/trt https://www.excelmale.com/threads/british-society-for-sexual-medicine-guidelines-on-male-adult-td.27188/...

* Despite these limitations, the findings of this review provide valuable guidance for clinical practice. The consistent benefit of combined hCG and FSH therapy in inducing spermatogenesis and achieving pregnancy supports its role as a first-line treatment for men with HH and infertility. Future...

* Panelists address the risk of polycythemia associated with testosterone therapy, particularly injectable formulations, and emphasize the importance of monitoring hematocrit changes relative to baseline values rather than absolute thresholds alone Moderated by Manoj Monga, MD, FACS...

https://www.urologyhealth.org/healthy-living/urology-care-podcast/sexual-health-podcasts/vasectomy-reversal-leads-to-couples-restored-fertility-with-dr-larry-lipshultz

https://academic.oup.com/jsm/article/23/3/qdaf392/8507270

https://www.nejm.org/doi/abs/10.1056/NEJMra2202438

Testosterone levels have dropped more than 25% over the past two decades — and the downstream effects on brain health, cardiovascular function, energy, and libido are only beginning to be understood. Leslie sits down with Shalin Shah, CEO of Marius Pharmaceuticals, to go deep on one of the most...