kyzatrex

  1. F

    Importance of meals on oral testosterone undecanoate

    Just checking for feedback for those that are on any of the oral TU. How important is what you eat with the medication for you? Have you had your labs checked while eating and dosed with healthy fat? I searched for this on here and it's not commonly discussed. My doctor and I have reverted back...
  2. madman

    What You Don't Know About Testosterone

    Shalin Shah explains how testosterone serves as a key biomarker for overall health and outlines common symptoms that indicate testing is needed: including fatigue, muscle loss, and decreased libido. He emphasizes that while lifestyle factors like diet, sleep, and exercise are foundational...
  3. V

    Sleeping much better on Kyzatrex vs injections

    I had been on daily subq injections of T cyp for 7 years. During the entire time, my sleep quality was pretty poor. It would take 30-60 minutes for me to fall asleep. I would wake 1-3 times each night to go to the bathroom (1 was a good night, 3 a bad night). I would average a good 3-4 hour...
  4. madman

    Shalin Shah of Marius Pharmaceuticals - Past, present, and future of testosterone therapy

    At the Clinical Application of Longevity Medicine 2026 conference, cardiologist and longevity physician Dr. Abid sits down with Shalin of Marius Pharmaceuticals — makers of Kyzatrex, the FDA-approved oral testosterone — for a candid conversation about the past, present, and future of...
  5. madman

    Unlocking the Truth About Testosterone: Myths, Science, & Innovations - The shift from injections to oral T solutions

    • The shift from injections to oral testosterone solutions In this episode, Luke sits down with Shalin Shah, CEO of Marius Pharmaceuticals, to unpack the truth about testosterone. They explore the science, debunk common myths, and discuss innovative solutions designed to make hormone...
  6. J

    Week three on Oral TRT: the warm / wired thing is fading, and meals matter more than I thought

    Quick update since my last post. i’m a few weeks in on kyzatrex now and the warm/restless episodes i mentioned are still happening sometimes, but they’re way less intense. early on it felt like these random little heat waves with a slightly wired feeling for like 20–30 mins, usually after a...
  7. J

    Week one on kyzatrex: the “convenience” part is real

    Quick update since i posted last week. i’m about a week into kyzatrex (oral tu) and honestly the biggest change so far isn’t some crazy boost… it’s just that i’m not thinking about needles at all. i travel a lot and not having to pack pins / deal with airport stuff already feels like a win. As...
  8. madman

    Oral Testosterone Therapy: Is It Really Safe?

    * newer generation of oral testosterone therapy is forcing the medical world to update outdated talking points What if everything you thought you knew about testosterone therapy was wrong? For decades, we’ve been told oral testosterone is dangerous—hard on the liver, risky for the heart...
  9. madman

    PART II - The 1st FDA approved oral testosterone: Meet Kyzatrex®

    * 22:35 Why Kyzatrex Is Cash-Pay * 07:10 Real-World Kyzatrex Results Founder, CEO, and visionary behind Marius Pharmaceuticals, the company that brought Kyzatrex to market—the first FDA-approved oral testosterone replacement therapy. With a background in private equity and investing, he...
  10. madman

    How Oral Testosterone Will REVOLUTIONIZE TRT

    Shalin Shah is the CEO of Marius Pharmaceuticals, where he leads the development of novel therapies for testosterone deficiency and metabolic health. His background spans finance, private equity, and pharmaceutical strategy, with a focus on patient-centered innovation and education around...
  11. Nelson Vergel

    Kyzatrex: The Complete Guide to Oral Testosterone Replacement Therapy

    Kyzatrex: The Complete Guide to Oral Testosterone Replacement Therapy Curated By Nelson Vergel | ExcelMale.com | Updated January 2026 Introduction What if you could restore your testosterone levels to normal without injections, messy gels, or painful pellet insertions? For millions of men...
  12. madman

    The 1st FDA approved oral Testosterone: Meet Kyzatrex®

    Founder, CEO, and visionary behind Marius Pharmaceuticals, the company that brought Kyzatrex to market—the first FDA-approved oral testosterone replacement therapy. With a background in private equity and investing, he moved into biotech to solve a long-standing problem in hormone health: making...
  13. B

    Does oral testosterone add to your existing natural levels or will it suppress natural levels?

    For example, if your current natural levels are at 400, and you take oral testosterone will the oral testosterone add to the level of your natural testosterone or could it possibly suppress your natural production and maybe make your levels actually lower depending on how well you absorb the...
  14. madman

    Pill vs. Needle: The science behind the new oral therapy replacing injections

    Men are living, on average, 7 years less than women. According to Shalin Shah, CEO of Marius Pharmaceuticals, the medical community has ignored a cause for decades due to stigma, "gym bro" stereotypes, and outdated science. In this episode, Daniel Robbins sits down with Shalin Shah to reveal...
  15. madman

    menMD - Kyzatrex® (testosterone undecanoate) twice-daily oral capsule

    * $179 per bottle (120 capsules) https://menmd.com/product/kyzatrex/
  16. Nelson Vergel

    Oral Testosterone Therapy: A Complete Guide to Jatenzo, Tlando, Kyzatrex, and Emerging Options

    By Nelson Vergel | ExcelMale.com | Updated December 2025 Summary: This comprehensive guide examines the development of FDA-approved oral testosterone products—Jatenzo, Tlando, and Kyzatrex—which overcome the liver toxicity problems of earlier oral formulations by using testosterone...
  17. A

    What are your thoughts on Enclomiphene with occasional Kyzatrex use?

    I heard Dr. Sun and Dr. Tatem say that they do it. They are on enclomiphene but do use kyzatrex in the afternoon occasionally for a boost. This is exactly what I am contemplating. I see the clomid/kyzatrex case study materials but am curious if anyone has experience with what I described the...
  18. A

    I tried searching but had no luck. Has anyone on this forum tried adding kyzatrex occasionally to their enclomiphene protocol?

    I heard Dr. Sun and Dr. Tatem say that they do it. They are on enclomiphene but do use kyzatrex in the afternoon occasionally for a boost. This is exactly what I am contemplating. I see the clomid/kyzatrex case study materials but am curious if anyone has experience with what I described the...
  19. B

    Kyzatrex vs Maximus Native T

    Is there any real difference between these 2 forms of oral testosterone? Do they have different half-life's? Does one seem more effective? I'm taking Maximus oral T at the moment 800 mg in the morning. I've been thinking about splitting the dose to 400 in the morning and 400 around lunch time...
  20. madman

    What are the Expected Changes in Free Testosterone and SHBG With KYZATREX®?

    ANDREW Y. SUN, MD UROLOGIST 2X Increase of Mean Free Testosterone 30% Reduction of Mean SHBG
  21. madman

    What is the Optimal Lab Timing for Patients Taking KYZATREX®?

    ANDREW Y. SUN, MD UROLOGIST Peak T level Tmax (≈3-5 hrs) post-dose administration
  22. madman

    What is the risk of liver toxicity with KYZATREX®

    ANDREW Y. SUN, MD, UROLOGIST
  23. madman

    KYZATREX® Safe for your liver: Lymphatic Absorption

    * The good news is that KYZATREX was specifically designed to be absorbed lymphatically. This means it bypasses your liver avoiding the liver toxicity associated with oral testosterone medications of the past. Kyzatrex® (testosterone undecanoate) an oral testosterone therapy Taken...
  24. F

    Kyzatrex Health Canada approval

    Has anyone seen any updates on Kyzatrex approval by Health Canada? All I can find is approval was expected by the end of 2025 Q2 and we are closing in on Q4
  25. madman

    FDA-Approved Oral Testosterone Therapy KYZATREX® Now on Hims & Hers: Marius Pharmaceuticals Expands Access for Men’s Health & HRT

    https://www.globenewswire.com/news-release/2025/09/10/3147991/0/en/marius-pharmaceuticals-and-hims-hers-collaborate-to-expand-access-to-kyzatrex-testosterone-undecanoate-ciii-capsules-the-first-fda-approved-oral-testosterone-therapy-offered-on-the.html RALEIGH, N.C., Sept. 10, 2025 (GLOBE...
  26. madman

    Oral Testosterone For Better Health

    Dr. Sun has treated over 1000 men with oral TU! Most men do better 300-400 mg BID. His breakfast/lunch dosing protocol is the most popular! Curious about the real power of testosterone beyond the realm of bodybuilding? Join us as we sit down with Dr Andrew Sun, a fellowship-trained...
  27. Nelson Vergel

    The Evolution of Testosterone Products in the U.S. (1935-2025)

    Thanks to Dr Sun for this diagram. Timeline details (left → right) YearProduct (image above/below the line)Form & delivery 1935-1937No product image—text block below the line: “Testosterone first synthesized” with a bullet list of early preparations (oral 17α-methyltestosterone, injectable...
  28. madman

    Oral T : KYZATREX the Next Frontier of Testosterone Replacement Therapy

    * we dive deep into the myths around oral testosterone, why SHBG levels matter, how testosterone therapy affects inflammation, cardiovascular risk, cognition, libido, and longevity, and why optimizing free testosterone—not just total T—is the true goal. In this episode, I’m joined by...
  29. madman

    KYZATREX® (TU) - Should Oral Testosterone Be Your First Line Therapy?

    In this KYZATREX webinar, Dr. Andrew Sun explores the evolution of testosterone therapy and the growing role of oral options. He reviews clinical data on KYZATREX, discusses treatment considerations, and shares practical tips for managing patient expectations when starting oral testosterone...
  30. madman

    Shifting the Testosterone Treatment Paradigm with Oral Testosterone (Kyzatrex)

    Again you heard it here first! Nelson's domain the one and only! Very informative webinar on the use of the newer oral TU formulations. Testosterone therapy has long been dominated by injectable and topical formulations, but the landscape is evolving. This webinar explores how oral...
Back
Top