prolactin

  1. W

    Crushed Prolactin levels with Cabergoline

    How long does it take for prolactin levels to naturally rise back up after you accidentally crushed it with Cabergoline? I did this recently and I’m having trouble getting erections for the first time ever. Hoping it will recover soon.
  2. T

    Is there any benefit to crushing prolactin down to nothing?

    Does anyone have experience with crushing their prolactin levels down to almost nothing? My prolactin levels have always sat mid range and as I get older I’ve noticed my refractory period isn’t quite as great as it used to be. It’s got me curious about prolactin and whether I should try...
  3. G

    Dr. ordered MRI to check for prolactinoma

    For the last 4 years my Prolactin has been slightly elevated (above the high range) on every test. I had a Macroprolactin test and confirmed it is high prolactin. My Doc has ordered a MRI. I also should mention that I have low Estrogen, I have never taken an AI, been on TRT for 12 years. I take...
  4. madman

    Clinical Impact of New Reference Intervals for the Roche Prolactin II Immunoassay

    * The new upper limit for the Roche assay was 37.8 ng/mL (females) and 22.8 ng/mL (males). The manufacturer-defined limits were 23.3 ng/mL and 15.2 ng/mL, respectively. New intervals for the Siemens assay matched the manufacturer. No cases of clinically significant pathophysiologic prolactin...
  5. madman

    THE METABOLIC ROLE OF PROLACTIN: A SYSTEMATIC REVIEW AND META-ANALYSIS

    Objectives Hyperprolactinemia has been proven to induce hypogonadism and metabolic derangements in both genders ,while the consequences of prolactin (PRL) deficiency have been poorly investigated. The aim of the study is to systematically review and analyze data from clinical studies focusing...
  6. madman

    The impact of hyperprolactinemia on sexual function

    https://academic.oup.com/jsm/article-abstract/21/3/197/7614825?redirectedFrom=fulltext Introduction Hyperprolactinemia, defined by elevated levels of prolactin,has a significant negative impact on sexual function through effects such as reduced sexual desire in men and women and erectile...
  7. G

    Seeking help with investigating symptoms. Zero sex drive, ED, High Prolactin, Low F.S.H, High Estrogen,

    Hello all I would really appreciate if anyone could provide some advice or point me in the right direction as to what could be going on. I have not managed to get anywhere with the health professionals where I live in the UK, so I thought to seek advice on here since their is plenty of people...
  8. madman

    Prolactinomas Resistant to Dopamine Agonists

    Abstract Prolactinomas are the most common functional pituitary tumors, accounting for 40% of all pituitary adenomas. Medical treatment with dopamine agonists (DA), mainly cabergoline, is considered the primary therapy for these patients. Prolactin normalization is achieved in 80-90% of...
  9. S

    Pramipexole instead of Cabergoline

    I've been using cabergoline with some success as my prolactin is always high normal and not optimal. It works well, and allow me to cum quicker, and in a some cases multiple times. However I'm very risk adverse and don't like the effects caber can have on the heart value, so I wanted to give...
  10. Marchickney

    Dostinex - Cabergoline - Cardiac Risks

    Hi, Was researching Dostinex/Cabergoline as was considering it might be worth trying libido/refractory period wise and though I best check potential sides......Mmmm glad i did ! I would not recommend anyone takes this drug.......... According to the British National Institute for Health & care...
  11. Z

    Feel worse with higher test levels

    I’m seeing a lot more post with people who have test levels above 1000 who feel crappy. Even with everything else in range e2, DHT, prolactin etc. I’ve also have seen post of people almost using microdose amounts and feeling way better. My question is, is this the new thing? Because my doctor...
  12. madman

    The metabolic role of prolactin

    The metabolic role of prolactin: systematic review, meta-analysis and preclinical considerations (2022) Giovanni Corona, Giulia Rastrelli, Paolo Comeglio, Federica Guaraldi, Diego Mazzatena, Alessandra Sforza , Linda Vignozzib and Mario Maggi ABSTRACT Introduction: Hyperprolactinemia has...
  13. K

    When is Prolactin too high and what are benefits of lowering it

    My Prolactin is a bit high at 448 and the UK range is 86-324 mU/L. One doc said to me its not a problem another said I should take Cabergoline to lower it at 0.25mg twice a week. I wondered what is the benefit to lowering it to what level for us on TRT. I was told its normal to have high...
  14. madman

    Surgery as a first-line option for prolactinomas

    Surgery as a first-line option for prolactinomas (2022) Adam Mamelak ABSTRACT Introduction: Treatment of prolactinomas with dopamine agonists has been the established first-line treatment option for many years, with surgery reserved for refractory cases or medication intolerance. This...
  15. madman

    Male Sex Hormones

    Male Sex Hormones in Andrology Today (2022) Nicola Bianchi, Olga Prontera, Mauro Dicuio, Sergio Concetti, Alessandra Sforza, and Giovanni Corona 19.1 Introduction Male sexual function is the result of the communication among organic relational and intrapsychic components, which mutually...
  16. F

    For Those That Get Headaches on TRT

    There are a few threads on headaches, but I thought I’d start one dedicated for anyone who wants to solicit or provide advice and feedback on headaches. If you previously had or currently still experience headaches, please share your thoughts here. I am prone to headaches and have been my whole...
  17. T

    Big Prolactin Increase

    I don't have all of the results from my 6-week labs back yet, but I did get my Prolactin back. It shot up from a 7 ng/mL before starting TRT to 18.8 ng/mL. I definitely noticed side effects from that as it has taken much longer for me to reach orgasm. I didn't have sex for 48 hours prior to...
  18. J

    What causes low prolactin and IGF-1 when all else looks great?

    I received my new labs after 8 weeks on my new protocol. I don't take T. I take HCG 250IU x4wk and 50mg enclomiphene x 4wk. TT is 956 ng/dL r264-916, FT 17.3 pg/dL r6.6-18.1, E 38.4 pg/dL r7.6-42.6, but prolactin is 3.6 ng/dL r4.0-15.2, and IGF-1 65 ng/mL r64-240. I'm concerned about the...
  19. R

    On TRT and low lobido

    Hi Guys, I’ve been on TRT for a while now and take the following meds regularly. Current meds I’m on: Test Cyp - 0.3ml x 2 times a week 200 mg/ml (so thats 60mg twice a week) Anastrozole - 0.5mg x 2 times a week I’ve noticed that I have been lacking in sexual desire most of the time. I can...
  20. S

    Clomid for 1.5 years - recent changes, prolactin?

    Hi All, So basically I am on Clomiphene treatment to boost my testosterone (before I started 1.5 years ago my Testosterone was 11.5 and my LH 3.0 and oestradiol 156). I have sent the below to my private specialist. Could the rise in prolactin explain why my Testosterone went down so much since...
  21. D

    Effects of zinc on prolactin

    "Zinc-treated patients had significantly lower serum prolactin levels (11 +/- 4 ng/ml v 29 +/- 7 ng/ml) than untreated patients." https://pubmed.ncbi.nlm.nih.gov/2864486/
  22. D

    New bloods in, very high prolactin and somewhat high e2. Would a small dose ai help? Or should I look to cabergoline

    High prolactin, e2 somewhat high, would an ai help? Or should I look into caber. On 100mg test E split everyday injections and added calcium d glucarate for e2 and P5P for prolactin, since starting P5P prolactin has increased from 19-27.8. Also looking to maybe increase T dose to get it into the...
  23. T

    Low Prolactin

    Hi.... Does anyone know of a known way to raise prolactin levels in a male? Mine is very low and I was curious if anyone knows of a way I can experiment raising a bit.
  24. Z

    Prolactin crashed

    Hello, I recently started taking cabergoline to help my RLS. I am on hormone therapy. The last few weeks I have noticed I felt pretty crappy. So I got my levels check and one thing I noticed was my my prolactin was undectable. Was wondering if I stop the cabergoline how long it will take for my...
  25. G

    Progesterone’s effect on prolactin

    Does exogenous progesterone lower prolactin levels?
  26. M

    Healthy Prolactin level

    I have finally decided to check on my prolactin, test below taken one hour before my weekly injection. 330 reference Range (86-324) considering I am a bit on the high side I believe after my injection I will go higher right ? should I try to lower prolactin a bit ?
  27. G

    Bloodwork comparison after 10 weeks of TRT

    Hello, friends. This is my first post here. I really appreciate there is a forum to talk about it, so I thank you all in advance. So, I started TRT 10 weeks ago. This is my pre-TRT and 10-week in bloodwork. Most recent on the right side. My protocol is 120mg/wk test cyp along with 250ui EOD of...
  28. O

    Prolactin 3.6 NG/ml. Causing sexual dysfunction? Caused by Curcumin?

    Hello all, I've been having very weak orgasms, low semen volume, very low penis sensitivity for around two years, maybe longer. I am NOT on TRT. My Prolactin came back at 3.6 ng/ml with a reference range of 2.0-18.0. Could this cause an issue? Is this low? Also, I just read that Curcumin...
  29. P

    Cypionate + HCG - zero libido :(

    Hi All! My first post - I hope you can help me! I am on 0.2ml Cypionate (200mg/ml - so 40mg) and 250IU HCG 3 times a week (Mon/Wed/Fri). Sub Cutaneous for both. I sleep well and don't feel fatigue in the daytime (unlike before TRT). I am tapering off Mirtazapine - down to 7.5mg from 30mg 2...
  30. R

    Perplexing result.. thoughts?

    Hi there, I'd really appreciate any thoughts or guidance on protocol/results below. I am quite surprised by the prolactin result, and even the T and E result as I am on a low daily dose and this is before my next injection. Any thoughts would be very appreciated. Purpose is TRT and not sport...
  31. R

    Prolactin level

    I am on opioid pain medication, I think that is why my prolactin is out of range little elevated. How can I reduce it, with vitamin or other way? Mine sometimes from 22 to 49. Never comes in normal range which is 2 to 18 nanograms per milliliter (ng/mL) Is it safe to use cabergoline for a...
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