Trimix

Trimix is a compounded injectable medication containing alprostadil, papaverine, and phentolamine, used to produce reliable erections when PDE5 inhibitors like Cialis or Viagra stop working. It is injected into the side of the penis using an insulin syringe, typically producing an erection within 5 to 15 minutes that lasts 30 to 90 minutes depending on dose. Threads in this tag cover starting doses, titration, injection technique, side effects such as priapism and scar tissue, sourcing from compounding pharmacies, and how men integrate Trimix with TRT protocols.
  1. J

    My Journey to Severe ED and Trimix

    I am currently 56. This thread is about my journey with ED, which started at 40. And got progressively worse. I have good lipids, no risk factors for CVD, excellent insulin resistance, am fit and very low body fat and muscly physique. Yes : my ED has confounded doctors but then, none of them...
  2. Z

    New protocol

    So after going over labs today with my doctor. (Not going to post them, just because essentially from all the research I have done on this forum and others things seemed pretty normal.) I will just post the basics real quick tbiugh TT-917 E2 (ultra sensitive)-17 SHGB- 26 Prolactin- I can’t...
  3. W

    Using Expired Trimix and Mixture Strength Question

    I'm a first time Trimix user and I ordered some trimix from Defy medical that's been sitting on the floor of my apartment for a few months. Frankly, I've been working up the courage to inject my dick. The package says "discard after 10/31/2018" but I don't know if that still applies if you...
  4. njpbronk

    More Disappointments With Trimix

    But I’m not giving up yet. 1. I’m up to a .270 ml injection and I’m only about 50% erect. 2. It doesn’t seem to be working as well as it did the first few times 3. I’ve gotten a bruise 3 times. 4. A lump 1 time 5. Didn’t work 3 times 6. Resistance when injecting 1 time
  5. njpbronk

    TRIMIX, Day after soreness & Location

    Three weeks into using Trimix. I’m still dialing in amount. Even on low volume injections my shaft is slightly sore the next day. Is this common? I’ve had 1 injection that didn’t work and I’m attributing that to I missed. Does an injection closer to base work better then mid shaft or...
  6. S

    Trimix question (new user)

    Just received my first shipment of Trimix. Directions on the package say .05 to .2 ML (5 to 20 units). When I spoke to my doctor he was kinda wishy washy about dosage. He said "eh... you might want to try 3 or 4 units, maybe 5..." So I'm looking to hear from someone with experience who might...
  7. S

    Updated Trimix discussion - need advice on injecting

    I would like to start a new trimix thread for those of us who are new to the product. After considerable study (basically reading every thread on excel male going back years) I decided to take the plunge but I am doing so in a conservative and thoughtful way. I was torn between differing...
  8. S

    Some yet to be asked questions about Trimix

    I think I can safely be described as a TRT success story. I am 49 next month and went on TRT after being diagnosed with two massive varicoceles that required surgery. The effect TRT has had on my body composition and overall health have been amazing: body fat percentage dropped from 20% to...
  9. W

    Trimix - On the fence about starting

    I currently have a prescription for Trimix from Defy Medical, and the only thing keeping me from immediately filling it is the fear that I will develop a dependency on Trimix to get a boner if I start using it. My ED is usually only a big problem the first 1 to 2 times I'm with a girl. I think...
  10. Nelson Vergel

    Erectile Dysfunction 101 – Facts, Causes, and Management Options

    Erectile dysfunction (also known more commonly as impotence or sexual dysfunction) is the inability to maintain a sufficiently rigid erection for a satisfying sexual experience. According to the Global Survey of Sexual Attitudes and Behaviors, erectile dysfunction affects approximately 5-28% of...
  11. T

    Trimix for ED

    Currently taking trimix 10mcg/30mg/1mcg dose is about .05 cc and after taking it for a while now I still teeter on the 4 hr erection mark. Eventually will subside at about 3 hours and 45 mins with sudafed (not the extended release tablets) but I worry about priapism. Should I take less? If so...
  12. G

    CAVERJECT Effective Dosage

    Dear all....I am affected by a very tricky form of psychogenic ED...this means that "pills" sometimes work sometimes do not. As a result, the quality of my sex life is sub-optimal to say the least. I would like to try Trimix. In this regard I have already had an initial contact with Defy, and...
  13. B

    Trimix - Sharing what my Dr said about Sudafed (Phenylephrine)

    In doing my research on trimix I've come across several comments on Sudafed...thought I would share what my doctor advised me when he did my trial run with Trimix. Have some 30mg Sudafed (Phenylephrine) on hand. They keep it behind the counter, ask. if your erection is still standing...
  14. B

    Trimix newbie...thought I'd share initial impression

    Hello All, I'm new to the forum and as of today a new trimix user. The experience at the doctors office was not as horrible as I expected it to be, lol. He drew 30 units (0.30 ml) and injected 15 to start...didn't hurt at all. He checked on me after 15 minutes and I was about 50% erect so he...
  15. Nelson Vergel

    How to prevent prolonged erections (Priapism) caused by trimix

    HOW TO PREVENT PRIAPISM CAUSED BY TRIMIX What is priapism: Priapism is an erection which lasts more than 4 hours and is unrelieved by ejaculation. This condition is a true urological emergency and early treatment allows the best chance for functional recovery. Failure to manage this issue can...
  16. C

    TRT and cialis not quite cutting it

    Hey everyone, I started on TRT (T. Cyp and HCG and DHEA with Defy) in November 2016 and I feel so much better physically and emotionally. I’m 41, and my T has gone up from 200-300 before TRT to 655 (2-2017)! Although I am very thankful for the improvement, things in the sex department aren’t...
  17. R

    TRIMIX Forum

    So I've tried Trimix 5 times with varied results. This is the standard 30-10-1 mix from Empower. Attempt 1: 5 units (.05ml) decent erection lasting around a half hour. Attempt 2: 8 units (.08ml) resulting in an ER trip and an erection around 8 hours. 120mg Sudafed did nothing. Urologist in ER...
  18. Nelson Vergel

    Article: ExcelMale Testosterone FactSheets for Download

    ExcelMale FactSheets for Download Here are a few PDF files members can download to show to doctors or for own reference. I will be adding others. https://www.excelmale.com/register/
  19. Nelson Vergel

    Trimix Antidote-Treatment for Priaprism: PHENYLEPHRINE HCL INJECTION

    Priapism is a medical condition in which the erect penis does not return to its flaccid state, despite the absence of both physical and psychological stimulation, within four hours. Improper dosing of Trimix can cause priapism. Phenylephrine injections can be an antidote to an erection that...
  20. C

    Compounding Pharmacy FDA inspections

    I am considering going down the TRT and Trimix road, but I am concerned about compounding pharmacies and the safety of the products. I like researching things...so I found this: http://www.fda.gov/Drugs/GuidanceComplianceRegulatoryInformation/PharmacyCompounding/ucm339771.htm And also this...
  21. C

    Any doctors willing to prescribe trimix in Washington DC Metro area (Maryland, Virginia, DC)

    I was wondering if anyone had a good recommendation for a urologist or endo who would prescribe Trimix and TRT in the DC Metro area. I have had ED for 2 years and diagnosed with low-t 6 months ago. I will soon be starting TRT but have gone to two urologists and both have been dead set...
  22. C

    About to start TRT...incompetent docs?

    I am 41 and have had low-t for probably 2 years now, but only had it checked 6 months ago (total t = 308). -First Urologist, said exercise and lose weight for 3-6 months, and then try TRT. -Endocrinologist said Androgel and come back in 3 months. -Second Urologist (second opinion) said...
  23. C

    Trimix - QuadMix Fail

    I've been trying to get trimix dialed in for quite awhile now. First I was put on trimix, then after getting up to around 25 or 30 units they provided me a stronger solution of trimix. That didn't really do the trick either, so I'm now on my first vile of quad mix. That hasn't worked too well...
  24. T

    Trimix advice, soft glans, allergy meds

    Took first .05 dose of trimix. Worked for 2.5 hours, then I did some things to get it down. (Squats worked) so I will reduce the dose. I noticed that the glans was not as hard as when I get erect naturally. Reason? Was alone, maybe needed partner to be in the mood? Of course I was nervous...
  25. L

    Trimix injection

    Does someone here has a lead on where to get Trimix abroad ( Thailand) where I am working now? Thank you:o
  26. K

    what size needle for trimix?

    I got a Rx for Trimix today and I believe the needle is 30g - 1/2 inch. I thought about it afterwards, isn't a 1/2 needle too long? I don't want to inject it into my urethra. ;) she must think I'm "girthy".
  27. V

    How long does Trimix work once injected...

    As we users know, trimix doesn't make Mr. Johnson hard, there needs to be some stimulation to get things moving... What Im wondering is... If I injected, then went out to dinner, would Trimix still be hanging around waiting to help out, say an hour later... That would allow more spontaneity and...
  28. Nelson Vergel

    Interview with Compounding Product Expert Shaun Noorian from Empower Pharmacy

    Nelson Vergel: I'm very happy to have Shaun Noorian, the owner and manager of Empower Pharmacy in Houston. He's a member of ExcelMale.com, and answers a lot of questions there. He's also a member of our XXXXXXXX group called Testosterone Replacement Therapy Discussion and I consider him an...
  29. Nelson Vergel

    Interview with Expert Shaun Noorian from Empower Pharmacy- Part 1

    Nelson Vergel: I'm very happy to have Shaun Noorian, the owner and manager of Empower Rx Pharmacy in Houston. He's a member of ExcelMale.com, and answers a lot of questions there. He’s also a member of our XXXXXXXX group called Testosterone Replacement Therapy Discussion and I...
  30. P

    Has anyone had erections lasting more than 3 hours with Trimix?

    I am looking for best ways to prevent priaprism. I do not want to end up in an emergency room
  31. B

    HRT is changing my life

    I'm a 66 year old male that was having depression outbreaks quite frequently. Also, ED problems and was not able to have sex with my wife for the last 3 years, just could not get auseable erection. About 5 months ago found a sports medicine doctor who checked my T and it was in the "normal"...
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Trimix

Trimix Trimix is a compounded injectable medication containing alprostadil, papaverine, and phentolamine, used to produce reliable erections when PDE5 inhibitors like Cialis or Viagra stop working. It is injected into the side of the penis using an insulin syringe, typically producing an erection within 5 to 15 minutes that lasts 30 to 90 minutes depending on dose. Threads in this tag cover starting doses, titration, injection technique, side effects such as priapism and scar tissue, sourcing from compounding pharmacies, and how men integrate Trimix with TRT protocols.

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