I run labs about 90 minutes post topical, I try to get my numbers from the maximums instead of in a trough, partly because as I alluded I aromatase a lot and am sensitive to Estrogens, I try to manage that specifically as a peak value.
Too, I did a complicated days long set of labs in the past that showed me with exceptionally high numbers at ~90 minutes post cream (50mg/mL/2 clicks), but I was approaching sub 600 TT at ~4hours post application. At roughyl 8hrs post application I was in a Low T state.
I use my cream 4x (FOUR) times per day. I have low SHBG around 12-15 and metabolize very quickly, proven in those labs. Once per day was never going to work for me but that's the journey...what works for you.
Too, I did a complicated days long set of labs in the past that showed me with exceptionally high numbers at ~90 minutes post cream (50mg/mL/2 clicks), but I was approaching sub 600 TT at ~4hours post application. At roughyl 8hrs post application I was in a Low T state.
I use my cream 4x (FOUR) times per day. I have low SHBG around 12-15 and metabolize very quickly, proven in those labs. Once per day was never going to work for me but that's the journey...what works for you.