dht

* Androgens contribute to acne through increased sebum production, abnormal desquamation/comedone formation, and inflammation. https://www.hmpgloballearningnetwork.com/site/thederm/videos/hormonal-therapy-acne-dht-spironolactone-and-clascoterone Dr Lawrence Green discusses how androgens...

* After one year, most men showed an increase in the number of hairs and thicker hairs, especially in the front and temple areas. Many patients reported being more satisfied. The treat- ment was well tolerated. Only a small number had mild, temporary scalp redness or itching. No sexual or...

Does anyone have experience with crushing their prolactin levels down to almost nothing? My prolactin levels have always sat mid range and as I get older I’ve noticed my refractory period isn’t quite as great as it used to be. It’s got me curious about prolactin and whether I should try...

Key points here! * Genetic variants, including polymorphisms in the androgen receptor (AR) gene, influence individual susceptibility and therapeutic response. Highlights * Androgenetic alopecia (AGA) is the most common form of hair loss, affecting both men and women through a progressive...

30 years old, been on TRT for a year. Looking for similar experiences. Before starting TRT, my free T levels were around 0.150 nmol/L, I was clearly deficient. Labs: Total T: 20.78 nmol/L Free T: ~0.641 nmol/L SHBG: 10 nmol/L (below range) Estradiol: 63 pmol/L DHT: never tested LH/FSH...

Hoping a few of you can share your insight here, in particular those who have experience with exogenous DHT. In your experience, what has been your most optimal T/DHT ratio for erections and libido? I’m on 150mg/week Test E (split MWF), and have been experimenting with using DHT gel to alter...

I havent been able to dial in with injections. Ive tried both cyp and E, did subq EOD for longest time, then tried daily subq, daily IM, and last resort was 2x a wk IM which im currently almost 4 weeks into. Going to wait 6 weeks and pull labs but its not looking like this protocol is gonna help...

The 20 Most Influential Hair Research Studies of 2025 A Comprehensive Review of the Year's Groundbreaking Findings in Hair Loss Treatment and Research Based on Dr. Donovan's Year-End Webinar | December 29, 2025 As we close out 2025, it's an opportune time to reflect on the remarkable advances...

* These findings represent a significant advance in a condition that affects 1.2 to 2 billion men worldwide and is recognized for its emotional and social impact. Studies show that clascoterone 5% topical solution is completely new therapeutic approach to treating AGA. In blocking...

A Cellular Anatomy of Human BPH: Will it change clinical practice? By Douglas Strand, PhD Associate Professor and Vice Chair of Urology, UT Southwestern Medical Center

Hey guys, I’ve noticed a lot of people say they feel great when they change their protocol — new ester, new dose, new timing — but after things stabilize, they start feeling kind of “meh.” That made me wonder: does anyone here intentionally vary their dose a bit, based on how they feel? Like...

https://pmc.ncbi.nlm.nih.gov/articles/PMC23979/ "The enzymatic efficiency of the conversion of DHT to androstanediol increased 163-fold when the enzyme was incubated with fluoxetine and 63-fold with paroxetine but did not change substantially with imipramine. " Couldn't find follow-up...

I’ve been running daily 20 mg Testosterone Propionate (IM) along with 150 IU HCG (IM) every day. At first, I was getting a lot of energy — even a bit of anxiety sometimes — but lately that energy seems to have faded. I’m not sure if there’s some kind of downregulation happening or if something...

Hello, I got 10% DHT cream in lipsomal base 50ml. How much of cream do I use per day? There is no instructions or dosing. Im using it for the purpose of PFS. Im on TRT cream as well. Thanks

Hello all. Im dealing with PFS symptoms from the use of finasteride. I went on TRT cream for symptom relief, but did not get much DHT related symptom relief. Looking to add DHT gel to my protocol. Anybody experienced benefits in regards to PFS symptoms with the use of DHT gel? Please advise...

I’ve recently started to see injectable androsterone on the market. Out of curiousity, would it suppress your natural testosterone levels if taken alone?

It seems that the time for easily obtainable raw DHT powder is over, at least for Americans. There are a few DHT creams/gels with varying reputations, AlphaGels seeminglybeing the most well received. One source for pharmaceutical Andractim 2.5% DHT cream can be found on Vigorous Steve's source...

In this episode, Dr. Kevin Chu and Dr. Justin Dubin interview Dr. Rahul Mehan to discuss the importance of prostate health, particularly as men age. They explore the concept of 'prostate puberty' and the common symptoms of an enlarged prostate. The conversation shifts to the role of supplements...

Can't seem to really find a general consensus anywhere. Some people say DHT is important for a number of things and some say it isn't that critical after you finish developing. I started finasteride a couple of months ago, but I do not want this to be a discussion about the drug itself and its...

Dr. Lawrence J Green from Skinalliance LDB discusses if androgen hormones cause hair loss and acne. Learn more about the effects of testosterone and creatine on your skin health. In this informative video, Dr. Lawrence J. Green delves into the relationship between androgen hormones and common...

So I had my dht tested and it came back triple the range. This is just from 14mg Test E daily (I also inject .1mcg estradiol EOD because of low e2). Any thing to look at why I convert so much to DHT, I’m almost certain this is what lowers my E2 and gives me sides. Any natural ways to lower it? I...

Could someone help discern how to measure andractim. I have the standard name brand gel. My doc advised to take 4 clicks a day of a compounded cream at 125mg/ml. The pharmacy then decided that they cant/wont make it. So I got the andractim. I need help figuring out how to measure...

Hair loss is one of those things that can feel so isolating, especially for women. But trust me, you’re not alone, and it’s not your fault. I had an amazing conversation with Dr. Omer Ibrahim, a dermatologist who’s just as passionate as I am about breaking down the stigma and getting real...

It’s not quite as off-the-wall as it sounds. We know that as serum testosterone increases the 5α-reductase enzyme starts to saturate, leading to a reduced efficiency in DHT creation, illustrated thusly: Even so, with high testosterone a lack of DHT is not going to be a problem; there’s still...

For men out there like myself who struggle with easily crashing their E2 on an AI (even with microdoses), yet still experience high E2 symptoms (itchy, sensitive nips, bloating etc) can topical DHT be used to replace an AI? I’ve found that using topical DHT eliminates any E2 sides that...

Say what you like, but I want higher DHT! Deeper voice, manly chest hair, higher libido, and fortunately I am not prone to male-pattern baldness. What testosterone formulations help increase DHT? Is scrotal cream/gel/patch the only way? What else can help increase DHT? And perhaps more...

I've been on TRT for roughly 3.5 years now, with very limited results. I started and kept using Test E most of this time. In the honeymoon phase I had great symptom relief, however after 3 months almost all of those symptoms returned, I only felt better emotionally and mentally. Honestly I was...

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220510/ https://pubmed.ncbi.nlm.nih.gov/6249575/

As we very well know T s metabolites estradiol and DHT are needed in order to reap full beneficial effects of testosterone. Ts metabolites estradiol and DHT are needed in healthy amounts to experience the full spectrum of testosterones beneficial effects on (cardiovascular health, brain health...

I was wonderining what the appropriate DHT range is on TRT. Has anyone ever had an ideal range that they were happy at? Are there any links on this site for the appropriate DHT range:) ?

Been reading the forum for many months and finally registered to post a question that I have. Hoping someone here more knowledge can help me out and possibly share any experiences. Strongly considering taking on a journey of penis extending with extenders and pumps to add some size. I know I...