Excel Male Health Forum

The Leading Men's Health Forum for Testosterone Optimization & Hormone Wellness

Welcome to ExcelMale.com — the most trusted, expert-moderated community for men seeking evidence-based guidance on testosterone replacement therapy (TRT), hormone optimization, and total wellness. Since 2010, we've helped thousands of men take control of their health.

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Why ExcelMale? Evidence-Based Men's Health Information You Can Trust

Navigating testosterone replacement therapy and hormone health can be overwhelming. Conflicting information, outdated medical advice, and unqualified opinions flood the internet. ExcelMale.com was created to cut through the noise — providing a rigorously moderated space where men share real experiences, backed by clinical research and guided by genuine expertise.

Whether you're exploring TRT for the first time, optimizing your current protocol, managing side effects like elevated hematocrit or estradiol, or seeking to preserve fertility with HCG therapy, our community offers the knowledge and support you need. We discuss everything from injection frequency and bloodwork interpretation to lifestyle factors that affect testosterone levels.

"I founded ExcelMale after decades of personal experience with hormone optimization and seeing how difficult it was for men to find reliable, science-based information. Every man deserves access to knowledge that can transform his quality of life."

— Nelson Vergel, Founder & Author of Testosterone: A Man's Guide

Nelson Vergel brings over 20 years of clinical research experience, having worked with major pharmaceutical companies and authored definitive guides on testosterone therapy. As founder of DiscountedLabs.com and a recognized expert in men's health advocacy, Nelson ensures every discussion on ExcelMale meets the highest standards of accuracy and usefulness.

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Join thousands of men who have transformed their lives through evidence-based hormone optimization. Ask questions, share experiences, and learn from experts.

Anyone taking PCSK9 inhibitors (i.e. Repatha)?

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I have a scrip for Repatha but haven't yet started. Covered by insurance so cost not an issue. Was concerned that LDL would go too low and cause issues. Also, side effects. Read that it can cause hyperglycemia (diabetes). Any input would be...
MiPS2 Urine Test Better Than PSA?
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Chapters 0:49 What is the MiPS2 test and how does it work? 2:14 Can urine tests be used as a partial substitute for biopsies? 4:52 How does the 95% accuracy rate of urine tests affect the screening process? 7:17 What percentage of cancer is...
Diagrams: Accurate Androgen and Estrogen Measurement in Human Serum and Plasma
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* Probably the most challenging forms to quantify, due to their relatively low concentrations are the so called free forms. The free forms of all the hormones (shown in Figs. 1–3) are the hormones not bound to proteins, or conjugated to other...
Eating More Live Microbes May Boost Testosterone: What a New Study Found
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A new study published in Scientific Reports (Nature Publishing Group) has found a potential link between eating foods rich in live microbes—like those found in yogurt, kefir, kimchi, and other fermented foods—and higher testosterone levels in...
Where to Inject Testosterone: Intramuscular vs. Subcutaneous Injections
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No matter what kind of TRT your doctor has given you, a common question is where to inject testosterone. For decades, most men have injected their testosterone intramuscularly (IM), primarily into the glutes, quadriceps, or deltoids, using a 1 to...
Testosterone blood level is correlated with immune cell abundance in transgender young people on gender affirming hormones
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Sex hormones like estrogen and testosterone don’t just affect things like body shape or voice—they also play a role in how the immune system works. This is especially important for transgender people who take these hormones as part of their...
Estradiol: The "Other" Male Hormone
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Download slides (from my book "Beyond Testosterone"): Estradiol in Men Slides Estradiol in Men: The Stigma In the 2014 film The Other Woman, Cameron Diaz, Leslie Mann, and Kate Upton, portray three jilted females who discover they are...
Semaglutide Forum: Game Changer for Weight Loss
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Mark A. Moyad, MD, MPH & Martin M. Miner, MD, discuss the potential benefits of semaglutide, a newly approved weight-loss drug. Introduction: The Road to Real Weight Loss Solutions Host: This is another great segment with Dr. Marty Miner —...
Research Advances in Stem Cell Therapy for ED
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Stem Cell Therapy for Erectile Dysfunction: Current Evidence and Future Directions Erectile dysfunction (ED) is a prevalent condition affecting men worldwide, particularly those between the ages of 40 and 70. While conventional treatments such...
Managing the Testosterone-to-Estradiol Ratio in Men on TRT
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Managing the Testosterone-to-Estradiol Ratio in Men on TRT Introduction Testosterone replacement therapy (TRT) in hypogonadal men often leads to an increase in estradiol (E2) levels due to the aromatization of testosterone. This alters the...
Clomid (Clomiphene) Reduces IGF-1, a measure of Growth Hormone
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Summary of Study Findings: "Reduced IGF-1 Levels Following Clomiphene Treatment for Male Hypogonadism" (Journal of the Endocrine Society, 2025) Objective: To investigate whether clomiphene citrate—a selective estrogen receptor modulator used...
Treatment for Early Stage Prostate Cancer - Too Little or Too Much?
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[Note: Dr. Peter Carroll's presentation contains some graphic images for the purposes of medical education] Summary of the Transcript: Prostate Cancer Management and Evolving Practices Overview The speaker, a highly experienced urologist and...
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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