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Low Serum Testosterone in Outpatient Psych Clinics

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In a study that confirmed what seems so obvious to members of Excelmale, researchers have concluded that there is: "a lack of information on the prevalence of low testosterone in patients presenting with psychiatric complaints despite an...

Review of Studies of Testosterone to Assess Stroke Risk

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Although two of seven studies showed reduced stroke risk, the review could not come to a definitive conclusion. Among eight RCTs, a low frequency of stroke events (<5) was observed across both testosterone and control groups, thus...
Is Metformin a Miracle Drug ? : Nelson Vergel Explains
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Jay Campbell invited me to present a review of relevant data on the use of Metformin in men with and without diabetes. I hope you enjoy the work I put into explaining the data to clarify the myths and facts about this old drug that is creating...
FDA Rejects Test E Autoinjector, Xyosted
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The news article says: Antares Pharma had applied for approval of the product for men with physician-determined hypogonadism. The prefilled, single-use injector enables patients to self-administer testosterone at home instead of applying a...

Many Men Have Low Adherence to Topical Testosterone

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This news article on a talk at the American Association of Clinical Endocrinologists 2017 Conference surprised me Low adherence in men using testosterone gels Fewer than one in five hypogonadal men are adherent to prescribed topical...

NSAIDs Associated With Higher Testosterone Levels

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It's well established that opiates, over time, can suppress male androgen levels, leading to hypogonadism. Danish researchers recently examined the question of non-prescription analgesics and the relationship they had to male reproductive...
Metformin and PSA Levels: Does it Make a Difference?
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Metformin, the first-line antihyperglycemic, has been touted as something of a wonder drug with strong, anti-aging properties. A recent study conducted in Toronto was undertaken to determine if Metformin administration had any impact on PSA...

A Review of Testosterone Heart Attacks Based on Prescription Data

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Another paper in the Asian Review of Andrology reviews the studies of cardiovascular events that were based on analyzing prescription records. Each study is summarized and its weaknesses discussed. The conclusion is that most studies have found...

Fluoride Exposure Increases Estradiol Levels in Men

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New evidence suggests that fluoride may be an sexual hormone disruptor. From the abstract: We conducted a cross-sectional study in rural areas of Henan province in China to explore the interaction between the estrogen receptor alpha...

Waist Circumference: The Best Metric for Predicting Sexual Symptoms for Hypogonadal Men

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It's been well established that waist circumference is a useful, reliable predictor for cardiovascular risk. However, until earlier this year it was not certain what its value was in regard to sexual health/quality of life status in hypogonadal...

Testosterone and Stroke: No Connection Found, But More Research Called For

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While there have been studies of the role TRT may play in terms of cardiovascular disease, there have been few focusing specifically on TRT and stroke. Testosterone Replacement Therapy and the Risk of Stroke in Men: A Systematic Review...
Kidney Function: Cystatin C vs. Creatinine in Determining Risk
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Does adding the measurement of cystatin C to that of serum creatinine to determine estimated glomerular filtration rate improve its accuracy? That's the question asked by researchers who undertook a meta-analysis of 11 general population studies...
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