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Testosterone Reduces Fat by Decreasing Leptin Resistance

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“The novelty in our study stems from the fact that we simultaneously investigated the effects of testosterone in the context of a rigorous weight-loss program,”Mathis Grossmann,MD,PhD,FRACP,professor in the department of medicine at the...
Exposure to Phthalates Decreases Testosterone and Sperm Quality in Men
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Phthalates are used in a large variety of products, from enteric coatings of pharmaceutical tablets and nutritional supplements to viscosity control agents, gelling agents, film formers, stabilizers,dispersants, lubricants, binders, emulsifying...
Research Options for Erectile Dysfunction: Stem Cells and More
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The best paper to date summarizing research therapies for ED. I highly recommend reading the full paper below (attached file- Register on ExcelMale to open it). Abstract: Although oral phosphodiesterase-5 (PDE5) inhibitors are...
Water Retention Caused by Testosterone May Have Nothing to Do with Estradiol
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I get a lot of emails from men on testosterone replacement therapy (and/or HCG) that feel they have water retention (some with ankle swelling) and they are puzzled that their estradiol is low or below 35 micrograms/ml. They may have tried...

Testosterone Therapy Does Not Increase DVT and Pulmonary Embolism in 71,000 Patients

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Association Between Testosterone Replacement Therapy and the Incidence of DVT and Pulmonary Embolism: A Retrospective Cohort Study of the Veterans Administration Database. Sharma R, et al. Chest. 2016. Abstract BACKGROUND...

Testosterone Therapy Increased Fat Loss During Low Calorie Diet in Obese Men with low T

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Effects of testosterone treatment on body fat and lean mass in obese men on a hypocaloric diet: a randomised controlled trial. Ng Tang Fui M, et al. BMC Med. 2016. Abstract BACKGROUND: Whether testosterone treatment has benefits on...
Dihydrotestosterone- Man's Enemy or Friend ?
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DHT – FRIEND OR ENEMY? With the exception of estradiol, no hormone is more misunderstood than dihydrotestosterone, DHT. In fact, many men actually fear DHT, going out of their way to lower it and frustrate its biological activity. However...
Global Testosterone Deficiency Diagnosis and Treatment Patterns
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Although the measurement of serum testosterone levels is commonly used in the diagnosis of male HG, the cut-off values for low testosterone are not well defined and vary throughout the literature, ranging from 200–400 ng/dL, with 300 ng/dL being...
Testosterone Therapy Reduces Risk of Rehospitalization in Older Men With Low Testosterone.
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Androgen Therapy and Rehospitalization in Older Men With Testosterone Deficiency. Baillargeon J, et al. Mayo Clin Proc. 2016. OBJECTIVE: To assess whether the receipt of androgen therapy is associated with a reduced 30-day...
How to reverse sexual dysfunction caused by antidepressants
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In an open-label study of 1,022 patients with a mean 40 years of age, 59.1% reported antidepressant-associated sexual dysfunction.10 The study analyzed the following antidepressants: citalopram, paroxetine, venlafaxine, sertraline, fluvoxamine...

Testosterone Therapy in Opioid Induced Hypogonadism

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Testosterone therapy reduced pain and decreased opioid use in participants in this study. Over 18 months period, patients with Opioid Induced Hypogonadism (OIH) were identified in a tertiary referral pain center at the University of...

Topical Testosterone Adherence Low

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This news article on a talk at the American Association of Clinical Endocrinologists 2017 Conference surprised me. Fewer than one in five hypogonadal men are adherent to prescribed topical testosterone, new research indicates. The findings, from...
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