depression

I was reading that cabergoline increases dopamine so it can be used to treat depression. My brother's doctor prescribed him 0.25mg per week. What do you think ?

For years I have dealt with treatment resistant depression. TRT has helped a bit, but it’s no magic bullet. I’ve been reading up on a medication called Parnate. It’s an MAOI and is apparently very successful at treating TRD. The only issue is mainstream doctors are hesitant to prescribe it, so...

Just curious if anyone felt/had symptoms of depression after starting TRT? I am 10 years in on TRT and I have felt mentally tired and unmotivated most of the entire time... I sometimes thought it was High E or low Thyroid but no matter how much I lowered E or adjusted thyroid (Armour) it...

https://ir.compasspathways.com/news-releases/news-release-details/compass-pathways-announces-positive-topline-results COMPASS Pathways announces positive topline results from groundbreaking phase IIb trial of investigational COMP360 psilocybin therapy for treatment-resistant depression The...

COMPASS Pathways announces positive topline results from groundbreaking phase IIb trial of investigational COMP360 psilocybin therapy for treatment-resistant depression The largest randomized, controlled, double-blind psilocybin therapy study ever completed shows rapid and sustained response...

ABSTRACT Recent literature connects 5-alpha reductase inhibitors (5-ARIs) with neuropsychiatric adverse effects. Several clinical studies have indicated that former 5-ARIs users had a higher incidence of depressive symptoms and neuropsychiatric side effects than non-users. However, the...

I have noticed over the years like clock work a distinct drop in my mood (mildly depressed) on days where the sun is not out. I am more of one of the just “deal with it” guys and chalked it up to being normal but the positive effects sunlight has on my mood are too noticeable to ignore. I...

"A previous study showed that laughing gas improved depression symptoms one day after treatment. In the new study, the researchers wanted to see whether those effects were long-lasting and whether a lower dose could work as well. To do this, they recruited 24 patients with TRMD, who were...

All, I have friend who states that after orgasm from masturbation, will feel depressed, crappy, etc, but doesn't after orgasm during intercourse. He also asks about his refractory period. He states : "Vulnerable question -- does anybody else have a pretty severe refractory period? If so, have...

I am on my 4th week of TRT. My testosterone was at 265 from a GP lab. Started at 150, 50 3/week. I was having high anxiety on injection day so this week I started 30 EOD. My anxiety and depression is worse than when I started. I am now second guessing using TRT. Should I continue and get labs in...

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246784/ "Patients with thyroid disorders are more prone to develop depressive symptoms and conversely depression may be accompanied by various subtle thyroid abnormalities. Traditionally, the most commonly documented abnormalities are elevated T4...

I found that tramadol has a profound effect on my mood. It works by increasing serotonin, norepinephrine as well as working on one type of opioid receptor. Does anybody know of a similar AD?

This happened years ago and again in the last couple of weeks, so may be helpful for some. Various times in my life I have had depression and even after getting hormones tuned up there has been some nagging mild depression that creeps up. My T4 and T3 levels look good, but my TSH has sometimes...

I started TRT 5 weeks ago on 24mg/day subcutaneous injections of Test C (168mg/week). My doc put me on a relatively high dose because my SHBG is very high (maybe 2-3 standard deviations out of range), so much so that despite having naturally high TT levels, my FT was in the dumpster all the way...

I've been on TRT for almost 5 weeks (started the 5th week last monday). I didn't feel much during the first 3 weeks, but at the beginning of the 4th week I started feeling much better. Very focused and clear of mind in a way I'd never experienced before. I've had brain fog my entire life and...

Hey folks, I’ve been on 100mg Test-C 1x/wk for 4 weeks now. For the first 2-3 weeks I was feeling great overall, sense of wellbeing was way up, energetic, more motivated in the gym... just really doing well. The last couple of days have been... not that. I take my Test-C Thursday evening or...

At age 33, After years of depression, anxiety, fatigue, weight gain, sleep problems, ed, etc. I convinced my doctor to test my hormones. I was specifically interested in my Cortisol levels due to prolonged profound amounts of physical anxiety. The results of what he tested were; Total...

Taking my e2 from 72 to 11 and switching to Ed injections has done wonders for my anxiety panic attacks, I no longer feel anxious or emotional! I still have a dead sex drive? should I keep increasing my dose to see where I feel best at(been on this protocol for almost 6 weeks) I wanna see how...

The doctor put me on .5 mg of armidex Ed and my e2 went from 72 to 11 on a sensitive test! Range (8-28) my sex drive is still zero! I’m on daily prop injections of 15 mg Ed! someone recommended raising the dose to 175 mg should I?

PARTICIPATION NEEDED! Of those EM members that have taken nandrolone or are currently taking nandrolone alongside their TRT, we are conducting a small ExcelMale study to help determine the effect that nandrolone has on Total Testosterone, E2, Prolactin, SHBG, free T, and DHT while taking TRT...

I am really fed up with life! I haven’t masturbated in almost 12 months! My libido is non existence my brain is foggy my dick is numb!my anxiety is that of a womanI keep reading about how some people never get there sex drive back on trt! It’s over for me! I’ve taking three doses of .5 armidex...

Took two doses of .5 Adex day after t shot and not feeling much! On 62.5 e3d, I did a tren test cycle before someone told me my prolactin can still be elevated have the opportunity to get some caber should I add it?

Hey guys thanks for looking at my post. I have a fiance and shes amazing and wonderful and I love her to death the problem is I am dreading marriage life and feel like my life is over. I don't sleep with her that well. She falls asleep very easily unlike myself and I dread once having kids...

Just got my bloodwork had Ed for months! My e2 sensitive came back at 72! What would a good ai dose be? Have Arimidex on deck! On 125 mg of test!

Added 50 mg of Dhea on Sunday! And I have been sleeping like crazy,I feel a lot more aggressive in the gym,and improved mood! But my dick still feels numb and dosent stay hard for long, my sex drive is non existent! Should I lower or up Dhea dose heard of people getting better results with 100...

Hey everyone. I wanted to get input on what people's experiences with nandrolone have been, whether prescribed in low doses for joint pain, cachexia or just simply wanting to put on size. I have been prescribed nandrolone for the past year for joint pain through the Baylor College of Medicine...

I’m 47 years olds and suffered a depressive episode about 2 years ago. I was cycled through several Anti-depressants over several months and none worked. My testosterone was checked on 2 separate days in the morning and was found to be in the mid to low 100 range. I was started on TRT 1 year...

Hello ! I'm 33 years old. I've chronic fatigue, depression and no libido (and no morning erections. Erections are good if I get horny.) all of my life. I often feel nervous too much and experience anxiety (including social. I'm an introvert). I have apathy which progresses with time. Also I...

I believe something happened what I was afraid off. After starting TRT I became more and more dissatisfied with my job as time went on. In June I turned 35 and a mid life crisis hit me, I wanna retire, go to a gym, talk to women, but I have enough savings to last only two years without touching...

Realized this post was a bit long. I've summarized up top. Details further down. QUICK VERSION: Been feeling like crap for 3 months. Have had numerous expensive doc / specialist appointments, imaging scans, blood tests, and more tests, tests, testsssss etc with normal results. I saw doc on...

Hey guys, rewrote this post to be easier to follow. Started on TRT in mid June to help with libido, erection, mood, confidence and energy issues I've had for years. I have a pituitary tumor and treatments relative to that had not been helpful at all. I "tried" TRT before this - that is, I was...