fertility

Dr. Ajay Nangia is a professor and vice chair of urology at the University of Kansas Medical Center. Dr. Nangia explains the life cycle of sperm, the relationship between the germ cells of sperm and testicular cancer, fertility as it relates to testicular cancer, sexual health, and much more!

For the last 3 months I’ve added HMG twice a week along with my HCG. HMG is at 75ius each shot. I’ve been on TRT a long time and am trying to recover fertility without going off. For the vast majority of my time on TRT my FSH levels have been negligible (via bloodwork) at < 0.1. Now after 3...

Hey guys I have been on hcg 2000iu x3 a week since 27th January I've been told for years that I have primary hypogonadism but recent endocrinologist just says hypogonadism the Mrs and I are wanting a kid the semen analysis I did back in 21 said servere oligozoospermia and the recent test I have...

Hi friends , I am on TRT for 4+years now. Transcrotal cream 100MG testosterone a day.` ( 30 years old right now ) 2years ago my wife and I wanted to get pregnant so I did a sperm test and it came out I was azospermic .. Now I started a protocol of HCG 6500iu split in 2x 3250iu. The doc told me...

Comparison of Intratesticular Testosterone between Men Receiving Nasal, Intramuscular, and Subcutaneous Pellet Testosterone Therapy: Evaluation of Data from Two Single-Center Randomized Clinical Trials (2023) Parris Diaz, Rohit Reddy, Ruben Blachman-Braun, Isaac Zucker, Alexandra Dullea, Daniel...

I'm thinking of shifting from test cyp + hCG to enclomiphene or Clomid for fertility? How difficult and how long would the transition be?

I’m trying to regain fertility. Would adding Clomid to my protocol help additionally, I’m currently on HCG and HMG three times per week (each). HCG dosage is 1500iu each shot, HMG is 75iu each shot. I’m doing all of this while staying on TRT. I’m wondering if adding in the Clomid will also help...

Hey guys, I need your help. I got some severe testicular atrophy going on. from bigger than a walnut to smaller than an almond in over a year. Sometimes they disappear completely and the sack is shrunken. I never took Testosterone so I can't really figure out whats going on down there, but it...

Hi. I have been on TRT for some years now. Feeling great. My girl is days away from having our first child, looking forward to it. For those wondering, I was on 115 mg testosterone enanthate (split 2* week mondays am and thursdays pm) and 500iu hcg EOD from january to july. We first got...

Clomiphene citrate: A potential alternative for testosterone therapy in hypogonadal males (2023) M. Huijben | M. T. W. T. Lock | V. F. de Kemp | J. J. H. Beck | L. M. O. De Kort | H. M. K. van Breda Abstract Background Hypogonadism is a worldwide problem among men causing sexual, physical...

MP43-13 ENCLOMIPHENE IS ASSOCIATED WITH HIGHER PREGNANCY RATES WHEN COMPARED TO CLOMIPHENE IN INFERTILE MEN WITH LOW TESTOSTERONE (2023) Jordan Kassab, Juan Torres-Anguiano*, John Lindsey, Houston, TX; Jabez Gondokusumo, Sabine Itani, Mohamad Jabin, Bryan, TX; Larry Lipshultz, Houston, TX...

PD11-12 THE EFFECT OF CLOMIPHENE CITRATE ON PATIENT-REPORTED OUTCOME MEASURES (2023) Jessica Schardein*, Kia Fendereski, Zane Randell, Soren Keihani, Joshua Horns, James Hotaling, Salt Lake City, UT INTRODUCTION AND OBJECTIVE Clomiphene Citrate (CC) is a medication that can be used in...

MP79-17 VARIATIONS IN THE RETAIL PRICE OF HUMAN CHORIONIC GONADOTROPIN IN THE UNITED STATES (2023) Jake Miller*, Mitchell OLeary, Douglas Schneider, Charles Loeb, Lawrence Jenkins, Faysal Yafi, Orange, CA INTRODUCTION AND OBJECTIVE Urine-derived human chorionic gonadotropin (HCG) remains a...

Management Outcomes in Males With Hypogonadotropic Hypogonadism Treated With Gonadotropins (2023) Bahaa O. Sahib, Ibrahim H. Hussein, Nassar T. Alibrahim, Abbas A. Mansour Abstract Background Hypogonadotropic hypogonadism is an important cause of male infertility and loss of secondary...

THE AVAILABILITY OF GONADOTROPIN THERAPY FROM FDA-APPROVED PHARMACIES FOR MEN WITH HYPOGONADISM AND INFERTILITY (2023) Benjamin Borgert, MS, MPH, Michael Bacchus, MS, Alexandra Hernandez, MS, Shelby Potts, ARNP, Kevin Campbell, MD, MS Florida State University College of Medicine, University of...

Hi all, Firstly, thanks to Nelson and all on the forum for sharing the breadth of your knowledge online, it's taught and helped me so much. I was hoping I could pick your brains about a specific fertility protocol used by Dr. Ramasamy (interviewed by Nelson on podcast). Mainly, it is HCG...

Human in vitro spermatogenesis as a regenerative therapy — where do we stand? (2023) Meghan Robinson, Sydney Sparanese, Luke Witherspoon & Ryan Flannigan Abstract Spermatogenesis involves precise temporal and spatial gene expression and cell signaling to reach a coordinated balance between...

My guest today is one of the country’s most respected medical experts on TRT, otherwise known as testosterone replacement therapy. He’s an authority in using testosterone to help males improve muscle tone and strength, and enjoy more energy and improved health. Dr. Larry Lipshultz is a...

Hi all, Long time reader, first time poster. I am 27yo, been on replacement for about 2.5 yrs @ 120 mg/wk due to secondary hypo from pituitary damage (resulting from multiple concussions requiring hospitalization). As a natural, I could never produce more than 300ng/dl. Lowest test was 140 and...

Little background on me. I’m 38. Been on trt for almost 10 years. Many of those at very high levels of “trt” (200-250mg)… history of a few heavy steroid cycles. We have an 18 month old baby that took about 6 months to conceive while staying in trt and hcg/FSH (75iu 3x/week and 1000iu hcg 100...

Supernumerary sex chromosome abnormalities – new developments and future trajectories - A summary of the 2022 3rd International Workshop on Klinefelter syndrome, XYY and Trisomy X Claus H. Gravholt, Alberto Ferlin, Joerg Gromol, Anders Juul, Armin Raznahan, Sophie van Rijn, Alan D. Rogol, Anne...

Hi all, Is it possible that HCG run along with TRT could impact sperm motility? I had a decent count when running both, but motility was very low, could FSH be needed in sperm production to maintain adequate motility or is it something different? Currently off Test and running clomid to restore...

Hello Friends, Tomorrow, I will be commencing a "restart" protocol. I would like to make sure that I have everything correct before beginning. This will be my first time administering self treatment, so any feedback is greatly appreciated! Without further ado... Pre Treatment Test Results...

Ive read many anecdotes of people on TRT with HHCG long term or people who run cycles regainging fertility, but what about people who have run TRT only (no HCG, clomid, etc..) and regained fertility after years?

Hi everyone, I've been on a weekly protocol of 80mg test E (40 mg 2x per week) + 1,000 IU HCG (500 IU 2x per week) for about 12 months. I've done bloodwork twice in the last few months and surprised to still see my LH/FSH levels at basically 0. The key blood levels were as follows (generally...

The arcuate kisspeptin neuron population in a coronal brain slice. Image courtesy of the Herbison laboratory For many years, the ‘KNDy hypothesis’ has been the main mechanistic explanation of the pulsatile secretion of gonadotropin hormones. New research in Cell Reports proposes an...

Klinefelter Syndrome and Fertility Considerations by Dr. Ryan Yan Urology Residents, PGY-2 University of British Columbia.

Varicoceles: Overview of Treatment from a Radiologic and Surgical Perspective (2022) Helio V. Neves da Silva, BS Robert L. Meller, MD Eniola A. Ogundipe, MD Paul J. Rochon, MD, FSIR A testicular varicocele is the result of the expansion of the venous pampiniform plexus of the scrotum. Often...

"How can I increase my semen volume!?" is one of the most common questions I get from my patients. More importantly, does having MORE semen volume account for better sex? What are the ways to increase semen volume? Find out at the end of the video!

Hypogonadism is a deficiency in one of the testes’ two major functions: (a) testosterone secretion (endocrine function) and (b) spermatogenesis (reproductive function). The two types are known as primary (hypergonadotrophic) hypogonadism (testis failure) and secondary (hypogonadotrophic)...