fertility

Little background on me. I’m 38. Been on trt for almost 10 years. Many of those at very high levels of “trt” (200-250mg)… history of a few heavy steroid cycles. We have an 18 month old baby that took about 6 months to conceive while staying in trt and hcg/FSH (75iu 3x/week and 1000iu hcg 100...

Supernumerary sex chromosome abnormalities – new developments and future trajectories - A summary of the 2022 3rd International Workshop on Klinefelter syndrome, XYY and Trisomy X Claus H. Gravholt, Alberto Ferlin, Joerg Gromol, Anders Juul, Armin Raznahan, Sophie van Rijn, Alan D. Rogol, Anne...

Hi all, Is it possible that HCG run along with TRT could impact sperm motility? I had a decent count when running both, but motility was very low, could FSH be needed in sperm production to maintain adequate motility or is it something different? Currently off Test and running clomid to restore...

Hello Friends, Tomorrow, I will be commencing a "restart" protocol. I would like to make sure that I have everything correct before beginning. This will be my first time administering self treatment, so any feedback is greatly appreciated! Without further ado... Pre Treatment Test Results...

Ive read many anecdotes of people on TRT with HHCG long term or people who run cycles regainging fertility, but what about people who have run TRT only (no HCG, clomid, etc..) and regained fertility after years?

Hi everyone, I've been on a weekly protocol of 80mg test E (40 mg 2x per week) + 1,000 IU HCG (500 IU 2x per week) for about 12 months. I've done bloodwork twice in the last few months and surprised to still see my LH/FSH levels at basically 0. The key blood levels were as follows (generally...

The arcuate kisspeptin neuron population in a coronal brain slice. Image courtesy of the Herbison laboratory For many years, the ‘KNDy hypothesis’ has been the main mechanistic explanation of the pulsatile secretion of gonadotropin hormones. New research in Cell Reports proposes an...

Klinefelter Syndrome and Fertility Considerations by Dr. Ryan Yan Urology Residents, PGY-2 University of British Columbia.

Varicoceles: Overview of Treatment from a Radiologic and Surgical Perspective (2022) Helio V. Neves da Silva, BS Robert L. Meller, MD Eniola A. Ogundipe, MD Paul J. Rochon, MD, FSIR A testicular varicocele is the result of the expansion of the venous pampiniform plexus of the scrotum. Often...

"How can I increase my semen volume!?" is one of the most common questions I get from my patients. More importantly, does having MORE semen volume account for better sex? What are the ways to increase semen volume? Find out at the end of the video!

Hypogonadism is a deficiency in one of the testes’ two major functions: (a) testosterone secretion (endocrine function) and (b) spermatogenesis (reproductive function). The two types are known as primary (hypergonadotrophic) hypogonadism (testis failure) and secondary (hypogonadotrophic)...

https://www.clinicaltrials.gov/ct2/show/study/NCT05381831 Study Description Brief Summary: This is a prospective, non-blinded study of hypogonadal men with a history of testosterone therapy who became azoospermic or severely oligospermic and wish to avoid symptoms of hypogonadism during...

Considerations when treating male pubertal delay pharmacologically (2022) Rodolfo A. Rey ABSTRACT Introduction: Delayed puberty, usually affects psychosocial well-being. Patients and their parents show concern about genital development and stature. The condition is transient in most...