fertility

In this episode of Pearls & Perspectives, host Amy Pearlman, MD, is joined by renowned male reproductive specialists Larry I. Lipshultz, MD, and Dolores J. Lamb, PhD, to discuss the science, clinical value, and future of the male infertility laboratory. Drawing on decades of collaboration in...

From supplements to lifestyle advice, patients trying to conceive are surrounded by countless products and conflicting claims. How can they separate evidence-based recommendations from marketing hype? Ask a Sexpert! In this video, Dr. Sevann Helo discusses the role of supplements in fertility...

Who knew LOL! * Rena Malik, MD brings together leading experts Dr. Helen Bernie, Dr. James Smith, and Chief Medical Advisor of Swim Club Dr. Michael Eisenberg to discuss male infertility, declining sperm counts, and how lifestyle factors impact reproductive health. In this episode, Rena...

Nature staff discuss preliminary data on the effects of GLP-1 drugs on male fertility, plus a two-year trial of a brain-computer interface. Timestamps 00:18 Brain-computer interface makes a life-changing impactNature: At-home brain implant gives man with motor neuron disease his daily life...

Hi, I am trying to conceive and just had an appointment with new fertility doctor who is recommending a new protocol as follows; Fertility Protocol 50 mg Test Cyp per week 3000iu HCG x 3 per week Arimidex .5mg x 2 per week Current Protocol 14mg Test Cup daily (98mg week) 500iu HCG x 3 per...

Curated By Nelson Vergel | ExcelMale.com | Updated June 2026 If you've been on TRT for a while and still deal with flat libido or low motivation - even with testosterone in a solid range - there may be more happening than your T levels alone can explain. One underappreciated piece of that...

19:11 Why Enclomiphene Is So Unpredictable * the response is widely variable! Enclomiphene has quietly become one of the most prescribed men's health medications in America. It's marketed as the perfect alternative to testosterone replacement therapy (TRT): an oral medication that increases...

00:35 How Sperm Are Made: The 90-Day Sperm Lifecycle In this video, Dr. Natalie Crawford explains how to understand a semen analysis and what your sperm count, motility, morphology, and total motile sperm count can reveal about male fertility. Learn what normal semen analysis results...

* In male infants, luteinizing hormone (LH) and testosterone during minipuberty are present at levels similar to those in adults but subsequently become undetectable. This phenomenon was shown in infant boys more than 50 years ago. https://www.nejm.org/doi/full/10.1056/NEJMra2305989

Abstract INTRODUCTION AND OBJECTIVES: The use of testosterone replacement therapy (TRT) among men is rising leading to an increasing number of men with TRT induced azoospermia from hypothalamic-pituitary-gonadal (HPG) axis suppression. Human chorionic gonadotropin (HCG) is used to mitigate...

Abstract INTRODUCTION AND OBJECTIVES: To compare the impact of finasteride and dutasteride on semen parameters in young men treated for androgenic alopecia and to evaluate whether the duration of 5α-reductase inhibitor therapy affects sperm quality and hormonal profiles. METHODS: This...

Abstract INTRODUCTION AND OBJECTIVES: To evaluate FSH recovery rates and sperm production in men with testosterone therapy (TTh)-induced azoospermia treated with hCG alone versus hCG combined with clomiphene citrate, focusing on men with severely suppressed baseline FSH. METHODS...

Abstract INTRODUCTION AND OBJECTIVES: Testosterone therapy (TTh) is known to suppress spermatogenesis, but combination TTh with human chorionic gonadotropin (hCG) has been shown to maintain spermatogenesis in a small 26-patient case series. That study did not account for prior fertility (or...

* Despite these limitations, the findings of this review provide valuable guidance for clinical practice. The consistent benefit of combined hCG and FSH therapy in inducing spermatogenesis and achieving pregnancy supports its role as a first-line treatment for men with HH and infertility. Future...

https://www.urologyhealth.org/healthy-living/urology-care-podcast/sexual-health-podcasts/vasectomy-reversal-leads-to-couples-restored-fertility-with-dr-larry-lipshultz

Hi just received my semen analysis results and feeling a bit concerned. I’d love to hear the experience from other members in this group about conceiving while on TRT. A bit about me, 39 years old and have been on TRT for 5 years. Currently 14mg daily and HCG 500 IU 3 times a week. Was taking...

https://audioboom.com/posts/8890570-the-other-half-of-fertility-understanding-male-infertility Think infertility is just a women's issue? Think again. In this eye-opening episode of the Modern Parenthood Podcast, Dr. Dorette Noorhasan is joined by Dr. Andrew Sun. A trained urologist who...

* Randomized trials in obese hypogonadal men showed benefits including increased muscle mass, reduced fat, higher HDL, improved erectile function, and elevated TT. Older age (>55 years) was linked to reduced androgenic response. In late-onset hypogonadism, CC discontinuation led to relapse...

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The top threads on Gonadorelin were several years old, so forgive me if I am asking something that has been discussed already. I was prescribed Gonadorelin by my clinic, taking 0.5ml two times a week. Within 10 days, my testicular size completely returned after being on TRT for 18 months. My...

What Men on TRT Really Need to Know Curated By Nelson Vergel | ExcelMale.com | Updated March 2026 Key Takeaways • Masturbation does not cause long-term drops in testosterone -- this is well-established in the research. • Moderate masturbation is generally neutral to...

Does anyone know the dose for L-carnitine if taking IM or SubQ to improve semen parameters specifically morphology? On the Huberman podcast, he says "1 mig a day" but he must have misspoke. Does anyone know? Sperm Health and Male Fertility: What Every Man Needs to Know If you’re a man...

* Enclomiphene is one of two stereoisomers of clomiphene, the other being Zuclomiphene. Whilst zuclomiphene is more oestrogenic, enclomiphene is more anti-oestrogenic. Zuclomiphene is generally antigonadotropic due to its effects on oestrogen receptors, which leads to a subsequent reduction in...

In this episode, Dr. Kevin Chu and Dr. Justin Dubin delve into the American Urological Association (AUA) guidelines for male fertility. They emphasize the importance of concurrent evaluations for both male and female partners during infertility assessments, highlighting that these guidelines are...

Mohit Khera's personal experience with enclomiphene HPTA Conclusion

Hi, first time posting - had lots of value out of these forums and read most of the stickied and recommended logs for fertility restoration following TRT. Wanted to set out where I'm up to so far and history to (hopefully) get some advice or at least perspectives from the community. Also just to...

Take home message

HYPOGONADISM

This is critical! * Masterson emphasizes the importance of establishing a baseline semen analysis in men considering or already receiving testosterone therapy, as exogenous testosterone commonly suppresses sperm production and can complicate later fertility evaluation. * Explores the growing...

About the YO Home Sperm Test The YO Home Sperm Test is a private, easy way to assess sperm quality at home—no lab visit or mail-in required. Over 97% accuracy. Measures sperm concentration, motility, progressive motility, motile sperm concentration, and progressive motile sperm concentration...

Must listen for anyone interested in fertility especially when using exogenous T! * Why lab work and semen analysis interpretation require true infertility expertise In this exciting episode of Fertility and Other F Words, Dr. Amy Pearlman and Dr. Larry Lipshultz are joined by two leaders...