fertility

  1. madman

    Hypogonadism in men with prolactinoma: Diagnosis treatment, and management of persistent hypogonadism

    * Despite effective medical therapy with dopamine agonists and prolactin normalization, over 20 % of men with prolactinomas will remain with hypogonadism. * There are two suggested mechanisms for hypogonadism: central suppression of the hypothalamic-pituitary-gonadal axis caused by elevated...
  2. W

    Fertility protocol and nandrolone (Deca)

    Hi EM crew, This is my first post, so apologies if I do it incorrectly. Long story short I have been on self prescribe trt for 3 years due to low t and endos in Australia would not help me. I’ve messed around with nandrolone and for the last year using 50mg test and 150 nandrolone. I feel...
  3. madman

    Is Erectile Dysfunction a Sign of Infertility?

    Is erectile dysfunction (ED) a sign of male infertility? Not always — but it can sometimes point to underlying issues that affect both sexual health and fertility. In this video, Dr. Mike Hsieh, a urologist specializing in male reproductive health, and Dr. Jamie Stanhiser, a fertility specialist...
  4. madman

    The role of hypothalamic kisspeptin neurons in coordinating reproduction and metabolism

    * The discovery of kisspeptin neurons in the early part of this century revolutionized our understanding of reproductive regulation. These neurons project to and control GnRH neuronal excitability. More recently, arcuate kisspeptin neurons (KNDy) have been identified as the command neurons...
  5. madman

    Hormonal Therapy for Male Infertility: Clomid, Gonal F, HCG, Letrozole for oligospermia and low sperm count

    Dr. Ramasamy! 10:24- 12:03 (Case report Isotretinoin) https://pmc.ncbi.nlm.nih.gov/articles/PMC12619667/ Clomid, Gonal F, HCG, Letrozole for oligospermia and low sperm count
  6. madman

    Helen L. Bernie, DO, MPH, outlines clinical management of hypogonadism in fertility-desiring men

    * Finally, Bernie noted unresolved controversies in the field, including the optimal duration of fertility-preserving therapies, long-term outcomes of hybrid regimens combining testosterone with hCG, and best practices for sperm recovery after prolonged testosterone exposure. She emphasized the...
  7. madman

    Tailoring T Therapy For Fertility and Cardiometabolic Patients

  8. madman

    Preserving spermatogenesis in TD: innovations in replacement and stimulatory therapies

    * Fertility preservation remains an important consideration in the management of hypogonadal men. While exogenous testosterone therapy effectively alleviates symptoms, it suppresses the HPG axis and impairs spermatogenesis. Alternative therapeutic strategies—including short- acting formulations...
  9. R

    Can enclomiphene or tamoxifen have favorable effects on intratesticular testosterone

    Background to question: There are primarily 2 indications for using medication to increase LH stimulation of the testes during TRT: 1. Preservation of spermatogenesis (Fertility) 2. Preservation of intrinsic testicular production of testosterone (and estradiol) (avoidance of testicular...
  10. madman

    Own Your Testosterone with Natesto®

    https://www.natesto.com/ Save on NATESTO® With Eligible, commercially insured patients may pay as little as $25 per month*, per claim maximums apply. THE NATESTO® SAVINGS PROGRAM IS NOT HEALTH INSURANCE. *Manufacturer Terms: The Natesto Savings Program is not health insurance. Program...
  11. madman

    A Novel Combination Therapy for Testosterone Deficiency: Clomiphene Citrate With Oral TU Provides Symptomatic Relief With HPGA Preservation

    https://academic.oup.com/jsm/article/22/Supplement_4/qdaf320.053/8375197 https://www.vumedi.com/video/a-novel-combination-therapy-for-testosterone-deficiency-clomiphene-citrate-with-oral-testosterone-un/
  12. madman

    New Research Reveals Erectile Dysfunction Linked More to Blood Sugar Than Testosterone

    * “While testosterone certainly influences libido and general sexual well-being, its role in erectile function is less direct. Erections depend primarily on vascular and neurological integrity,” Zitzmann notes. * “When men present with sexual complaints — especially erectile dysfunction —...
  13. madman

    Raise Testosterone, Preserve Fertility: Enclomiphene vs Clomiphene vs TRT

    Enclomiphene can boost testosterone while preserving fertility. Board-certified urologist Dr. Justin Houman explains enclomiphene vs clomiphene and TRT, dosing, results (150–200 point T rise), side effects, labs, and who should use it. If you’re a younger guy with low T who still wants kids...
  14. madman

    TRT, Peptides & Fertility: A Deep Dive With Dr. Larry Lipshultz

    Step into the origins of modern men’s health and testosterone therapy with Dr. Alex Tatem as he sits down with his mentor, Dr. Larry Lipshultz — the pioneer behind male fertility surgery, testosterone research, and advanced hormone therapy. In this powerful conversation, they discuss: * How...
  15. madman

    Male Fertility Myths Busted: Professor Allan Pacey Reveals What Really Improves Sperm Health — Diet, Alcohol, Vaping, Stress, and More

    Semen analysis, hormonal and genetic testing! We spoke to our Patron, Professor Allan Pacey, who is one of the world's leading experts in male fertility about what actually makes a difference. We covered diet, smoking, vaping, alcohol, weight, supplements, extra tests, hot baths, tight...
  16. madman

    Effectiveness of ClOmipheNe CitRate for the management of mEn wiTh infErtility (CONCRETE): A randomized double-blind placebo-controlled trial

    Long overdue! * Clomiphene is a selective oestrogen receptor modulator that could stimulate testosterone secretion from the testes and boost spermatogenesis. Data from small randomised trials and observational studies suggest some benefit of using it to improve semen parameters in affected men...
  17. madman

    Enclomiphene compounded capsules

    https://www.cfspharmacy.pharmacy/enclomiphene-capsules Where we ship
  18. madman

    Testosterone and Fertility - Lifestyle Modifications to Raise Endogenous Testosterone

    Str8 from the master blaster! Dr. Lipshultz! Summary of Clinical Practice Implementation Life-Style Changes to Increase T
  19. madman

    Can You Take Testosterone and Still Have Kids? What Every Man Needs to Know

    TRT can change your hormones — but it may also shut down your sperm. In this video, Dr. Justin Houman (MD, board-certified urologist & men’s health specialist) explains how testosterone replacement therapy affects fertility, sperm count, and testicular function, how long recovery can take, and...
  20. madman

    Clomiphene or enclomiphene citrate for the treatment of male hypogonadism: a systematic review and meta-analysis of RCTs

    https://www.aem-sbem.com/article/clomiphene-or-enclomiphene-citrate-for-the-treatment-of-male-hypogonadism-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials/ ABSTRACT Objective This study aimed to evaluate the efficacy and safety of selective estrogen receptor modulators...
  21. madman

    The FDA Has Banned Compounded HCG— NuCare Pharmaceuticals Says Clinics Still Using It Could Face Serious Consequences

    * In March 2020, Federal law changed so that compounding several types of biological products, including HCG, became illegal.1 After the Biologics License Application (BLA) transition period ended, it became illegal to manufacture or market compounded HCG in the U.S. without a BLA. The FDA and...
  22. madman

    Testosterone, Semen Analysis, and Male Fertility: Expert Advice with Real-Life Journeys on Fertility

    Clomid is old news! hCG + FSH is where it's at for restoring/maintaining fertility on or off exogenous T! 500IU 3x/week will restore normal ITT. Protocol is compounded purified preparations of hCG/FSH (3000 IU hCG + 75 IU of FSH) injected subcutaneously 3X/week (M/W/F). Lipshultz reboot...
  23. madman

    Fertility, Testosterone & Men’s Health: Your Guide to HRT, Sexual Medicine, and Performance

    Welcome to Fertility and Other F Words, where Drs. Amy and Larry tackle fertility, sexual health, and everything in between—no topic too taboo, no question off limits. Dr. Amy Pearlman is a urologist and sexual medicine specialist dedicated to helping men and women optimize their sexual...
  24. madman

    Planting the Seeds of Fatherhood: Male Fertility Optimization and Fertility Planning

    In this episode, Dr. Kevin Chu and Dr. Justin Dubin discuss male fertility, addressing common concerns about infertility, the importance of understanding male factors, and when to seek help. They explore the impact of lifestyle choices, smoking, and testosterone therapy on fertility, as well as...
  25. E

    Starting Fertility Journey After Long-Term TRT – Seeking Insights

    Hey everyone, I’m 3 weeks into adding HCG (1,000 IU, 3x/week) after being on TRT (150–200mg testosterone cypionate/week) for the last 9 years. I split my TRT dose twice weekly. So far: Sperm analysis came back at zero. I’ve noticed a slight boost in energy and mood since starting HCG...
  26. madman

    Fertility-Focused Testosterone Therapy: Comparing hCG, Clomiphene, and TRT Strategies for Men

    * Use of hCG+TRT suppressed LH and FSH (p<0.05), whereas CC+TRT was associated with reduction in FSH only (p=0.02). However, at 6 months, CC monotherapy was associated with significant increases in LH and FSH (p<0.001). As expected, all three treatments were associated with substantial increases...
  27. madman

    Testosterone and LH Levels Are Falling in Healthy Men: New Evidence of a Global Reset in Male Hormone Health

    Meta-regression analysis, using testosterone serum levels as effect of the regression, the years of sample collection as covariates and subjects’ number, age and BMI as co-factors (BMI was available for 742 study groups). Statistical details are reported in Supplementary material PODCAST...
  28. madman

    Why Is Male Fertility Crashing Globally?

    Dr Michael Eisenberg is a professor of Urology at Stanford, a urologic surgeon, and a leading expert in male fertility and reproductive medicine. It's no secret that global population decline is accelerating, but what's driving it? Male fertility might be a major piece of the puzzle. So why...
  29. madman

    Healthy Ageing Men experience Decline of Sexual Function and Fertility Dependent on Increases of HbA1c within the Normal Range: the Longitudinal FAMe

    Author Block: Michael Zitzmann, MD,PhD, FRSM, FECSM, Claudia Krallmann, MD, Jann Cremers, MD, SABINE KLIESCH, MD, Simone Bier, MD. University of Muenster, Muenster, Germany. Disclosure Block: M. Zitzmann: None. C. Krallmann: None. J. Cremers: None. S. Kliesch: None. S. Bier: None. The...
  30. madman

    Meta-Analysis of Gonadotropin Treatment for Induction of Spermatogenesis in Men with Pathologic Gonadotropin Deficiency

    * Despite similar effects on serum testosterone and testicular volume, combined hCG/FSH appeared more efficacious than hCG alone at inducing spermatogenesis. Author Block: Christopher Alan Muir, MBBS1, Ting Zhang, PhD2, Veena Jayadev, MBBS2, Ann Conway, MBBS2, David J. Handelsman, MBBS, PhD...

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