fertility

  1. J

    Gonadorelin Works For Me. But How?

    The top threads on Gonadorelin were several years old, so forgive me if I am asking something that has been discussed already. I was prescribed Gonadorelin by my clinic, taking 0.5ml two times a week. Within 10 days, my testicular size completely returned after being on TRT for 18 months. My...
  2. Nelson Vergel

    Masturbation Frequency, Libido, and Morning Erections

    What Men on TRT Really Need to Know Curated By Nelson Vergel | ExcelMale.com | Updated March 2026 Key Takeaways • Masturbation does not cause long-term drops in testosterone -- this is well-established in the research. • Moderate masturbation is generally neutral to...
  3. J

    IM or SubQ Carnitine for Sperm Morphology

    Does anyone know the dose for L-carnitine if taking IM or SubQ to improve semen parameters specifically morphology? On the Huberman podcast, he says "1 mig a day" but he must have misspoke. Does anyone know? Sperm Health and Male Fertility: What Every Man Needs to Know If you’re a man...
  4. madman

    BSSM: Position Statement for the Potential Use of Enclomiphene in the Treatment of Male Hypogonadism

    * Enclomiphene is one of two stereoisomers of clomiphene, the other being Zuclomiphene. Whilst zuclomiphene is more oestrogenic, enclomiphene is more anti-oestrogenic. Zuclomiphene is generally antigonadotropic due to its effects on oestrogen receptors, which leads to a subsequent reduction in...
  5. madman

    "Fertility Law and Order: A Guide Through Male Fertility Guidelines"

    In this episode, Dr. Kevin Chu and Dr. Justin Dubin delve into the American Urological Association (AUA) guidelines for male fertility. They emphasize the importance of concurrent evaluations for both male and female partners during infertility assessments, highlighting that these guidelines are...
  6. madman

    Enclomiphene vs TRT: Where Does It Really Fit in Today’s HRT Landscape?

    Mohit Khera's personal experience with enclomiphene HPTA Conclusion
  7. J

    TRT: fertility restoration log and questions

    Hi, first time posting - had lots of value out of these forums and read most of the stickied and recommended logs for fertility restoration following TRT. Wanted to set out where I'm up to so far and history to (hopefully) get some advice or at least perspectives from the community. Also just to...
  8. madman

    Modern Semen Testing and Male Fertility Care

    This is critical! * Masterson emphasizes the importance of establishing a baseline semen analysis in men considering or already receiving testosterone therapy, as exogenous testosterone commonly suppresses sperm production and can complicate later fertility evaluation. * Explores the growing...
  9. madman

    YO Home Sperm Test over 97% accuracy: Simple Steps to Fertility Insights

    About the YO Home Sperm Test The YO Home Sperm Test is a private, easy way to assess sperm quality at home—no lab visit or mail-in required. Over 97% accuracy. Measures sperm concentration, motility, progressive motility, motile sperm concentration, and progressive motile sperm concentration...
  10. madman

    What a thorough male fertility evaluation actually looks like

    Must listen for anyone interested in fertility especially when using exogenous T! * Why lab work and semen analysis interpretation require true infertility expertise In this exciting episode of Fertility and Other F Words, Dr. Amy Pearlman and Dr. Larry Lipshultz are joined by two leaders...
  11. madman

    Hypogonadism in men with prolactinoma: Diagnosis treatment, and management of persistent hypogonadism

    * Despite effective medical therapy with dopamine agonists and prolactin normalization, over 20 % of men with prolactinomas will remain with hypogonadism. * There are two suggested mechanisms for hypogonadism: central suppression of the hypothalamic-pituitary-gonadal axis caused by elevated...
  12. W

    Fertility protocol and nandrolone (Deca)

    Hi EM crew, This is my first post, so apologies if I do it incorrectly. Long story short I have been on self prescribe trt for 3 years due to low t and endos in Australia would not help me. I’ve messed around with nandrolone and for the last year using 50mg test and 150 nandrolone. I feel...
  13. madman

    Is Erectile Dysfunction a Sign of Infertility?

    Is erectile dysfunction (ED) a sign of male infertility? Not always — but it can sometimes point to underlying issues that affect both sexual health and fertility. In this video, Dr. Mike Hsieh, a urologist specializing in male reproductive health, and Dr. Jamie Stanhiser, a fertility specialist...
  14. madman

    The role of hypothalamic kisspeptin neurons in coordinating reproduction and metabolism

    * The discovery of kisspeptin neurons in the early part of this century revolutionized our understanding of reproductive regulation. These neurons project to and control GnRH neuronal excitability. More recently, arcuate kisspeptin neurons (KNDy) have been identified as the command neurons...
  15. madman

    Hormonal Therapy for Male Infertility: Clomid, Gonal F, HCG, Letrozole for oligospermia and low sperm count

    Dr. Ramasamy! 10:24- 12:03 (Case report Isotretinoin) https://pmc.ncbi.nlm.nih.gov/articles/PMC12619667/ Clomid, Gonal F, HCG, Letrozole for oligospermia and low sperm count
  16. madman

    Helen L. Bernie, DO, MPH, outlines clinical management of hypogonadism in fertility-desiring men

    * Finally, Bernie noted unresolved controversies in the field, including the optimal duration of fertility-preserving therapies, long-term outcomes of hybrid regimens combining testosterone with hCG, and best practices for sperm recovery after prolonged testosterone exposure. She emphasized the...
  17. madman

    Tailoring T Therapy For Fertility and Cardiometabolic Patients

  18. madman

    Preserving spermatogenesis in TD: innovations in replacement and stimulatory therapies

    * Fertility preservation remains an important consideration in the management of hypogonadal men. While exogenous testosterone therapy effectively alleviates symptoms, it suppresses the HPG axis and impairs spermatogenesis. Alternative therapeutic strategies—including short- acting formulations...
  19. R

    Can enclomiphene or tamoxifen have favorable effects on intratesticular testosterone

    Background to question: There are primarily 2 indications for using medication to increase LH stimulation of the testes during TRT: 1. Preservation of spermatogenesis (Fertility) 2. Preservation of intrinsic testicular production of testosterone (and estradiol) (avoidance of testicular...
  20. madman

    Own Your Testosterone with Natesto®

    https://www.natesto.com/ Save on NATESTO® With Eligible, commercially insured patients may pay as little as $25 per month*, per claim maximums apply. THE NATESTO® SAVINGS PROGRAM IS NOT HEALTH INSURANCE. *Manufacturer Terms: The Natesto Savings Program is not health insurance. Program...
  21. madman

    A Novel Combination Therapy for Testosterone Deficiency: Clomiphene Citrate With Oral TU Provides Symptomatic Relief With HPGA Preservation

    https://academic.oup.com/jsm/article/22/Supplement_4/qdaf320.053/8375197 https://www.vumedi.com/video/a-novel-combination-therapy-for-testosterone-deficiency-clomiphene-citrate-with-oral-testosterone-un/
  22. madman

    New Research Reveals Erectile Dysfunction Linked More to Blood Sugar Than Testosterone

    * “While testosterone certainly influences libido and general sexual well-being, its role in erectile function is less direct. Erections depend primarily on vascular and neurological integrity,” Zitzmann notes. * “When men present with sexual complaints — especially erectile dysfunction —...
  23. madman

    Raise Testosterone, Preserve Fertility: Enclomiphene vs Clomiphene vs TRT

    Enclomiphene can boost testosterone while preserving fertility. Board-certified urologist Dr. Justin Houman explains enclomiphene vs clomiphene and TRT, dosing, results (150–200 point T rise), side effects, labs, and who should use it. If you’re a younger guy with low T who still wants kids...
  24. madman

    TRT, Peptides & Fertility: A Deep Dive With Dr. Larry Lipshultz

    Step into the origins of modern men’s health and testosterone therapy with Dr. Alex Tatem as he sits down with his mentor, Dr. Larry Lipshultz — the pioneer behind male fertility surgery, testosterone research, and advanced hormone therapy. In this powerful conversation, they discuss: * How...
  25. madman

    Male Fertility Myths Busted: Professor Allan Pacey Reveals What Really Improves Sperm Health — Diet, Alcohol, Vaping, Stress, and More

    Semen analysis, hormonal and genetic testing! We spoke to our Patron, Professor Allan Pacey, who is one of the world's leading experts in male fertility about what actually makes a difference. We covered diet, smoking, vaping, alcohol, weight, supplements, extra tests, hot baths, tight...
  26. madman

    Effectiveness of ClOmipheNe CitRate for the management of mEn wiTh infErtility (CONCRETE): A randomized double-blind placebo-controlled trial

    Long overdue! * Clomiphene is a selective oestrogen receptor modulator that could stimulate testosterone secretion from the testes and boost spermatogenesis. Data from small randomised trials and observational studies suggest some benefit of using it to improve semen parameters in affected men...
  27. madman

    Enclomiphene compounded capsules

    https://www.cfspharmacy.pharmacy/enclomiphene-capsules Where we ship
  28. madman

    Testosterone and Fertility - Lifestyle Modifications to Raise Endogenous Testosterone

    Str8 from the master blaster! Dr. Lipshultz! Summary of Clinical Practice Implementation Life-Style Changes to Increase T
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