Hormonal Therapy for Male Infertility: Clomid, Gonal F, HCG, Letrozole for oligospermia and low sperm count

madman · Dec 28, 2025

Dr. Ramasamy!

10:24- 12:03 (Case report Isotretinoin)

Spontaneous Pregnancy After Isotretinoin Use in a Man After Unsuccessful Microdissection Testicular Sperm Extraction - PMC

We report a spontaneous pregnancy in the partner of a man with non-obstructive azoospermia and histologically confirmed late maturation arrest following a failed microdissection testicular sperm extraction (micro-TESE). This patient was subsequently ...

pmc.ncbi.nlm.nih.gov

Clomid, Gonal F, HCG, Letrozole for oligospermia and low sperm count

madman · Dec 28, 2025

Thread 'Fertility maintenance or restoration in men before, during, and after TRT or AAS'

Sep 25, 2022

Fertility Preservation in Hypogonadal Men (2018)
Robert J. Carrasquillo and Ranjith Ramasamy

Introduction

Testicular failure is defined as the impairment or loss of both the endocrine functions of the testis (production of testosterone, or T) and exocrine function (production of spermatozoa). Testicular failure can result from the pathology of the testis itself or disorder at any point in the hypothalamic-pituitary-gonadal axis. Primary testicular failure is characterized by normal/low T in the presence of the elevated follicle-stimulating hormone...

madman · Dec 28, 2025

Thread 'Helen L. Bernie, DO, MPH, outlines clinical management of hypogonadism in fertility-desiring men'

Dec 26, 2025

* Finally, Bernie noted unresolved controversies in the field, including the optimal duration of fertility-preserving therapies, long-term outcomes of hybrid regimens combining testosterone with hCG, and best practices for sperm recovery after prolonged testosterone exposure. She emphasized the urgent need for larger, prospective, fertility-focused studies to guide future care.

Exogenous testosterone therapy and fertility are fundamentally incompatible.

In a talk at the 2025 Sexual Medicine Society of North America meeting in Grapevine...