trt

Analysis of Factors Improving Testosterone Gel Absorption and Efficacy Executive Summary The efficacy of transdermal testosterone replacement therapy (TRT) is heavily dependent on absorption dynamics, which are influenced by application site, post-application activities, and individual...

Last year fell into a whirlwind of low test like symptoms and consistently tested in the 350s total as a healthy and active 34 year old. In November and December I tested at 257 total / 35 free and 186total with 32 free. I was diagnosed with hypogonadism this month due to an issue found in MRI...

Hi all, I’ve recently been considering a move to Vancouver, but I’m not sure how easy it is to get TRT in Canada? I’m currently with Defy. Can they transfer my prescription? Do they have testosterone cream available? Curious if any Canadians can shed some light? Thanks!

I’m having a lot of issues with TRT. I started TRT at the end of May 200mg a week split into two injections. Also 600 UI of HCG. I never really felt great just spurts here and there. I did a blood test in July and my test was above 1500 and my estradiol was 40. My doctor had me start an AI which...

Hello, I have been lurking on this forum, looking at other cases and learning a little from them, but now I would like some guidance from you about my situation. At the age of 24, I was diagnosed with secondary hypogonadism, but it was a problem I had had before that age. (I related my symptoms...

My body has been wrecked since 2020. (got COVID19 June 2020, then hit by 2 hurricanes, August & October 2020). I am not sure if COVID was solely responsible for my current issues or the mix of two high stress environments caused me burn out to the point of adrenal failure which is what I believe...

Hi everyone, I’m looking for advice on the best way to structure my PCT after being on TRT for about 3 years, specifically whether enclomiphene should overlap with HCG or only after HCG is discontinued. Here’s my full background and current plan: TRT History On TRT for ~3 years total Started...

Ive experienced and have seen others who have had trouble dialing in, that take days or a week of their protocol and feel so much better.. Ive felt this myself and cant figure it out. Its not as simple as the dose being to high, because I took some days off then adjusted my dose down 25% and the...

Hey guys, I've been on TRT for about a year and wanted a way to visualize what's happening between doses and correlate it with how I feel day to day. I'm a dev, so I built what I wanted. Axis estimates testosterone levels between shots using a pharmacokinetic model. You can log symptoms and...

https://pubmed.ncbi.nlm.nih.gov/34445892/ Abstract Purpose: We sought to compare testosterone formulations and determine the degree that hematocrit increases vary by testosterone therapy formulation. As head-to-head trials are rare, network meta-analysis of the contemporary studies is the only...

Above is above is Most recent test at 28-30mg EOD. Below is test from end of July at 24-26mg EOD. Yes I feel like shit, and my shbg was 9.8! Im doing subq EOD and just recently am trying ED injections. I dont understand how my e2 has trippled? Does anyone have any input on this? What route...

I know I just started TRT at 140mg a dose with hcg. I'm never looking to go crazy then I need to and take more anabolic steroids. With under supervision, a lot of the risk can be mitigated? Even lets say I want to run TRT at least to change composition of how fat I look now to a bit fitted. From...

I've been on TRT for years, through the same clinic. I hadn't been taking my AI during that time, but the doc really, really felt that my numbers should be lower than 20, so he advised me to give it a try. Just did the blood work and yikes. T: 950 E: < 5 SHBG: 30 All of my other numbers are...

Hey guys, Looking for some advice on my TRT protocol. I'm 21, had testicular cancer last year (orchiectomy + chemo, now in remission). Been on TRT for about 3 months, trying to dial it in since I'm still having issues. Here's the situation: Complaint: Zero libido, some anhedonia, water...

https://www.urologytimes.com/view/mohit-khera-md-recaps-key-takeaways-from-fda-panel-on-trt-for-men Mohit Khera, MD, MBA, MPH, recaps key takeaways from an FDA expert panel discussion on testosterone replacement therapy for men. In a recent interview with Urology Times®, Mohit Khera, MD, MBA...

* This landmark event marks a pivotal moment in the advancement of men’s health and represents a major milestone for Marius, which has worked for years to elevate the scientific conversation surrounding testosterone and address longstanding misconceptions. * Shah will join an esteemed group of...

In this episode, Dr. Brandon & Dr. Morgentaler talk about the emerging evidence that testosterone therapy may be safe—and even beneficial—for men with metastatic prostate cancer. Chapters 00:11 – Testosterone Use in Metastatic Prostate Cancer Dr. Morgentaler introduces the surprising...

I am 46 years old and I`ve been on TRT for around 7 years. I decided to try and stop TRT because It has been mostly ok but I struggle with libido and sensitivity down there as well as difficulty ejaculating and reaching orgasm although my testosterone was quite OK between always between 700 -...

Hi guys, Bit of context, I’m a 28-year-old male. I started TRT because of brain fog and wanting better muscle gains. When I first started Test Cypionate at 100 mg per week divided into 3 injections, I felt great for the first few weeks. But then I developed insomnia, bloating, and ED. I...

@Nelson Vergel We need you here! https://www.fda.gov/patients/fda-expert-panels/fda-expert-panel-testosterone-replacement-therapy-men-12102025 Location: FDA White Oak Campus, 10903 New Hampshire Ave., Building 31, Great Room, Silver Spring, MD 20993-0002. There will be limited seating...

* SubQ injectable TRT is a relatively novel therapy aimed at minimizing the drawbacks associated with IM TRT while potentially offering steadier absorption. * This IRB-approved study (22111501) investigated our institution’s use of non-proprietary SubQ TRT with testosterone cypionate (T CYP)...

Shalin Shah is the CEO of Marius Pharmaceuticals and a leader in metabolic and men’s health. He spearheaded the FDA approval of the first oral testosterone therapy for men with low testosterone. With a mission to make hormone health more accessible, Shalin advocates for education, innovation...

Hey guys….new here and just looking for some guidance. I’m a 51 year old male who I consider in pretty good shape. 5’9” and 180 lbs. I do CrossFit 3-4 days a week. I take no prescription medications. Only a couple of supplements. Very healthy with no risk factors for ED. Beginning of this year...

Professor Michael Zitzmann We also know hematocrit can be increased by testosterone preparations. It depends on the preparation, and we think that there is data that shows that the threshold of 52-54% should not be surpassed, and men should be controlled for the hematocrit especially in the...

* Miner emphasized that TRAVERSE has reshaped the safety narrative around testosterone replacement therapy (TRT), easing concerns about cardiovascular and prostate risks. Many men with hypogonadism—who often suffer from fatigue, mood changes, and depression—are now more open to discussing TRT as...

I have been taking 200mg of cypionate twice weekly for 12 weeks. I am "supposed" to be take 200mg bi-weekly. My doctor wants a blood test. How long after stopping the injections will my levels drop. Should I do PCT or just slowly go back to bi-weekly?

Hey all, I'm new here so I hope this question is ok as I've not found much on this low level of dosage. I've been dealing with high e2 symptoms for a while and my E2 is creeping up (currently 48pg/ml). Not super high but very high for me as I started trt at 15pg/ml. I just aromatize kinda...

48:03: How to prescribe and access Kyzatrex How to Prescribe Through selected compounding and mail-order pharmacies, not at chain stores (CVS/Walgreens), keeping costs low and access high. Prescriptions are cash pay but often below compounding pharmacy prices—no insurance required. Another...

Prof. Dr. Omer Raheem Post-Myocardial Infraction TRT Conclusion

Enclomiphene can boost testosterone while preserving fertility. Board-certified urologist Dr. Justin Houman explains enclomiphene vs clomiphene and TRT, dosing, results (150–200 point T rise), side effects, labs, and who should use it. If you’re a younger guy with low T who still wants kids...