trt

  1. madman

    Subcutaneous Testosterone Injections: A Safer, Smoother Low T Solution for Men With Hypogonadism

    * SubQ injectable TRT is a relatively novel therapy aimed at minimizing the drawbacks associated with IM TRT while potentially offering steadier absorption. * This IRB-approved study (22111501) investigated our institution’s use of non-proprietary SubQ TRT with testosterone cypionate (T CYP)...
  2. madman

    Why Testosterone Decline Is the New Health Epidemic

    Shalin Shah is the CEO of Marius Pharmaceuticals and a leader in metabolic and men’s health. He spearheaded the FDA approval of the first oral testosterone therapy for men with low testosterone. With a mission to make hormone health more accessible, Shalin advocates for education, innovation...
  3. S

    TRT Ups and Downs

    Hey guys….new here and just looking for some guidance. I’m a 51 year old male who I consider in pretty good shape. 5’9” and 180 lbs. I do CrossFit 3-4 days a week. I take no prescription medications. Only a couple of supplements. Very healthy with no risk factors for ED. Beginning of this year...
  4. madman

    TESTOSTERONE: A SAFETY UPDATE 2025

    Professor Michael Zitzmann We also know hematocrit can be increased by testosterone preparations. It depends on the preparation, and we think that there is data that shows that the threshold of 52-54% should not be surpassed, and men should be controlled for the hematocrit especially in the...
  5. madman

    Testosterone Controversies: Lessons Learned from TRAVERSE 2025

    * Miner emphasized that TRAVERSE has reshaped the safety narrative around testosterone replacement therapy (TRT), easing concerns about cardiovascular and prostate risks. Many men with hypogonadism—who often suffer from fatigue, mood changes, and depression—are now more open to discussing TRT as...
  6. L

    How long does testosterone drop after stopping

    I have been taking 200mg of cypionate twice weekly for 12 weeks. I am "supposed" to be take 200mg bi-weekly. My doctor wants a blood test. How long after stopping the injections will my levels drop. Should I do PCT or just slowly go back to bi-weekly?
  7. M

    1mg microdosing aromasin for mild E2 increase with symptoms

    Hey all, I'm new here so I hope this question is ok as I've not found much on this low level of dosage. I've been dealing with high e2 symptoms for a while and my E2 is creeping up (currently 48pg/ml). Not super high but very high for me as I started trt at 15pg/ml. I just aromatize kinda...
  8. madman

    Testosterone Breakthrough: A New Testosterone Solution Rocking the HRT World

    48:03: How to prescribe and access Kyzatrex How to Prescribe Through selected compounding and mail-order pharmacies, not at chain stores (CVS/Walgreens), keeping costs low and access high. Prescriptions are cash pay but often below compounding pharmacy prices—no insurance required. Another...
  9. madman

    Testosterone Replacement in Cardiac Patients and Sexual Health

    Prof. Dr. Omer Raheem Post-Myocardial Infraction TRT Conclusion
  10. madman

    Raise Testosterone, Preserve Fertility: Enclomiphene vs Clomiphene vs TRT

    Enclomiphene can boost testosterone while preserving fertility. Board-certified urologist Dr. Justin Houman explains enclomiphene vs clomiphene and TRT, dosing, results (150–200 point T rise), side effects, labs, and who should use it. If you’re a younger guy with low T who still wants kids...
  11. T

    DHT Cream dosing help

    Hello, I got 10% DHT cream in lipsomal base 50ml. How much of cream do I use per day? There is no instructions or dosing. Im using it for the purpose of PFS. Im on TRT cream as well. Thanks
  12. madman

    Can You Take Testosterone and Still Have Kids? What Every Man Needs to Know

    TRT can change your hormones — but it may also shut down your sperm. In this video, Dr. Justin Houman (MD, board-certified urologist & men’s health specialist) explains how testosterone replacement therapy affects fertility, sperm count, and testicular function, how long recovery can take, and...
  13. madman

    Free vs Total Testosterone: What Most Men (and Doctors) Get Wrong

    Free testosterone vs total testosterone — which one actually matters? In this video, Dr. Justin Houman, board-certified urologist and men’s health specialist, explains the key difference between total testosterone and free testosterone, how sex hormone binding globulin (SHBG) affects your...
  14. madman

    Undecatrex™ an FDA-approved authorized generic version of Kyzatrex® is now available

    An Authorized Generic version of Kyzatrex has been approved. * An Authorized Generic is a prescription drug that is produced by a brand company under a New Drug Application (NDA) and marketed as a generic under a private label. It is identical to the branded product in appearance and has...
  15. madman

    KYZATREX® Safe for your liver: Lymphatic Absorption

    * The good news is that KYZATREX was specifically designed to be absorbed lymphatically. This means it bypasses your liver avoiding the liver toxicity associated with oral testosterone medications of the past. Kyzatrex® (testosterone undecanoate) an oral testosterone therapy Taken...
  16. madman

    Dr. Shalender Bhasin: Optimizing the Diagnosis and Treatment of Hypogonadism 2025

    Nelson's house u heard it here first! Dr. Shalender Bhasin! * over the past 4 decades he has become a global leader in the biology of androgens, sarcopenia and aging related functional decline, his research has shaped clinical guidelines, its informed public health policy particularly around...
  17. T

    Any reputable sources for DHT?

    Hello all. Im dealing with PFS symptoms from the use of finasteride. I went on TRT cream for symptom relief, but did not get much DHT related symptom relief. Looking to add DHT gel to my protocol. Anybody experienced benefits in regards to PFS symptoms with the use of DHT gel? Please advise...
  18. T

    Is my ED physical, psychological or hormonal?

    Good morning all, Hope everyone is well. I am a 33 year old man, currently weighing 88kgs and height 1.83 cm (6 foot). I have been battling erectile dysfunction for 10 years or so, starting from when I was 22 or 23 years old. I have posted about my journey in this thread (Help with...
  19. madman

    The role of testosterone in cardiovascular health: benefits and risks of replacement therapy

    * This paper examines testosterone’s dual role in the cardiovascular system. Low levels are linked to increased risks of heart failure (HF) and coronary artery disease (CAD), while testosterone replacement therapy (TRT) can improve heart function, exercise tolerance, and metabolic health...
  20. D

    Impact of TRT and Supraphysiological Testosterone Doses on Biological Aging

    I've seen that some people measure their rate of aging using tools like genetic or epigenetic clocks (e.g., DNA methylation age). I'm wondering how different testosterone dosages, from standard TRT levels up to supraphysiological doses, might affect the speed of aging as measured by these...
  21. madman

    Why Is Your Man So Tired? The Real Impact of Low Testosterone on Intimacy & Marriage

    Is your man more tired than usual, moodier, or pulling away from intimacy? You’re not imagining it. In this episode, I’m joined by Dr. Joshua Gonzalez: a board-certified urologist and sexual medicine specialist to talk about the low testosterone epidemic and why men’s midlife health is often...
  22. F

    Kyzatrex Health Canada approval

    Has anyone seen any updates on Kyzatrex approval by Health Canada? All I can find is approval was expected by the end of 2025 Q2 and we are closing in on Q4
  23. madman

    Testosterone at Home: Easy Step‑by‑Step Guide to Collecting Blood with the Tasso® Device | Hims HRT Journey

    Sample collection procedure Welcome to Testosterone by Hims. Learn how to collect blood samples at home with the Tasso® device as the first step of your testosterone journey. This tutorial will show you how to draw blood safely and comfortably in about 20 minutes and seamlessly get...
  24. J

    Thinking about TRT and could use some guidance

    Hello All, Long time lurker first time poster here. First of all thanks to all the people who make this great resource available. I have had many questions answered and the information here has helped me to better formulate the questions that remain. This is a long post with a lot to unpack so...
  25. madman

    Does TRT Affect 4Kscore? New Study Reveals Surprising Impact of Testosterone on Prostate Cancer Screening

    * Our study found that men receiving TRT had significantly lower 4Kscores and PSA levels despite equivalent age and prostate volumes along with similar rates of clinically significant prostate cancer. These findings suggest that 4Kscore may be less affected by exogenous testosterone than PSA...
  26. madman

    Testosterone Deficiency After Prostate Surgery: Why Up to 1 in 3 Men Develop Low T After Radical Prostatectomy

    * TD develops in 20-30% of men within 2-4 weeks of RP, with more profound TT suppression among those with higher-grade disease (e.g., Gleason 4+3). Mechanisms include retrograde venous shunting, DVC-induced intratesticular venous pressure elevation, and pneumoperitoneum-induced testicular...
  27. C

    Less estradiol with faster-acting testosterone?

    Just putting this out for discussion and comments. There have long been anecdotal suggestions that faster-acting testosterone leads to lower overall levels of estradiol. In particular, it's often claimed in regard to using testosterone propionate versus longer esters such as cypionate. It could...
  28. S

    Giving up on TRT after 5 years

    After 5 years of HRT/TRT I'm packing it in. I now have BPH, I'm on a statin and repatha, I take cialis and an alpha blocker... testosterone and hcg, occasionally arimidex. The thing is that I didn't need any of these drugs 6 years ago before I started TRT so why am I on them now? I bought...
  29. Fernando Almaguer

    Factors Involved in Immune Resilience and Longevity

    This guys channel is fascinating. N of 1 type experimentation with diet to see how blood markers correlate with increase or decrease of certain foods. He has great guests as well. This lecture explores immune resilience, a crucial factor for health and longevity that counteracts...
  30. madman

    Uncovering Varicoceles – The Hidden Men’s Health Issue Impacting 15% of Men and Their Fertility

    In this episode, the hosts explore the often-overlooked topic of varicoceles. Dr. Justin Houman sheds light on the prevalence of this condition, affecting approximately 15% of men, and discusses the challenges in diagnosing it. Dr. Houman also delves into the significant implications varicoceles...
  31. madman

    State-of-the-Art Lecture: Updates on testosterone replacement therapy CUA 2025

    Nelson's house.....you know where it's at! Conclusions
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