trt

JAMA Medical News Director Jennifer Abbasi and Associate Managing Editor Kate Schweitzer discuss “Testosterone Therapy: Does New Evidence Warrant Broader Prescribing?”

But while Khera supports screening, he said he worries about inappropriate use of TRT. “I wouldn’t treat someone with TRT if they weren’t symptomatic” or had normal testosterone levels, says Khera, who helped publish seminal research on TRT and in 2025 led a U.S. Food and Drug Administration...

Standardized testosterone assays are available and improve accurate diagnosis of hypogonadism and ensure men who need treatment receive it. The use of a testosterone assay that has been certified by the CDC HoST program ensures that the assays have been standardized and “harmonized”; results...

* The particular threshold of 700 ng/dL chosen for this study demonstrated the greatest, most significant difference in CAG repeat length between the two groups. * In the cohort with complete follow-up data (n=75), patients whose testosterone levels superseded 700 ng/dL following therapy...

I just got a bone scan and have osteopenia in spine and dual femurs. I’m not on TRT. I have been doing weight-bearing exercises for years and been on calcium, etc. not sure if it’s from chemo or testosterone that’s been in the 350 range the past four years or so I was wondering if TRT...

https://www.bcm.edu/healthcare/clinical-trials/h-56187 Description An Open-Label Multiple-Dose, 52-Week Study to Evaluate the Safety, Pharmacokinetics, and Efficacy of XYOSTED® for Testosterone Replacement in Male Adolescents (ages: 12 to <18 years) With Conditions Associated with Deficiency...

* Bhasin noted that, like fellow academics and endocrinologists, he has historically been cautious around testosterone therapy. “In the last 5 years or so, we’ve learned a lot more, and I’ve changed my position,” he said. “On one side, it’s very rigid, and on the other, it’s touted as the cure...

https://www.linkedin.com/pulse/new-official-german-mens-health-portal-section-fcpfe Prof Dr med Dr hc Michael Zitzmann, MD. PhD, FRSM https://www.maennergesundheitsportal.de/themen/testosteronmangel-bei-maennern/

https://endo2026.endocrine.org/searchGlobal.asp Background Testosterone therapy is widely used for male hypogonadism but suppresses gonadotropins, reducing intratesticular testosterone and impairing spermatogenesis. These effects contribute to testicular atrophy, infertility, and increased...

I’ve searched this forum and several others trying to find a situation that matches mine, but I haven’t found anything that really lines up, so I’m posting here hoping someone sees something obvious that I’m missing. I’m a boxer with 15+ years of training. For the last 4 years I’ve been battling...

* TRT does not increase MACE risk in men with confirmed organic hypogonadism when titrated to physiological levels. Non-MACE signals warrant vigilance rather than contraindication. Metabolic optimisation should precede TRT in functional hypogonadism. Individualised monitoring and careful patient...

In this episode, Dr. Brandon and Dr. Morgentaler talk about navigating sexual differences in relationships, the latest evidence supporting testosterone therapy after prostate cancer treatment, and practical ways couples can rebuild intimacy and sexual confidence during recovery. 00:00 –...

* The program will launch in July 2026 and will initially be available in 37 states. * Life MD’s platform is designed to remove those barriers by combining clinically appropriate virtual evaluation, lab-based diagnosis, ongoing clinical support, and access to home delivery of an FDA-approved...

https://mariuspharma.com/news/marius-pharmaceuticals-applauds-fdas-proposed-testosterone-labeling-updates-as-a-turning-point-for-mens-health/ The FDA’s second major labeling update in 16 months — after its February 2025 removal of the cardiovascular boxed warning — marks a historic...

Starting in December 2025 I began a 160mg TRT weekly protocol that has HCG 250mg monday wednesday friday however the clinic had closed for approximately two weeks. I ended up taking a test booster called EVL Test that has the following Vitamin D3- 50 Mcg Vitamin B6- 11mg Magnesium 160 mg...

* We studied 394 men aged 22–76 years with primary (n=132), secondary (n=96), or functional (n=166) hypogonadism treated for up to 7 years with T-gel (1–3 actuations/day; n=168), TU 1000 mg intramuscularly every 10–14 weeks (n=142), or hCG 1500 IU subcutaneously twice weekly (n=84). *...

Born for this! https://www.renalandurologynews.com/features/mohit-khera-testosterone-therapy-for-men/ https://www.excelmale.com/threads/once-weekly-hcg-helps-preserve-fertility-in-men-on-testosterone-therapy-largest-study-yet.34086/

My Test dosage is 70 Mg/ week split in to two doses. I don’t have high estrogen or symptoms. But my immunity has dropped considerably and I am getting frequent cold/cough/UTI while on TRT. Had to take antibiotics and takes a long time to cure. I believe this is because of TRT. In terms of life...

I currently take 1500 IU of HCG weekly Split into 3 shots of 500IU each and they are taken on Monday/Wednesday/friday. I also take testosterone year round and add in some other compounds. I take HCG solely for testicular size and the benefits I feel on it for libido and increasing penile...

* Immunoassays show acceptable accuracy for total T but are unreliable for free T measurement [19,20]. * As previously noted, the main limitation of free T evaluation in clinical practice is the poor accuracy of the available immunoassay methods [19]. To address this issue, several...

Another one under the belt for Dr. Bhasin! https://edhub.ama-assn.org/jn-learning/audio-player/19061825 Interview with Shalender Bhasin, MBBS, author of Testosterone Treatment in Prostate Cancer Survivors With Hypogonadism: A Randomized Clinical Trial, and Peter C. Albertsen, MD, author...

Hi guys, I am 8 weeks into trt, enanthat 40mg e3.5d subQ. Started low, as I was having a history 6 years ago with trt and elevated hematocrit. My results came in and I was shocked. HCT already came back at 52.2 and total T at 11.8ng/ml which was surprisingly high as well for that low dose...

Shalin Shah explains how testosterone serves as a key biomarker for overall health and outlines common symptoms that indicate testing is needed: including fatigue, muscle loss, and decreased libido. He emphasizes that while lifestyle factors like diet, sleep, and exercise are foundational...

Hi team. Been on a TRT journey for a year. One of the biggest takeaways I've learned here is to stay the coarse, try not to change dosage and timing often, things will stabilize. But, in doing so I am feeling off, constantly...its been going on for 6 months. After months of trial and...

* The CDC’s Clinical Hormone Standardization Programs standardize the total testosterone assay so that results are accurate, comparable, and clinically meaningful wherever they are performed * By calibrating assays to a common reference method and enforcing stringent performance criteria, CDC...

Was bound to happen sooner or later! There was still some limited back stock floating around. I am sitting on numerous vials and have some Delatestryl left to boot. All we have know are slim pickings the two generics Hikma TE and Taro TC. Even then everyone is going to be stuck with the Taro...

0.30 ml enanthate E3D put me at 742 trough free T PMOL, Total T 30nmol and shbg 8 (single digit shbg always) I felt really good on this dose but then i lowered to 0.20 E3D, and i started getting a bit of brain fog, less drive and motivation. My urologicst doesen’t keep people over the reference...

Nothing ground breaking here as the majority of men will stick with the go to medium acting esterified TC/TE! Flexible dosing and easily titrated are key here let alone weekly injections whether once weekly or more frequently take the cake when it comes to taking advantage of the anabolic...

48-Position Custom Deep Well Plate For In Vitro Equilibrium Dialysis at a 1:1 Sample to Buffer Volume Ratio * CDC scientists have developed a new design for a multi-well dialysis microplate for equilibrium dialysis. The unique design accommodates a 1:1 buffer to sample ratio and provides...

I’m on the fence about starting TRT. A little backround about me. 31(M) at roughly 16% BF with a healthy overall lifestyle. I workout 4x per week, eat healthy for the most part, and sleep 8 hours per night. Supplements I’m currently taking are a multivitamin, vitamin D, magnesium, zinc, and...