testosterone

  1. madman

    Sexual Function and Testosterone in Men Treated with Buprenorphine: A Systematic Review of the Literature

    * The available literature suggests BUP may impact male sex hormones to a lesser degree than full-agonist opioids. High-quality research is needed to explore the relationship between BUP and OIH in comparison to full opioid agonists and non-opioid controls...
  2. madman

    The Importance of Baseline Testosterone and Testosterone Recovery in High Risk and Locally Advanced Prostate Cancer

    https://www.urotoday.com/conference-highlights/apccc-2026/168579-apccc-2026-the-importance-of-baseline-testosterone-and-testosterone-recovery-in-high-risk-and-locally-advanced-prostate-cancer.html Taken together, the absence of testosterone recovery seems to be associated with worse overall...
  3. madman

    A Breast Cancer Oncologist Challenges Everything We Were Told About Hormones

    For years, many women have been told that hormones after breast cancer are simply off the table. But what if the evidence is more nuanced than that? In this episode, Dr. Kelly Casperson sits down with medical oncologist, researcher, and sex therapist Dr. Linda Bosserman to discuss estrogen...
  4. madman

    High-value laboratory testing in erectile dysfunction, reduced sexual desire,and suspected hypogonadism

    * Male sexual symptoms are biologically heterogeneous and clinically nonspecific. Erectile dysfunction, reduced sexual desire, impaired spontaneous erections, and broader androgen-deficiency symptom clusters may arise from vascular, psychogenic, relational, neurological, metabolic, endocrine, or...
  5. madman

    Want To Improve Your Testosterone? Here's A Guide To What Actually Works (TRT Vs Lifestyle Changes)

    Testosterone is the talk of the town. Who should consider treating it and who shouldn't, and can lifestyle changes and supplements really make a difference? In this episode of MAN ALIVE, leading men's health specialist & GP Dr Jeff Foster gives a simple explanation of the benefits and...
  6. madman

    Regenerative Restoration of Physiologic Testosterone Production Using 3D Bioprinted Human Induced Pluripotent Stem Cell Derived Leydig Cells

    Leydig Cell Implants! 11:55-24:00 Testosterone Deficiency Generation & Transcriptomic Validation of hiPSC-Derived Leydig Cells Generation of an Expandable Leydig Progenitor Population Physiologic-Conditions Drive Functional Leydig Maturation 3D Bioprinted...
  7. madman

    Men’s Sexual Health: What Erectile Dysfunction Can Reveal

    If you’re searching late at night about erectile dysfunction, low testosterone, libido, or fertility, you’re not alone—and those questions can be an important clue about your overall men’s wellness. In this episode of Baptist HealthTalk, host Dr. Anthony Gonzalez sits down with Dr. Justin...
  8. madman

    What Every Man Should Know About the New TRT Label

    In this episode, Dr. Kevin Chu and Justin Dubin discuss the recent updates to testosterone therapy labels, debunk myths about prostate cancer risks, and explore the future of testosterone treatment and regulation. They emphasize the importance of evidence-based practice and evolving medical...
  9. madman

    Think Low Testosterone Is Ruining Your Life? Watch This Before Starting TRT

    In this episode, Dr. Rena Malik sits down with Dr. Martin Miner, Dr. Larry Lipshultz, and Dr. Tobias S. Kohler to unpack the myths and realities of testosterone therapy. The conversation covers who truly benefits from testosterone treatment, how guidelines are evolving, distinctions between...
  10. madman

    Bipolar Androgen Therapy - Supraphysiologic Testosterone for Castrate Resistant Prostate Cancer

    * To date there's only been one randomized study testing BAT 14:05 Stop & Watch: The TRANSFORMER trial—did BAT actually work? For decades, men with prostate cancer have been told that testosterone is like gasoline on a fire. But what if, under the right conditions, testosterone could...
  11. madman

    The Testosterone Therapy Debate

    JAMA Medical News Director Jennifer Abbasi and Associate Managing Editor Kate Schweitzer discuss “Testosterone Therapy: Does New Evidence Warrant Broader Prescribing?”
  12. madman

    Are My Lab Reports Accurate: Clinical Standardization Programs Advance Quality of Laboratory Testing

    Patiently waiting! Hubert W. Vesper, Ph.D How can laboratories and researchers ensure tests used in patient care and clinical research produces accurate and comparable results...
  13. madman

    Stress-associated testosterone suppression: central adaptation or hypogonadism?

    * Severe energy deficit, sleep disruption, and uncontrollable psychogenic stress suppress hypothalamic gonadotropin-releasing hormone and luteinizing hormone pulsatility, reduce testicular androgen production, and frequently increase sex hormone–binding globulin (SHBG), thereby...
  14. madman

    Testosterone and Bone Health in Men

    * Testosterone plays an important role in the maintenance of male skeleton. Most studies of testosterone therapy have demonstrated some degree of improvement in BMD * Based on elegant mechanistic studies (discussed below), the current thinking is that both testosterone and estradiol are...
  15. madman

    Men's Health Beyond the Bedroom: PART 1

    In part one of this men’s health series, Dr. Eve Glazier and Jesse Mills, MD, health sciences clinical professor of urology and director of the Men’s Health Clinic at UCLA Health, examine how symptoms such as erectile dysfunction can offer important insights into overall health. They discuss why...
  16. madman

    Testosterone Therapy: Does New Evidence Warrant Broader Prescribing?

    * Bhasin noted that, like fellow academics and endocrinologists, he has historically been cautious around testosterone therapy. “In the last 5 years or so, we’ve learned a lot more, and I’ve changed my position,” he said. “On one side, it’s very rigid, and on the other, it’s touted as the cure...
  17. madman

    Male Fertility Uncovered: Myths, Men’s Health, and the Science Behind Declining Sperm Counts

    Who knew LOL! * Rena Malik, MD brings together leading experts Dr. Helen Bernie, Dr. James Smith, and Chief Medical Advisor of Swim Club Dr. Michael Eisenberg to discuss male infertility, declining sperm counts, and how lifestyle factors impact reproductive health. In this episode, Rena...
  18. madman

    FDA's Newest Testosterone Update | What Men Need to Know

    In this episode, Dr. Brandon and Dr. Morgentaler talk about the FDA's groundbreaking testosterone label changes, the evolving evidence on testosterone therapy and prostate cancer, and how quality of life should factor into treatment decisions for men with advanced disease. Time stamps...
  19. madman

    Balancing ADT efficacy with cardiovascular safety

    Sanoj Punnen, MD, highlights the importance of assessing and managing cardiovascular risk when initiating androgen deprivation therapy for patients with prostate cancer.
  20. madman

    Helen L. Bernie, DO, MPH, on counseling patients through TRT and prostate cancer uncertainty

    The FDA's proposed narrowing of the testosterone therapy prostate cancer contraindication to metastatic disease only reflects current clinical evidence, opening the door to testosterone therapy in appropriately selected men with treated localized prostate cancer or on active surveillance, with...
  21. madman

    FDA Testosterone Therapy Updates & the Future of Men’s Health

    In this episode of AUANews Inside Tract, host Dr. Mark Edney speaks with Dr. Helen Burnie about the FDA’s proposed updates to testosterone therapy labeling and what they could mean for urologists, patients, and the broader field of men’s health. The discussion explores new evidence on...
  22. madman

    Why Testosterone Matters for Women with Dr. Mohit Khera

    * For women, clinical discussions are currently underway with the FDA to bring regulatory approval for female-specific testosterone gels and oral formats to the US market within the next two to three years. There is an undeniable buzz around testosterone for women right now. While many...
  23. madman

    Associations of testosterone, SHBG, and related hormones with risks of cancer death, incident cancer, and incident prostate cancer

    In conclusion, men with lower testosterone concentrations had higher risk of cancer death, and men with mid-range SHBG or luteinising hormone concentrations had lower risk. Low testosterone concentrations were associated with risk of any fatal or non-fatal incident cancer. Men with lower SHBG or...
  24. madman

    TRT and non‑major adverse cardiovascular event safety signals: Atrial fibrillation acute kidney injury, and pulmonary embolism

    * This narrative review integrates randomized and real‑world evidence on TRT‑associated AF, AKI, and PE, translates these signals into practical guidance for patient selection and safety monitoring, and outlines key methodological and mechanistic priorities for future research. In contemporary...
  25. madman

    Shalin Shah - Revolutionising Testosterone Replacement Therapy

    In this episode, Shalin Shah, CEO of Marius Pharmaceuticals and a passionate advocate for testosterone education, shares insights on the misunderstood hormone that impacts both men and women. We dive into myths, testing protocols, treatment options, and the importance of early diagnosis for...
  26. madman

    New Research from Marius Pharmaceuticals Reveals Major Men's Health Awareness Gap: 65% Have Never Had Their Testosterone Levels Tested

    * The survey found that the most commonly reported symptoms over the past year (among those tested) included low energy or fatigue (48%), poor sleep (47%), reduced motivation (34%), low sex drive (28%), mood changes or irritability (27%), brain fog (26%), weight gain (26%), and reduced muscle...
  27. madman

    Testosterone and sperm may get a boost from obesity drugs

    Nature staff discuss preliminary data on the effects of GLP-1 drugs on male fertility, plus a two-year trial of a brain-computer interface. Timestamps 00:18 Brain-computer interface makes a life-changing impactNature: At-home brain implant gives man with motor neuron disease his daily life...
  28. madman

    Predicting Circulating Testosterone Concentrations in Individual Men

    * We devised a formula to calculate predicted total testosterone concentrations, based on meta-analyses of individual participant data from 21,074 men, aged 17-99 years, from nine cohort studies in Australia, Europe and North America of community-dwelling men with testosterone measured using...
  29. madman

    U.S. Department of Health and Human Services through the FDA Requested Updates to Testosterone Therapy Product Labels

    https://www.hhs.gov/press-room/fda-requests-updates-testosterone-therapy-labeling.html The U.S. Department of Health and Human Services, through the U.S. Food and Drug Administration (FDA), announced today that it is requesting updates to the prescribing information for testosterone...
  30. madman

    Is Your ED A Symptom Of Something Deadly? The Truth About Heart & Hormone Health - Roundtable

    Must listen here! Most men think erectile dysfunction is a bedroom problem and low testosterone is just a fact of getting older. This roundtable makes the case that both are early warning lights for your heart, your metabolism, and your long-term health and that ignoring them can cost...
Back
Top