Sleeping much better on Kyzatrex vs injections

[Vman]

Nice to see another Kyzatrex user

What sort of meal do you take the Kyzatrex with and how long after your dose did you get labs drawn?

My breakfast dose is with yogurt, berries and walnuts. My lunch dose is with grilled chicken and broccoli or some sort of scramble. My doc has me do labs 3-5 hours after my lunch dose.

Got my first real lab results on Kyzatrex 400mg twice daily:

5/11/2026 @ 3pm:
Total T: 2069 (250-1100 ng/dL)
Free T: 570.2 (35-155 pg/mL)
SHBG: 21 (10-50 nmol/L)
Hemoglobin: 17.6 (13.2-17.1 g/dL)
Hematocrit: 52.7 (39.4-51.1 %)
Ferritin: 31 (38-380 ng/mL)




I started taking Kyzatrex on 3/11/2026. My last blood donation was on 4/30/2026 and I did the Vorck protocol starting on that day and for 7 total days ending on 5/7/2026.


You need to stop donating to see where your hematocrit would truly sit on oral TU.

You started Kyzatrex March 11th and 50 days in donated blood on April 30th so 11 days before getting blood work done on May 11th.

Your hematocrit would have been higher than 52.7% if you never donated.

The goal here is to bring down your hematocrit and ditch the frequent blood donations which are tanking your ferritin.

My goal is exactly what you stated...to bring down hematocrit which will allow me to stop donating blood which will hopefully allow my ferritin to rise. And I want to thank you @madman! Your posts are what led me to gradually lower my daily dose from 14mg to 8mg and then to finally give Kyzatrex a try.

Unfortunately, I have had to donate blood at least every 2 months for close to 3 years now and my hematocrit is almost always at or above 54 whenever I have labs drawn. So my expectation was that my hematocrit would still be at or above 54 even with a blood donation right before labs since that's what it's always been and since there was still T cyp in my system for some of the last 2 months. I was hoping my hematocrit would be lower than 54 but I was definitely not expecting it.

So I am extremely happy that my hematocrit was only 52.7. Especially given that I had insanely high peak TT & FT on Kyzatrex! And my sleep is amazing as a completely unexpected bonus!

It's still early, but I'm hoping once my doc and I get my Kyzatrex dose dialed in I'll never need to donate blood again.